Article(id=1276975957084865219, tenantId=1146029695717560320, journalId=1276577828834349082, issueId=1276975955985961244, articleNumber=null, orderNo=null, doi=10.19540/j.cnki.cjcmm.20251009.201, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1749139200000, receivedDateStr=2025-06-06, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1782384393235, onlineDateStr=2026-06-25, pubDate=1767196800000, pubDateStr=2026-01-01, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1782384393235, onlineIssueDateStr=2026-06-25, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1782384393235, creator=13701087609, updateTime=1782384393235, updator=13701087609, issue=Issue{id=1276975955985961244, tenantId=1146029695717560320, journalId=1276577828834349082, year='2026', volume='51', issue='1', pageStart='1', pageEnd='300', issueExtLink='null', onlineDate='null', pubDate='1767196800000', pubDateStr='2026-01-01', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1782384392973, creator='13701087609', updateTime=1782384484405, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1276976339546673871, tenantId=1146029695717560320, journalId=1276577828834349082, issueId=1276975955985961244, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1276976339546673872, tenantId=1146029695717560320, journalId=1276577828834349082, issueId=1276975955985961244, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=19, endPage=31, ext={EN=ArticleExt(id=1276975957474935493, articleId=1276975957084865219, tenantId=1146029695717560320, journalId=1276577828834349082, language=EN, title=Mechanisms of miRNA in osteoarthritis and research advances in traditional Chinese medicine intervention, columnId=null, journalTitle=Chinese Journal of Traditional Chinese Medicine, columnName=null, runingTitle=null, highlight=null, articleAbstract=

Osteoarthritis (OA) is a common degenerative joint disease characterized by cartilage degeneration, synovial inflammation, osteophyte formation, and joint space narrowing, seriously impairing patients' mobility and quality of life. The pathogenesis of OA is highly complex, involving multiple cell types and signaling pathways. Key pathological processes include abnormal chondrocyte function, sustained activation of inflammatory responses, and imbalances in apoptosis and autophagy. In recent years, microRNAs (miRNAs), small non-coding RNAs, have been recognized for their crucial roles in regulating gene expression and influencing the progression of various diseases. miRNAs exhibit important regulatory functions in OA-related processes such as inflammatory regulation, chondrocyte apoptosis and autophagy, extracellular matrix metabolism, and subchondral bone remodeling. Multiple specific miRNAs have been shown to be closely associated with the onset and progression of OA, demonstrating potential diagnostic and therapeutic value. Traditional Chinese medicine (TCM) is an important treatment approach for OA, offering advantages such as multi-component, multi-target, and multi-pathway regulation. Recent studies have shown that TCM single herbs, compound prescriptions, acupuncture, and moxibustion can upregulate or downregulate the expression of specific miRNAs, thereby intervening in their downstream target genes and related signaling pathways. This leads to anti-inflammatory and analgesic effects, inhibition of chondrocyte apoptosis, promotion of matrix synthesis, and cartilage repair. This review systematically summarizes the mechanisms of miRNAs in the progression of OA, with a focus on the latest research advances in TCM regulation of miRNAs to intervene in OA. The aim is to provide a theoretical basis and new insights for the early molecular diagnosis, targeted therapy, and modern research and clinical translation of TCM in OA.

