Full
Outline
To explore the correlation between traditional Chinese medicine (TCM) constitution and depressive symptom among school-aged children and adolescents, so as to provide evidences for informing constitution-based regulation and prevention of depressive symptom.
From June to December 2024, a total of 4 729 students aged 6-14 were recruited by cluster random sampling from 10 primary schools in Baoding (Hebei Province), Heze and Liaocheng (Shandong Province). General information, TCM constitution and depressive symptom were collected. Restricted cubic spline (RCS) models were used to analyze related factors and threshold effects of depressive symptom. Binary Logistic regression was applied to examine the association between depressive symptom and TCM constitution, with subgroup analyses conducted.
The detection rate of depressive symptom among the included children and adolescents was 25.82%. RCS analyses indicated non-linear associations between depressive symptom and age (inflection point at 10 years old), bedtime (inflection point at 22:00), and wake-up time (inflection point at 6:30) (all Pnon-linearity < 0.01). Linear associations were observed with body mass index (BMI) and sleep duration (all Pnon-linearity>0.05). After adjusting for covariates such as age, BMI and sleep status, binary Logistic regression analyses showed that Yin-deficient constitution (OR=1.26, 95%CI=1.09-1.45) and Phlegm-dampness constitution (OR=1.42, 95%CI=1.11-1.82) were significantly associated with depressive symptom among children and adolescents (all P < 0.05).
Depressive symptom among school-aged children and adolescents is primarily associated with Yin-deficiency and Phlegm-dampness constitutions in TCM constitution. Active attention should be paid to susceptible TCM constitution among children and adolescents. Targeted health guidance and interventions should be implemented to improve TCM constitution health status for preventing the occurrence of depressive symptom.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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