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Carvedilol, a β-blocker with the function of blocking α1 and β adrenoceptors, has been widely used in existing clinical practice for cardio vascular diseases, such as hypertension, chronic heart failure and arrhythmia. In recent years, some clinical researches showed that carvedilol might have some potentially novelty prospect on prevention of atherosclerosis, protection of cardiac function of patients with different complications, improvement of diabetic patients’ ability to regulate blood sugar, and treatment of breast cancer and Alzheimer’s disease. Moreover, with the further study of G protein coupled receptor （GPCR）, the special mechanism of β-arrestin-biased GPCR signal transduction had been found in carvedilol, Which could contribute to its highly selective action on target cells and could reduce the incidence of adverse drug reactions.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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