, authors=null, authorsList=Hai-dong ZHOU, Hui LUO, Liang-shen HU, Feng-ting ZHANG, Wen-tao HU, Jie-fei XIE, Yao-hong LU, Ji-chun SHAN, Shao-yong FAN, Yu-wen CHEN, authorCompany=null, correspAuthors=Yu-wen CHEN, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1276975957999223495, articleId=1276975957084865219, tenantId=1146029695717560320, journalId=1276577828834349082, language=CN, title=miRNA在骨性关节炎中的作用机制及中医药干预研究进展, columnId=1276975957151977760, journalTitle=中国中药杂志, columnName=综述, runingTitle=null, highlight=null, articleAbstract=

骨性关节炎（osteoarthritis, OA）是一种常见的退行性骨关节疾病，其主要特征包括关节软骨退变、滑膜炎症、骨赘形成及关节间隙狭窄等，严重影响患者的活动能力和生活质量。OA的发病机制十分复杂，涉及多种细胞类型和信号通路，其中软骨细胞的异常功能、炎症反应的持续激活及细胞凋亡和自噬失衡等是其关键病理过程。近年来，微小核糖核酸（miRNA）作为一种小分子非编码RNA，通过调控基因表达，在多种疾病的发生发展中发挥重要作用。miRNA在OA的炎症调控、软骨细胞凋亡与自噬、细胞外基质代谢、软骨下骨重塑等方面均具有重要调控功能，多个特定miRNA被证实与OA的发生发展密切相关，具有潜在的诊断和治疗价值。中医药作为传统治疗OA的重要手段，具有多成分、多靶点、多通路的调控优势，近年来研究发现，中药单体、中药复方及针灸疗法可通过上调或下调特定miRNA的表达，干预其下游靶基因和相关信号通路，从而发挥抗炎镇痛、抑制软骨细胞凋亡、促进基质合成及软骨修复等作用。该文系统综述了miRNA在OA发生发展过程中的作用机制，重点探讨了中医药通过调控miRNA干预OA的最新研究进展，旨在为OA的早期分子诊断、靶向治疗以及中医药的现代化研究与临床转化应用提供理论依据和新思路。

, authors=, authorsList=周海东, 罗晖, 胡梁深, 张凤婷, 胡文涛, 谢杰飞, 卢姚宏, 单记春, 范少勇, 陈虞文, authorCompany=null, correspAuthors=陈虞文, authorNote=null, correspAuthorsNote=, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=QeCXnVaHXpT9zjA+0j/xUQ==, magXml=8uZTYwH+rh5c25NpExOISg==, pdfUrl=null, pdf=f6aEBDX8u9RWw6EAAMJGYQ==, pdfFileSize=384900, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=JOMiGLxzF9/F4NcbtDAw8g==, mapNumber=null, fund=null)}, authors=[Author(id=1276975959110714069, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=291074907@qq.com, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1276975959194600152, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, authorId=1276975959110714069, language=EN, stringName=Hai-dong ZHOU, firstName=Hai-dong, middleName=null, lastName=ZHOU, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1.Clinical Medical College, Jiangxi University of Chinese Medicine, Nanchang 330004, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1276975959542727385, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, authorId=1276975959110714069, language=CN, stringName=周海东, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1．江西中医药大学 临床医学院，江西 南昌 330004, bio={"content":"

周海东，博士研究生，E-mail: 291074907@qq.com

"}, bioImg=null, bioContent=

周海东，博士研究生，E-mail: 291074907@qq.com

, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1276975958326379209, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, xref=1., ext=[AuthorCompanyExt(id=1276975958334767818, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, companyId=1276975958326379209, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^1.Clinical Medical College, Jiangxi University of Chinese Medicine, Nanchang 330004, China), AuthorCompanyExt(id=1276975958343156427, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, companyId=1276975958326379209, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^1．江西中医药大学 临床医学院，江西 南昌 330004)])]), Author(id=1276975959609836251, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, orderNo=1, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1276975959953769181, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, authorId=1276975959609836251, language=EN, stringName=Hui LUO, firstName=Hui, middleName=null, lastName=LUO, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1.Clinical Medical College, Jiangxi University of Chinese Medicine, Nanchang 330004, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1276975960025072350, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, authorId=1276975959609836251, language=CN, stringName=罗晖, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1．江西中医药大学 临床医学院，江西 南昌 330004, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1276975958326379209, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, xref=1., ext=[AuthorCompanyExt(id=1276975958334767818, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, companyId=1276975958326379209, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^1.Clinical Medical College, Jiangxi University of Chinese Medicine, Nanchang 330004, China), AuthorCompanyExt(id=1276975958343156427, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, companyId=1276975958326379209, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^1．江西中医药大学 临床医学院，江西 南昌 330004)])]), Author(id=1276975960381588192, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, orderNo=2, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1276975960457085666, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, authorId=1276975960381588192, language=EN, stringName=Liang-shen HU, firstName=Liang-shen, middleName=null, lastName=HU, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=², address=^2.Hongdu Hospital of Chinese Medicine Affiliated to Jiangxi University of Chinese Medicine, Nanchang 330038, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1276975960805212899, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, authorId=1276975960381588192, language=CN, stringName=胡梁深, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=², address=^2．