PDF
Full
Outline
N6-methyladenosine（m6A） methylation is involved in the whole process of mRNA biological behavior and plays an important role in the malignant progression of cancer. This article reviewed the invasion and metastasis of m6A methylation in hepatocellular carcinoma （HCC）, its regulation with non-coding RNA, and the effect of immunotherapy. It is very important to find that m6A methylated regulatory proteins are involved in the development and prognosis of HCC.m6A methylation is closely related to the regulation of non-coding RNA on the proliferation, metastasis and drug resistance of HCC. In terms of immunotherapy, circRHBDD1 and BTBD10 participate in m6A methylation modification to regulate cell metabolism and inhibit the immune escape of cancer cells, which can be used for the HCC diagnosis and innovative drug discovery in the future.
PDF
130
62
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
关闭全屏
No. 86 Xueyuan South Road, Haidian District, Beijing
010-62199257
qkjq@cast.org.cn
Copyright © 2025 China Association for Science and Technology. All rights reserved. For all open access content, the relevant licensing terms apply.
Sponsored by the Office of the Leading Group for Cybersecurity and Informatization of CAST, and supported by Science and Technology Review Publishing House
