Article(id=1291404846591107144, tenantId=1146029695717560320, journalId=1246415772164075586, issueId=1291404807152067353, articleNumber=null, orderNo=null, doi=10.13699/j.cnki.1001-6821.2025.08.017, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1731686400000, receivedDateStr=2024-11-16, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1785824508568, onlineDateStr=2026-08-04, pubDate=1745769600000, pubDateStr=2025-04-28, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1785824508568, onlineIssueDateStr=2026-08-04, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1785824508568, creator=13701087609, updateTime=1785824508568, updator=13701087609, issue=Issue{id=1291404807152067353, tenantId=1146029695717560320, journalId=1246415772164075586, year='2025', volume='41', issue='8', pageStart='1051', pageEnd='1200', issueExtLink='null', onlineDate='null', pubDate='1745769600000', pubDateStr='2025-04-28', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1785824499166, creator='13701087609', updateTime=1785824499166, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext=null, issueFiles=null, downloadFileDto=null}, startPage=1144, endPage=1151, ext={EN=ArticleExt(id=1291404846821793866, articleId=1291404846591107144, tenantId=1146029695717560320, journalId=1246415772164075586, language=EN, title=Surveillance of antimicrobial resistance among bacterial strains isolated from a Northwest tertiary teaching hospital in 2021—2023, columnId=1291404846742102089, journalTitle=Chinese Journal of Clinical Pharmacology, columnName=Bacterial Resistance Surveillance, runingTitle=null, highlight=null, articleAbstract=
Objective To analyze the antimicrobial sensitivity against clinical isolates in the first affiliated hospital of air force medical university in the past three years.
Methods The nonduplicate clinical isolates were collected in 2021—2023, identification and drug sensitivity test were performed by using VITEK2-compact automatic bacteria identification system. The data was analyzed using WHONET 5.6 software and interpreted according to the Clinical and Laboratory Standards Institute (CLSI) 2023 breakpoints.
Results A total of 20 536 clinical isolates were collected, of which 28.78% were gram-positive, 58.64% were gram-negative, 11.94% were fungi and 0.64% were anaerobe. The prevalence of methicillin-resistant strains in Staphylococcus aureus and coagulase-negative Staphylococcus were 49.11% and 73.06%, respectively. No Staphylococcus resistant to vancomycin, linezolid, or tigecycline was detected. The resistance rates of Enterococcus faecium to most antimicrobial agents were much higher than Enterococcus faecalis. 8 strains of vancomycin-resistant Enterococcus faecium were isolated, and a few linezolid-resistant strains were identiffed in both species. The prevalence of penicillin-susceptible Streptococcus pneumoniae (PSSP) was 95.85%. The resistance rate to carbapenems was 0.2% to 12.8% in Enterobacterales species, and the detection rate of carbapenem-resistant Enterobacteriaceae (CRE) was 6.6%, with Klebsiella pneumoniae accounting for 66.53%. The resistance rates of Acinetobacter spp to imipenem and meropenem were 75.3% and 76.7%, respectively. Meanwhile, the rates of Pseudomonas aeruginosa were 22.9% and 19.9% respectively.
Conclusion The antimicrobial resistance of clinical isolates in our hospital is still serious. All relevant departments should strengthen the monitoring of bacterial resistance in order to curb the development and spread of bacterial resistance.