江西中医药大学附属洪都中医院，江西 南昌 330038, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1276975958418653900, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, xref=2., ext=[AuthorCompanyExt(id=1276975958427042509, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, companyId=1276975958418653900, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^2.Hongdu Hospital of Chinese Medicine Affiliated to Jiangxi University of Chinese Medicine, Nanchang 330038, China), AuthorCompanyExt(id=1276975958439625422, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, companyId=1276975958418653900, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^2．江西中医药大学附属洪都中医院，江西 南昌 330038)])]), Author(id=1276975960897487589, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, orderNo=3, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1276975961220448999, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, authorId=1276975960897487589, language=EN, stringName=Feng-ting ZHANG, firstName=Feng-ting, middleName=null, lastName=ZHANG, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=³, address=^3.Affiliated Hospital of Jiangxi University of Chinese Medicine, Nanchang 330006, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1276975961291752168, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, authorId=1276975960897487589, language=CN, stringName=张凤婷, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=³, address=^3．江西中医药大学附属医院，江西 南昌 330006, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1276975958817112784, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, xref=3., ext=[AuthorCompanyExt(id=1276975958825501393, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, companyId=1276975958817112784, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^3.Affiliated Hospital of Jiangxi University of Chinese Medicine, Nanchang 330006, China), AuthorCompanyExt(id=1276975958838084306, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, companyId=1276975958817112784, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^3．江西中医药大学附属医院，江西 南昌 330006)])]), Author(id=1276975961652462314, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, orderNo=4, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1276975961719571180, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, authorId=1276975961652462314, language=EN, stringName=Wen-tao HU, firstName=Wen-tao, middleName=null, lastName=HU, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1.Clinical Medical College, Jiangxi University of Chinese Medicine, Nanchang 330004, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1276975962042532589, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, authorId=1276975961652462314, language=CN, stringName=胡文涛, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1．江西中医药大学 临床医学院，江西 南昌 330004, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1276975958326379209, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, xref=1., ext=[AuthorCompanyExt(id=1276975958334767818, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, companyId=1276975958326379209, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^1.Clinical Medical College, Jiangxi University of Chinese Medicine, Nanchang 330004, China), AuthorCompanyExt(id=1276975958343156427, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, companyId=1276975958326379209, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^1．江西中医药大学 临床医学院，江西 南昌 330004)])]), Author(id=1276975962109641455, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, orderNo=5, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1276975962466157297, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, authorId=1276975962109641455, language=EN, stringName=Jie-fei XIE, firstName=Jie-fei, middleName=null, lastName=XIE, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1.Clinical Medical College, Jiangxi University of Chinese Medicine, Nanchang 330004, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1276975962529071858, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, authorId=1276975962109641455, language=CN, stringName=谢杰飞, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1．