Article(id=1276975957688840303, tenantId=1146029695717560320, journalId=1276577828834349082, issueId=1276975955985961244, articleNumber=null, orderNo=null, doi=10.19540/j.cnki.cjcmm.20250917.501, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1752681600000, receivedDateStr=2025-07-17, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1782384393379, onlineDateStr=2026-06-25, pubDate=1767196800000, pubDateStr=2026-01-01, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1782384393379, onlineIssueDateStr=2026-06-25, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1782384393379, creator=13701087609, updateTime=1782384393379, updator=13701087609, issue=Issue{id=1276975955985961244, tenantId=1146029695717560320, journalId=1276577828834349082, year='2026', volume='51', issue='1', pageStart='1', pageEnd='300', issueExtLink='null', onlineDate='null', pubDate='1767196800000', pubDateStr='2026-01-01', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1782384392973, creator='13701087609', updateTime=1782384484405, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1276976339546673871, tenantId=1146029695717560320, journalId=1276577828834349082, issueId=1276975955985961244, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1276976339546673872, tenantId=1146029695717560320, journalId=1276577828834349082, issueId=1276975955985961244, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=281, endPage=300, ext={EN=ArticleExt(id=1276975958414454897, articleId=1276975957688840303, tenantId=1146029695717560320, journalId=1276577828834349082, language=EN, title=Network Meta-analysis of traditional Chinese medicine injections combined with conventional western medicine for treatment of chronic obstructive pulmonary disease with respiratory failure, columnId=null, journalTitle=Chinese Journal of Traditional Chinese Medicine, columnName=null, runingTitle=null, highlight=null, articleAbstract=

This study aims to compare the efficacy and safety of different traditional Chinese medicine injections (TCMIs) combined with conventional western medicine in the treatment of chronic obstructive pulmonary disease (COPD) with respiratory failure (RF) using a network Meta-analysis approach. A comprehensive literature search was conducted in CNKI, VIP, Wanfang, SinoMed, Web of Science, PubMed, Cochrane Library, and EMbase databases from inception to June 29, 2025. Randomized controlled trials (RCTs) were performed by employing the literature on the treatment of COPD with RF by TCMIs, and data were analyzed by Stata 17. A total of 110 RCTs involving 9 218 participants and 11 different TCMIs were included. The ranking of efficacy in the surface under the cumulative ranking curve (SUCRA) from network Meta-analysis was as follows: ① for improving clinical total response rate, Chuanxiongqin Injection + conventional western medicine, Shankezhi Injection + conventional western medicine, and Danhong Injection + conventional western medicine ranked top three; ② for reducing mortality, Chuanxiongqin Injection + conventional western medicine, Danshen Chuanxiongqin Injection + conventional western medicine, and Shenfu Injection + conventional western medicine ranked top three; ③ for shortening length of hospital stay, Danshen Chuanxiongqin Injection + conventional western medicine, Shenfu Injection + conventional western medicine, and Shenmai Injection + conventional western medicine ranked top three; ④ for reducing duration of mechanical ventilation, Shenqi Fuzheng Injection + conventional western medicine, Shenmai Injection + conventional western medicine, and Tanreqing Injection + conventional western medicine ranked top three; ⑤ for improving arterial partial pressure of oxygen (PaO₂), Chuanxiongqin Injection + conventional western medicine, Danshen Injection + conventional western medicine, and Danhong Injection + conventional western medicine ranked top three; ⑥ for reducing arterial partial pressure of carbon dioxide (PaCO₂), Shenfu Injection + conventional western medicine, Tanreqing Injection + conventional western medicine, and Danshen Chuanxiongqin Injection + conventional western medicine ranked top three; ⑦ for improving arterial oxygen saturation (SaO₂), Shenqi Fuzheng Injection + conventional western medicine, Xuebijing Injection + conventional western medicine, and Xingnaojing Injection +conventional western medicine ranked top three; ⑧ for improving forced expiratory volume in one second (FEV₁), Chuanxiongqin Injection + conventional western medicine, Shenmai Injection + conventional western medicine, and Tanreqing Injection + conventional western medicine ranked top three; ⑨ for improving forced vital capacity (FVC), Danshen Chuanxiongqin Injection + conventional western medicine, Xuebijing Injection + conventional western medicine, and Tanreqing Injection + conventional western medicine ranked top three. In terms of safety, adverse events were mostly mild and occurred at a low incidence. In conclusion, TCMIs combined with conventional western medicine may offer clinical benefits in the management of COPD with RF. However, due to limitations in the number and quality of studies for each intervention, further rigorously designed RCT should be conducted to validate these findings.

