Article(id=1292135430443528881, tenantId=1146029695717560320, journalId=1246415772164075586, issueId=1292135402790482407, articleNumber=null, orderNo=null, doi=10.13699/j.cnki.1001-6821.2026.11.016, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1769443200000, receivedDateStr=2026-01-27, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1785998693332, onlineDateStr=2026-08-06, pubDate=1781625600000, pubDateStr=2026-06-17, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1785998693332, onlineIssueDateStr=2026-08-06, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1785998693332, creator=13701087609, updateTime=1785998693332, updator=13701087609, issue=Issue{id=1292135402790482407, tenantId=1146029695717560320, journalId=1246415772164075586, year='2026', volume='42', issue='11', pageStart='1501', pageEnd='1650', issueExtLink='null', onlineDate='null', pubDate='1781625600000', pubDateStr='2026-06-17', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=1, specialIssue=null, createTime=1785998686739, creator='13701087609', updateTime=1786014315540, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1292200954833686587, tenantId=1146029695717560320, journalId=1246415772164075586, issueId=1292135402790482407, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1292200954833686588, tenantId=1146029695717560320, journalId=1246415772164075586, issueId=1292135402790482407, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=1595, endPage=1601, ext={EN=ArticleExt(id=1292135430678409906, articleId=1292135430443528881, tenantId=1146029695717560320, journalId=1246415772164075586, language=EN, title=Current research status of clinical application of fospropofol disodium, columnId=1246531408630534361, journalTitle=Chinese Journal of Clinical Pharmacology, columnName=Review, runingTitle=null, highlight=null, articleAbstract=

Propofol is one of the most widely used intravenous general anesthetics in clinical practice, mainly due to its rapid onset of action, short half-life period, and high clearance rate. However, propofol is associated with a variety of adverse drug reactions, such as injection site pain, hypotension, respiratory depression, hyperlipidemia, allergies, and propofol infusion syndrome. As a water-soluble prodrug of propofol, fospropofol disodium possesses unique formulation advantages and controllable pharmacological properties, and has been gradually applied in the field of clinical anesthesia. This article aims to systematically review the pharmacological characteristics, clinical research progress, advantages and limitations of fospropofol disodium, and prospect its future application prospects in clinical anesthesia.

, authors=Qing-ran XU, Ce WANG, Yang-yu LI, authorsList=Qing-ran XU, Ce WANG, Yang-yu LI, authorCompany=null, correspAuthors=Yang-yu LI, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1292135430984594099, articleId=1292135430443528881, tenantId=1146029695717560320, journalId=1246415772164075586, language=CN, title=磷丙泊酚二钠的临床应用研究现状, columnId=1246531408819278046, journalTitle=中国临床药理学杂志, columnName=综述, runingTitle=null, highlight=null, articleAbstract=

丙泊酚是目前临床应用最广泛的静脉全身麻醉药之一，主要原因在于其起效迅速、半衰期短且清除率高。然而丙泊酚存在多种药物不良反应，如注射部位疼痛、低血压、呼吸抑制、高脂血症、过敏以及丙泊酚输注综合征等。磷丙泊酚二钠作为丙泊酚的水溶性前体药物，其拥有独特的制剂优势和可控的药理特性，在临床麻醉领域逐渐得到应用。本文旨在系统阐述磷丙泊酚二钠的药理学特性、临床研究进展、优势与局限性，并展望其未来在临床麻醉中的应用前景。

, authors=许青然, 王策, 李阳毓, authorsList=许青然, 王策, 李阳毓, authorCompany=null, correspAuthors=李阳毓, authorNote=, correspAuthorsNote=, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=xMmGJzUFuzrh8KHtxWK0IA==, magXml=0O43KtyjZ7HMzqFB5leBbg==, pdfUrl=null, pdf=K7XVmzODg9b562tZ8tS5Iw==, pdfFileSize=1604009, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=KjkKJIMfiAMXShpuPLsZvQ==, mapNumber=null, fund=null)}, authors=[Author(id=1292135431437578938, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1292135430443528881, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1292135431630516924, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1292135430443528881, authorId=1292135431437578938, language=EN, stringName=Qing-ran XU, firstName=Qing-ran, middleName=null, lastName=XU, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=Department of Anesthesiology, The Fourth Affiliated Hospital of China Medical University, Shenyang 110032, Liaoning Province, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1292135431706014397, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1292135430443528881, authorId=1292135431437578938, language=CN, stringName=许青然, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=中国医科大学 附属第四医院 麻醉科，辽宁 沈阳 110032, bio={"content":"

许青然（2001-），女，硕士研究生，主要从事麻醉药物的药理作用及围术期器官保护方面的研究

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许青然（2001-），女，硕士研究生，主要从事麻醉药物的药理作用及围术期器官保护方面的研究

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