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Research progress in antibody-drug conjugates in ovarian cancer
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Mei-ling JING1, Xing YU2
Chinese Journal of New Drugs and Clinical Remedies | 2024, 43(11) : 809 - 813
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Chinese Journal of New Drugs and Clinical Remedies | 2024, 43(11): 809-813
• Review •
Research progress in antibody-drug conjugates in ovarian cancer
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Mei-ling JING1, Xing YU2
Affiliations
  • 1.Medical College, Yanbian University, Yanji JILIN 133002, China
  • 2.Department of Preventive Medicine, Medical College,Yanbian University, Yanji JILIN 133002, China
Published: 2024-11-25 doi: 10.14109/j.cnki.xyylc.2024.11.02
Outline
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Antibody-drug conjugates（ADCs）consist of monoclonal antibodies, linkers, and cytotoxic drugs,representing a novel class of anti-cancer agents that combine target specificity with chemotherapeutic efficacy. ADCs have demonstrated significant efficacy not only in breast cancer, gastric cancer and lung cancer, and have also shown clinical benefits in ovarian cancer. This review discussed the structure, mechanism, and applications of ADCs in ovarian cancer,aiming to provide new insights for clinical treatment of ovarian cancer.

antibody-drug conjuagte  /  targeted therapy  /  ovarian cancer
Mei-ling JING, Xing YU. Research progress in antibody-drug conjugates in ovarian cancer[J]. Chinese Journal of New Drugs and Clinical Remedies, 2024 , 43 (11) : 809 -813 . DOI: 10.14109/j.cnki.xyylc.2024.11.02
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Year 2024 volume 43 Issue 11
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Article Info
doi: 10.14109/j.cnki.xyylc.2024.11.02
  • Receive Date：2024-01-22
  • Online Date：2026-03-13
  • Published：2024-11-25
Article Data
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History
  • Received：2024-01-22
  • Accepted：2024-08-05
Funding
Affiliations
    1.Medical College, Yanbian University, Yanji JILIN 133002, China
    2.Department of Preventive Medicine, Medical College,Yanbian University, Yanji JILIN 133002, China
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多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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