江西中医药大学 临床医学院，江西 南昌 330004, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1276975958326379209, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, xref=1., ext=[AuthorCompanyExt(id=1276975958334767818, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, companyId=1276975958326379209, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^1.Clinical Medical College, Jiangxi University of Chinese Medicine, Nanchang 330004, China), AuthorCompanyExt(id=1276975958343156427, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, companyId=1276975958326379209, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^1．江西中医药大学 临床医学院，江西 南昌 330004)])]), Author(id=1276975962864616180, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, orderNo=6, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1276975962940113654, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, authorId=1276975962864616180, language=EN, stringName=Yao-hong LU, firstName=Yao-hong, middleName=null, lastName=LU, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1.Clinical Medical College, Jiangxi University of Chinese Medicine, Nanchang 330004, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1276975962998833911, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, authorId=1276975962864616180, language=CN, stringName=卢姚宏, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1．江西中医药大学 临床医学院，江西 南昌 330004, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1276975958326379209, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, xref=1., ext=[AuthorCompanyExt(id=1276975958334767818, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, companyId=1276975958326379209, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^1.Clinical Medical College, Jiangxi University of Chinese Medicine, Nanchang 330004, China), AuthorCompanyExt(id=1276975958343156427, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, companyId=1276975958326379209, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^1．江西中医药大学 临床医学院，江西 南昌 330004)])]), Author(id=1276975963061748473, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, orderNo=7, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1276975963414070011, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, authorId=1276975963061748473, language=EN, stringName=Ji-chun SHAN, firstName=Ji-chun, middleName=null, lastName=SHAN, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=², address=^2.Hongdu Hospital of Chinese Medicine Affiliated to Jiangxi University of Chinese Medicine, Nanchang 330038, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1276975963724448508, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, authorId=1276975963061748473, language=CN, stringName=单记春, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=², address=^2．江西中医药大学附属洪都中医院，江西 南昌 330038, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1276975958418653900, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, xref=2., ext=[AuthorCompanyExt(id=1276975958427042509, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, companyId=1276975958418653900, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^2.Hongdu Hospital of Chinese Medicine Affiliated to Jiangxi University of Chinese Medicine, Nanchang 330038, China), AuthorCompanyExt(id=1276975958439625422, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, companyId=1276975958418653900, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^2．江西中医药大学附属洪都中医院，江西 南昌 330038)])]), Author(id=1276975963816723198, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, orderNo=8, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1276975964194210560, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, authorId=1276975963816723198, language=EN, stringName=Shao-yong FAN, firstName=Shao-yong, middleName=null, lastName=FAN, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=², address=^2.Hongdu Hospital of Chinese Medicine Affiliated to Jiangxi University of Chinese Medicine, Nanchang 330038, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1276975964592669441, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, authorId=1276975963816723198, language=CN, stringName=范少勇, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=², address=^2．江西中医药大学附属洪都中医院，江西 南昌 330038, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1276975958418653900, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, xref=2., ext=[AuthorCompanyExt(id=1276975958427042509, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, companyId=1276975958418653900, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^2.Hongdu Hospital of Chinese Medicine Affiliated to Jiangxi University of Chinese Medicine, Nanchang 330038, China), AuthorCompanyExt(id=1276975958439625422, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, companyId=1276975958418653900, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^2．