Article(id=1276975972624761619, tenantId=1146029695717560320, journalId=1276577828834349082, issueId=1276975955985961244, articleNumber=null, orderNo=null, doi=10.19540/j.cnki.cjcmm.20251011.703, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1756137600000, receivedDateStr=2025-08-26, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1782384396939, onlineDateStr=2026-06-25, pubDate=1767196800000, pubDateStr=2026-01-01, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1782384396939, onlineIssueDateStr=2026-06-25, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1782384396939, creator=13701087609, updateTime=1782384396939, updator=13701087609, issue=Issue{id=1276975955985961244, tenantId=1146029695717560320, journalId=1276577828834349082, year='2026', volume='51', issue='1', pageStart='1', pageEnd='300', issueExtLink='null', onlineDate='null', pubDate='1767196800000', pubDateStr='2026-01-01', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1782384392973, creator='13701087609', updateTime=1782384484405, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1276976339546673871, tenantId=1146029695717560320, journalId=1276577828834349082, issueId=1276975955985961244, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1276976339546673872, tenantId=1146029695717560320, journalId=1276577828834349082, issueId=1276975955985961244, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=40, endPage=49, ext={EN=ArticleExt(id=1276975973044192021, articleId=1276975972624761619, tenantId=1146029695717560320, journalId=1276577828834349082, language=EN, title=Research progress in neuroprotective effects of Bacopa monnieri active components and derivatives in neurological disorders, columnId=null, journalTitle=Chinese Journal of Traditional Chinese Medicine, columnName=null, runingTitle=null, highlight=null, articleAbstract=

Bacopa monnieri, a plant of Scrophulariaceae, has a long history of medicinal use and is recognized as a traditional medicinal herb in multiple countries. Neurological disorders, due to their extensive damage to neural functions, have become a major public health challenge and garnered worldwide attention. In ancient times, B. monnieri was documented for treating cognitive and memory impairments. Recent studies have elucidated its pharmacological mechanisms and therapeutic targets underpinning the neuroprotective effect. However, the molecular mechanisms of its active ingredients have not been systematically summarized. This study is the first to integrate the target sites of its core ingredients across multiple categories of neurological disorders. It summarizes the pharmacological mechanisms of B. monnieri as well as its active ingredients and derivatives in various neurological diseases, which exert neuroprotective effects through multi-target interactions. This paper provides novel strategies for developing botanical drugs targeting diseases like Alzheimer's and epilepsy and aims to offer evidence-based guidance for the development and application of B. monnieri in functional foods, health supplements, and pharmaceuticals.

, authors=null, authorsList=Lyu-yuan LIANG, Jia-lei CAO, Zi-lin ZHAO, Yi-fan QI, Yan-hua WANG, Shang-ming FANG, Shuai-bin DONG, Yun-kai WANG, Xiang-han TAN, Bing-qi WEI, Bing-xiang MA, Jie-qiong CUI, authorCompany=null, correspAuthors=Bing-xiang MA, Jie-qiong CUI, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1276975973467816727, articleId=1276975972624761619, tenantId=1146029695717560320, journalId=1276577828834349082, language=CN, title=假马齿苋活性成分及其衍生物对神经系统疾病的保护作用研究进展, columnId=1276975957151977760, journalTitle=中国中药杂志, columnName=综述, runingTitle=null, highlight=null, articleAbstract=

假马齿苋Bacopa monnieri为玄参科假马齿苋属植物，用药历史悠久，是多个国家的传统药用植物。神经系统疾病因其造成广泛神经功能损害，已构成重大公共卫生挑战，得到世界关注。古代假马齿苋被记载用于治疗认知记忆损伤，近年多项研究揭示假马齿苋神经保护作用的药理机制和功效靶点，但其活性成分的分子机制尚未系统总结。该文首次整合其核心成分在多种神经系统疾病中的作用靶点，总结了假马齿苋及其活性成分和衍生物在多种神经系统疾病的药理机制，通过多靶点互作发挥神经保护作用，为开发针对阿尔茨海默病、癫痫等疾病的植物药提供新策略，以期为假马齿苋的食品、保健食品及药品开发应用提供科学参考。

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