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A novel antidepressant toludesvenlafaxine
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Wan-yan ZHOU1, Qin-yu LÜ1, 2, Zheng-hui YI1, 2, 3
Chinese Journal of New Drugs and Clinical Remedies | 2024, 43(7) : 514 - 517
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Chinese Journal of New Drugs and Clinical Remedies | 2024, 43(7): 514-517
New Drug Introduction
A novel antidepressant toludesvenlafaxine
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Wan-yan ZHOU1, Qin-yu LÜ1, 2, Zheng-hui YI1, 2, 3
Affiliations
  • 1.Department of Psychiatry, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, SHANGHAI 200030, China
  • 2.Department of Psychiatry, Huashan Hospital, Fudan University, SHANGHAI 200040, China
  • 3.Institute of Mental Health, Fudan University, SHANGHAI 200040, China
Published: 2024-07-25 doi: 10.14109/j.cnki.xyylc.2024.07.06
Outline
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The new antidepressant toludesvenlafaxine, also known as ansofaxine, is a triple monoaminergic reuptake inhibitor independently developed in China. It can play an antidepressant effects by blocking the reuptake of the three neurotransmitters by combining with the serotonin transporter, noradrenaline, and dopamine transporter. Toludesvenlafaxine has a rapid effect, which can significantly improve the low mood, anhedonia, lack of motivation and other symptoms of patients with depressive disorders, relieve the associated anxiety symptoms, and is not easy to lead to sexual dysfunction and other adverse reactions in the treatment process. While using toludesvenlafaxine, clinicians should start titration with a low dose and assess the risk of mania during the course of treatment, and pay attention to whether the drug could cause psychotic symptoms, since it acts on the dopamine pathway.

toludesvenlafaxine  /  antidepressive agents  /  dopamine uptake inhibitors  /  adrenergic uptake inhibitors
Wan-yan ZHOU, Qin-yu LÜ, Zheng-hui YI. A novel antidepressant toludesvenlafaxine[J]. Chinese Journal of New Drugs and Clinical Remedies, 2024 , 43 (7) : 514 -517 . DOI: 10.14109/j.cnki.xyylc.2024.07.06
Year 2024 volume 43 Issue 7
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Article Info
doi: 10.14109/j.cnki.xyylc.2024.07.06
  • Receive Date:2023-10-26
  • Online Date:2026-03-13
  • Published:2024-07-25
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History
  • Received:2023-10-26
  • Accepted:2024-03-27
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Affiliations
    1.Department of Psychiatry, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, SHANGHAI 200030, China
    2.Department of Psychiatry, Huashan Hospital, Fudan University, SHANGHAI 200040, China
    3.Institute of Mental Health, Fudan University, SHANGHAI 200040, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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