, authors=null, authorsList=Wen-shuai JI, Kang ZHANG, Hao YANG, Wen-jing YIN, Xin-yu MIAO, Xiao-xuan HE, Peng-zhen JING, Hai-feng WANG, authorCompany=null, correspAuthors=Hai-feng WANG, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1276975959341396084, articleId=1276975957688840303, tenantId=1146029695717560320, journalId=1276577828834349082, language=CN, title=不同中药注射液联合常规西医治疗慢性阻塞性肺疾病合并呼吸衰竭的网状Meta分析, columnId=1276975958527701106, journalTitle=中国中药杂志, columnName=临床, runingTitle=null, highlight=null, articleAbstract=

采用网状Meta分析比较不同中药注射液联合常规西医治疗慢性阻塞性肺疾病合并呼吸衰竭的有效性和安全性。计算机检索中国知网（CNKI）、维普（VIP）、万方（Wanfang）、中国生物医学文献服务系统（SinoMed）、Web of Science、PubMed、Cochrane Library、EMbase数据库，检索建库至2025年6月29日收录的有关中药注射液治疗慢性阻塞性肺疾病合并呼吸衰竭的随机对照试验（RCT），采用Stata 17软件进行数据分析。最终纳入110篇RCTs，总样本量9 218例，涉及11种中药注射液。网状Meta分析显示，①提高临床总有效率方面，累计概率排名曲线下面积（SUCRA）排名前3的依次为川芎嗪注射液+常规西医、喘可治注射液+常规西医、丹红注射液+常规西医；②降低病死率方面，SUCRA排名前3的依次为川芎嗪注射液+常规西医、丹参川芎嗪注射液+常规西医、参附注射液+常规西医；③减少住院时间方面，SUCRA排名前3的依次为丹参川芎嗪注射液+常规西医、参附注射液+常规西医、参麦注射液+常规西医；④减少机械通气时间方面，SUCRA排名前3的依次为参芪扶正注射液+常规西医、参麦注射液+常规西医、痰热清注射液+常规西医；⑤改善动脉血氧分压（PaO₂）方面，SUCRA排名前3的依次为川芎嗪注射液+常规西医、丹参注射液+常规西医、丹红注射液+常规西医；⑥改善动脉血二氧化碳分压（PaCO₂）方面，SUCRA排名前3的依次为参附注射液+常规西医、痰热清注射液+常规西医、丹参川芎嗪注射液+常规西医；⑦改善动脉血氧饱和度（SaO₂）方面，SUCRA排名前3的依次为参芪扶正注射液+常规西医、血必净注射液+常规西医、醒脑静注射液+常规西医；⑧改善1 s用力呼气容积（FEV₁）方面，SUCRA排名前3的依次为川芎嗪注射液+常规西医、参麦注射液+常规西医、痰热清注射液+常规西医；⑨改善用力呼气量（FVC）方面，SUCRA排名前3的依次为丹参川芎嗪注射液+常规西医、血必净注射液+常规西医、痰热清注射液+常规西医。安全性方面，不良反应多为轻度且发生率较低。结果表明，中药注射液联合常规西医能够提高慢性阻塞性肺疾病合并呼吸衰竭的临床疗效，但由于不同干预措施纳入研究数量和质量的局限性，该结论仍需开展更多设计严谨的RCT予以验证。

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姬文帅，博士研究生，E-mail: jiw_shuai@163.com

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