江西中医药大学附属洪都中医院，江西 南昌 330038)])]), Author(id=1276975964659778307, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, orderNo=9, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=594049402@qq.com, emailSecond=null, emailThird=null, correspondingAuthor=1, authorType=1, ext={EN=AuthorExt(id=1276975965079208709, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, authorId=1276975964659778307, language=EN, stringName=Yu-wen CHEN, firstName=Yu-wen, middleName=null, lastName=CHEN, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=^{3, *}, address=^3.Affiliated Hospital of Jiangxi University of Chinese Medicine, Nanchang 330006, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1276975965418947334, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, authorId=1276975964659778307, language=CN, stringName=陈虞文, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=^{3, *}, address=^3．江西中医药大学附属医院，江西 南昌 330006, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1276975958817112784, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, xref=3., ext=[AuthorCompanyExt(id=1276975958825501393, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, companyId=1276975958817112784, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^3.Affiliated Hospital of Jiangxi University of Chinese Medicine, Nanchang 330006, China), AuthorCompanyExt(id=1276975958838084306, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, companyId=1276975958817112784, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^3．江西中医药大学附属医院，江西 南昌 330006)])])], keywords=[Keyword(id=1276975966241030919, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, language=EN, orderNo=1, keyword=osteoarthritis), Keyword(id=1276975966677238536, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, language=EN, orderNo=2, keyword=miRNA), Keyword(id=1276975967105057545, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, language=EN, orderNo=3, keyword=traditional Chinese medicine), Keyword(id=1276975967511905034, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, language=EN, orderNo=4, keyword=research progress), Keyword(id=1276975967914558219, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, language=CN, orderNo=1, keyword=骨性关节炎), Keyword(id=1276975968329794316, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, language=CN, orderNo=2, keyword=miRNA), Keyword(id=1276975968430457613, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, language=CN, orderNo=3, keyword=中医药), Keyword(id=1276975969181238030, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, language=CN, orderNo=4, keyword=研究进展)], refs=null, funds=[Fund(id=1276975969592279823, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, awardId=20202BBG73028, language=CN, fundingSource=江西省重点研发计划项目(20202BBG73028), fundOrder=null, country=null), Fund(id=1276975969676165904, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, awardId=202410412281, language=CN, fundingSource=2024年江西省校级大学生创新创业训练计划项目(202410412281), fundOrder=null, country=null), Fund(id=1276975970024293137, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, awardId=YC2024-B239, language=CN, fundingSource=2024年江西省研究生创新专项资金项目(YC2024-B239), fundOrder=null, country=null), Fund(id=1276975970108179218, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, awardId=GJJ2200986, language=CN, fundingSource=江西省教育厅科学技术研究项目(GJJ2200986), fundOrder=null, country=null)], companyList=[AuthorCompany(id=1276975958326379209, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, xref=1., ext=[AuthorCompanyExt(id=1276975958334767818, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, companyId=1276975958326379209, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^1.Clinical Medical College, Jiangxi University of Chinese Medicine, Nanchang 330004, China), AuthorCompanyExt(id=1276975958343156427, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, companyId=1276975958326379209, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^1．江西中医药大学 临床医学院，江西 南昌 330004)]), AuthorCompany(id=1276975958418653900, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, xref=2., ext=[AuthorCompanyExt(id=1276975958427042509, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, companyId=1276975958418653900, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^2.Hongdu Hospital of Chinese Medicine Affiliated to Jiangxi University of Chinese Medicine, Nanchang 330038, China), AuthorCompanyExt(id=1276975958439625422, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, companyId=1276975958418653900, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^2．江西中医药大学附属洪都中医院，江西 南昌 330038)]), AuthorCompany(id=1276975958817112784, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, xref=3., ext=[AuthorCompanyExt(id=1276975958825501393, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, companyId=1276975958817112784, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^3.Affiliated Hospital of Jiangxi University of Chinese Medicine, Nanchang 330006, China), AuthorCompanyExt(id=1276975958838084306, tenantId=1146029695717560320, journalId=1276577828834349082, articleId=1276975957084865219, companyId=1276975958817112784, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^3．