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Research progress on mechanism of aspirin in preventing preeclampsia and drug related gene polymorphism
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Qing HUANG1, 2, Jia QI1
Chinese Journal of New Drugs and Clinical Remedies | 2024, 43(7) : 489 - 494
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Chinese Journal of New Drugs and Clinical Remedies | 2024, 43(7): 489-494
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Research progress on mechanism of aspirin in preventing preeclampsia and drug related gene polymorphism
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Qing HUANG1, 2, Jia QI1
Affiliations
  • 1.Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, SHANGHAI 200092, China
  • 2.School of Pharmacy, Shanghai University of Medicine and Health Science, SHANGHAI 201318, China
Published: 2024-07-25 doi: 10.14109/j.cnki.xyylc.2024.07.02
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Preeclampsia is a common hypertensive disorder of pregnancy, which seriously endangers the health of mothers and infants. The early application of low-dose aspirin can effectively prevent preeclampsia, and effectively reduce the probability of hemolysis, elevated liver function and low platelet count syndrome, placental abruption, and fetal distress. In recent years, with the deepening of research, more experimental evidences show that there is a correlation between gene polymorphisms and aspirin resistance. Because some patients have gene polymorphisms, the expected therapeutic effect cannot be achieved. This paper reviewed the research progress of precision medication of aspirin in high-risk pregnant women with preeclampsia, in order to guide the medication of aspirin in special groups such as pregnant women with preeclampsia and improve pregnancy outcomes.

preeclampsia  /  aspirin  /  aspirin resistance  /  gene polymorphism
Qing HUANG, Jia QI. Research progress on mechanism of aspirin in preventing preeclampsia and drug related gene polymorphism[J]. Chinese Journal of New Drugs and Clinical Remedies, 2024 , 43 (7) : 489 -494 . DOI: 10.14109/j.cnki.xyylc.2024.07.02
Year 2024 volume 43 Issue 7
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Article Info
doi: 10.14109/j.cnki.xyylc.2024.07.02
  • Receive Date:2023-09-26
  • Online Date:2026-03-13
  • Published:2024-07-25
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History
  • Received:2023-09-26
  • Accepted:2024-06-14
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Affiliations
    1.Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, SHANGHAI 200092, China
    2.School of Pharmacy, Shanghai University of Medicine and Health Science, SHANGHAI 201318, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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