[Objective] Carrying out detailed research on the material cultural resources of national cultural parks can provide strong support for standardized park construction and resource protection and development, while also offering a new model for the value assessment of material cultural resources in similar parks. [Methods] Taking 302 material cultural resources in the East Kunlun Mountains area as the research objects and 1 km grid as the research unit, spatial analysis and value evaluation methods were adopted to explore their spatial differentiation pattern, comprehensively assess the value of material cultural resources in this region, and provide a practical path for the construction of the East Kunlun Mountain Cultural Park. [Results] (1) The material cultural resources in the East Kunlun Mountain Cultural Park generally present a hierarchical pattern of “single-core agglomeration-peripheral dispersion”. The hotspots are concentrated in low-altitude areas such as Dulan County and Xinghai County in the northern foot, and the sub-hotspots form dual characteristics of “radiation dependence” and “endogenous drive”; the agglomeration of resources is prominent, which can be summarized as a “one-core and multi-belt” model, forming one high-density core area in “Xinghai County-Tongde County” and one small sub-core in northern Dulan County. (2) The average value of resource development conditions in the study area is 8.29×10^-4, which is at a relatively high level overall; however, the overall levels of indicators such as resource value (average value 0.31×10^-4), resource attributes (average value 0.67×10^-4), natural environment conditions (average value 12.47×10^-4), and social and economic conditions (average value 20.43×10^-4) are all in the median area. (3) There are significant differences in the comprehensive value of material cultural resources between the northern and southern foots of the study area, showing a spatial differentiation pattern where the northern foot is relatively higher than the alpine area in the southern foot, and the overall value is at the median level. [Conclusion] The overall resource development conditions in the study area are good, but the intrinsic value of the resource itself (resource value, resource attributes) and the external supporting conditions (natural environment conditions, social and economic conditions) are both at a medium level, with significant spatial differentiation. Based on this result, it is suggested to construct a heritage corridor system of “one core, two wings and five nodes”, establish multi-functional cultural areas, implement a multi-element combined development strategy, and take multi-dimensional measures to promote the protection of material cultural resources and the construction of cultural parks.