江西中医药大学附属医院，江西 南昌 330006)])], figs=null, attaches=null, journal=Journal(id=1276576774675730453, delFlag=0, nameCn=中国中药杂志, nameEn=Chinese Journal of Traditional Chinese Medicine, nameHistory1=null, nameHistory2=null, issn=1001-5302, eissn=2097-5066, cn=11-2272/R, coden=null, periodic=3, language=CN, oaType=null, ccby=null, superviseOffice=null, ownerOffice=null, pubOffice=null, editorOffice=null, officeType=null, aims=null, clcCode=null, officeProv=null, officeCity=null, officeAddr=null, officeZip=null, officeEmail=null, officePhone=null, editDirector=null, officeDirector=null, officeDirectorPhone=null, officeStaffNum=null, officeEmpNum=null, coverPicUrl=Wp+xVi2pFpMjZtgAvUPqBA==, journalPrice=null, startedYear=null, abbrevIsoEn=Chinese Journal of Traditional Chinese Medicine, journalRemark=null, publicationField=null, createdTime=1782289220734, updatedTime=1784021766041, createdBy=18614031015, updatedBy=13041195026, firstLetterCn=Z, firstLetterEn=Z, subjectCode=Life Sciences, subjectName=null, subjectCodeEn=Life Sciences, subjectNameEn=null, picCn=Wp+xVi2pFpMjZtgAvUPqBA==, picEn=+6LpkbuqcMxcXTbcXC5SRA==, jcr=null, cjcr=null, exts=[JournalExt(id=1283843596482744979, language=CN, name=中国中药杂志, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1784021766062, updatedTime=1784021766062, createdBy=13041195026, updatedBy=13041195026, submissionGuidelinesUrl=, submissionAuthorUrl=https://cacm.tcmjc.com/CJCMM, submissionEditorUrl=https://cacm.tcmjc.com/CJCMM, submissionReviewUrl=https://cacm.tcmjc.com/CJCMM, submissionCeEditorUrl=, submissionAeEditorUrl=, option={"copyright":""}), JournalExt(id=1283843596537270932, language=EN, name=Chinese Journal of Traditional Chinese Medicine, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1784021766075, updatedTime=1784021766075, createdBy=13041195026, updatedBy=13041195026, submissionGuidelinesUrl=, submissionAuthorUrl=https://cacm.tcmjc.com/CJCMM, submissionEditorUrl=https://cacm.tcmjc.com/CJCMM, submissionReviewUrl=https://cacm.tcmjc.com/CJCMM, submissionCeEditorUrl=, submissionAeEditorUrl=, option={"copyright":""})], databaseList=null, tenantJournalId=1276577828834349082, websiteList=[Website(id=1276578024996864213, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1276577828834349082, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/zgzyzz/CN, language=CN, createTime=1782289518832, createBy=18614031015, updateTime=1782290501435, updateBy=18614031015, name=中国中药杂志-中文, tplId=1146099689490845704, title=中国中药杂志, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1276582276515369131, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1276578024996864213, code=articleTextType, value=kx, createTime=1782290532473, updateTime=1782290532473, creator=18614031015, updator=18614031015), WebsiteProps(id=1276582276490203304, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1276578024996864213, code=banner, value=null, createTime=1782290532467, updateTime=1782290532467, creator=18614031015, updator=18614031015), WebsiteProps(id=1276582276536340654, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1276578024996864213, code=grayFlag, value=0, createTime=1782290532478, updateTime=1782290532478, creator=18614031015, updator=18614031015), WebsiteProps(id=1276582276477620391, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1276578024996864213, code=logo, value=https://castjournals.cast.org.cn/joweb/zgzyzz/CN/file/pic?fileId=tqs6u8GE413e8rN+h8xxag==, createTime=1782290532464, updateTime=1782290532464, creator=18614031015, updator=18614031015), WebsiteProps(id=1276582276548923568, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1276578024996864213, code=minRunFlag, value=0, createTime=1782290532481, updateTime=1782290532481, creator=18614031015, updator=18614031015), WebsiteProps(id=1276582276506980522, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1276578024996864213, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/zgzyzz/CN/file/pic, createTime=1782290532471, updateTime=1782290532471, creator=18614031015, updator=18614031015), WebsiteProps(id=1276582276540534959, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1276578024996864213, code=silenceFlag, value=0, createTime=1782290532479, updateTime=1782290532479, creator=18614031015, updator=18614031015), WebsiteProps(id=1276582276498591913, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1276578024996864213, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_cn_619/, createTime=1782290532469, updateTime=1782290532469, creator=18614031015, updator=18614031015), WebsiteProps(id=1276582276523757740, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1276578024996864213, code=themeColor, value=null, createTime=1782290532475, updateTime=1782290532475, creator=18614031015, updator=18614031015), WebsiteProps(id=1276582276527952045, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1276578024996864213, code=themeStyle, value=null, createTime=1782290532476, updateTime=1782290532476, creator=18614031015, updator=18614031015)]), Website(id=1276578025101721818, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1276577828834349082, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/zgzyzz/EN, language=EN, createTime=1782289518857, createBy=18614031015, updateTime=1782290498024, updateBy=18614031015, name=中国中药杂志-英文, tplId=1146101810881728533, title=Chinese Journal of Traditional Chinese Medicine, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1276582244294725793, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1276578025101721818, code=articleTextType, value=kx, createTime=1782290524791, updateTime=1782290524791, creator=18614031015, updator=18614031015), WebsiteProps(id=1276582244269559966, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1276578025101721818, code=banner, value=null, createTime=1782290524785, updateTime=1782290524785, creator=18614031015, updator=18614031015), WebsiteProps(id=1276582244328280228, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1276578025101721818, code=grayFlag, value=0, createTime=1782290524799, updateTime=1782290524799, creator=18614031015, updator=18614031015), WebsiteProps(id=1276582244256977053, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1276578025101721818, code=logo, value=https://castjournals.cast.org.cn/joweb/zgzyzz/EN/file/pic?fileId=tqs6u8GE413e8rN+h8xxag==, createTime=1782290524782, updateTime=1782290524782, creator=18614031015, updator=18614031015), WebsiteProps(id=1276582244345057446, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1276578025101721818, code=minRunFlag, value=0, createTime=1782290524803, updateTime=1782290524803, creator=18614031015, updator=18614031015), WebsiteProps(id=1276582244286337184, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1276578025101721818, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/zgzyzz/EN/file/pic, createTime=1782290524789, updateTime=1782290524789, creator=18614031015, updator=18614031015), WebsiteProps(id=1276582244336668837, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1276578025101721818, code=silenceFlag, value=0, createTime=1782290524801, updateTime=1782290524801, creator=18614031015, updator=18614031015), WebsiteProps(id=1276582244277948575, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1276578025101721818, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_en_623/, createTime=1782290524787, updateTime=1782290524787, creator=18614031015, updator=18614031015), WebsiteProps(id=1276582244303114402, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1276578025101721818, code=themeColor, value=null, createTime=1782290524793, updateTime=1782290524793, creator=18614031015, updator=18614031015), WebsiteProps(id=1276582244315697315, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1276578025101721818, code=themeStyle, value=null, createTime=1782290524796, updateTime=1782290524796, creator=18614031015, updator=18614031015)])], journalTitle=中国中药杂志, weixinUrl=null, journalUrl=https://www.tcmjc.com/zgzy, iacademicId=null, status=1, seqNo=null, journalTitleEn=Chinese Journal of Traditional Chinese Medicine, journalPhotoCn=Wp+xVi2pFpMjZtgAvUPqBA==, journalPhotoEn=+6LpkbuqcMxcXTbcXC5SRA==, journalFirstLetter=Z, journalRecommend=null, journalNew=null, journalCollection=null, jcrJf=null, cjcrJf=null, jcrJfStr=null, cjcrJfStr=null, submissionFirstDecision=null, sciSubjectClassification=null, casSubjectClassification=null, citeScore=null, totalCitationFrequency=null, icpCode=null, psCode=null, advertisingLicenseCode=null, copyrightInformation=null, country=null, option=, provinceCode=null, provinceName=null, collectFlag=false, interPubPlatform=, interPubPlatformUrl=null), detailUrlCn=https://castjournals.cast.org.cn/joweb/zgzyzz/CN/10.19540/j.cnki.cjcmm.20251009.201, detailUrlEn=https://castjournals.cast.org.cn/joweb/zgzyzz/EN/10.19540/j.cnki.cjcmm.20251009.201, pdfUrlCn=https://castjournals.cast.org.cn/joweb/zgzyzz/CN/PDF/10.19540/j.cnki.cjcmm.20251009.201, pdfUrlEn=https://castjournals.cast.org.cn/joweb/zgzyzz/EN/PDF/10.19540/j.cnki.cjcmm.20251009.201, aliStartDate=null, aliEndDate=null, collectionFlag=false, citedCount=null, citedUrl=null, previewStatus=0, delFlag=0, hasFullText=0, orderTime=1767196800000, fullTextJson=null, articleText=null, reference=null)