, authors=Shan ZHOU, Hao LIU, Mei-juan KONG, Bei-pei KANG, Lu BAI, Ke ZHOU, Jia-yun LIU, authorsList=Shan ZHOU, Hao LIU, Mei-juan KONG, Bei-pei KANG, Lu BAI, Ke ZHOU, Jia-yun LIU, authorCompany=null, correspAuthors=Jia-yun LIU, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1291404847258001484, articleId=1291404846591107144, tenantId=1146029695717560320, journalId=1246415772164075586, language=CN, title=2021—2023年西北地区某三甲医院临床病原菌分离及耐药性监测, columnId=1291404846905679947, journalTitle=中国临床药理学杂志, columnName=细菌耐药监测, runingTitle=null, highlight=null, articleAbstract=
目的 分析空军军医大学第一附属医院近3年临床菌株分布及其对抗菌药物的敏感性。
方法 收集2021—2023年临床分离非重复菌株，用VITEK2-compact全自动细菌鉴定仪对细菌进行鉴定及药物敏感性试验。按2023年美国临床和实验室标准协会（CLSI）文件标准判读结果，用WHONET 5.6软件进行统计分析。
结果 共分离菌株20 536株，其中，革兰氏阳性菌占28.78%、革兰氏阴性菌占58.64%、真菌占11.94%、厌氧菌占0.64%。金黄色葡萄球菌、凝固酶阴性葡萄球菌中甲氧西林耐药株的检出率分别为49.11%和73.06%，未发现对万古霉素、利奈唑胺、替加环素耐药的葡萄球菌。屎肠球菌对多数抗菌药物耐药率明显高于粪肠球菌，分离出8株万古霉素耐药屎肠球菌，两者中均有少数利奈唑胺耐药株。肺炎链球菌中青霉素敏感肺炎链球菌（PSSP）的检出率为95.85%。肠杆菌目细菌碳青霉烯类耐药率范围为0.2%~12.8%，碳青霉烯类耐药肠杆菌目细菌（CRE）的检出率为6.6%，其中主要为肺炎克雷伯菌占66.53%。不动杆菌属对亚胺培南和美罗培南的耐药率分别为75.3%和76.7%，铜绿假单胞菌对两药耐药率分别为22.9%和19.9%。
结论 我院临床菌株耐药形势仍较严峻，医院各相关部门应加强细菌耐药监测，以遏制细菌耐药的发展和传播。
, authors=周珊, 刘昊, 孔美娟, 康蓓佩, 白露, 周柯, 刘家云, authorsList=周珊, 刘昊, 孔美娟, 康蓓佩, 白露, 周柯, 刘家云, authorCompany=null, correspAuthors=刘家云, authorNote=
周珊（1984-），女，副主任医师，主要从事细菌耐药性监测及耐药机制的相关研究
, correspAuthorsNote=
, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=fRNwKJVMomRQTYHW2Di+vA==, magXml=sdzAnkvZXMqIrVWpMyHTDA==, pdfUrl=null, pdf=q4LKh27f6dvUM1L3b6h7sw==, pdfFileSize=1466124, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=Nb+NjWNmxzNXBFanqiFmPg==, mapNumber=null, fund=null)}, authors=[Author(id=1291404847576768594, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1291404847643877460, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, authorId=1291404847576768594, language=EN, stringName=Shan ZHOU, firstName=Shan, middleName=null, lastName=ZHOU, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=Department of Clinical Laboratory, The First Affiliated Hospital of Air Force Medical University, Xi’an 710032, Shaanxi Province, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1291404847710986325, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, authorId=1291404847576768594, language=CN, stringName=周珊, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=空军军医大学 第一附属医院 检验科，陕西 西安 710032, bio={"content":"
周珊（1984-），女，副主任医师，主要从事细菌耐药性监测及耐药机制的相关研究
"}, bioImg=null, bioContent=
周珊（1984-），女，副主任医师，主要从事细菌耐药性监测及耐药机制的相关研究
, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1291404847476105294, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, xref=null, ext=[AuthorCompanyExt(id=1291404847484493903, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, companyId=1291404847476105294, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=Department of Clinical Laboratory, The First Affiliated Hospital of Air Force Medical University, Xi’an 710032, Shaanxi Province, China), AuthorCompanyExt(id=1291404847497076816, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, companyId=1291404847476105294, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=空军军医大学 第一附属医院 检验科，陕西 西安 710032)])]), Author(id=1291404847778095191, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, orderNo=1, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1291404847878758489, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, authorId=1291404847778095191, language=EN, stringName=Hao LIU, firstName=Hao, middleName=null, lastName=LIU, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=Department of Clinical Laboratory, The First Affiliated Hospital of Air Force Medical University, Xi’an 710032, Shaanxi Province, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1291404847954255962, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, authorId=1291404847778095191, language=CN, stringName=刘昊, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=空军军医大学 第一附属医院 检验科，陕西 西安 710032, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1291404847476105294, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, xref=null, ext=[AuthorCompanyExt(id=1291404847484493903, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, companyId=1291404847476105294, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=Department of Clinical Laboratory, The First Affiliated Hospital of Air Force Medical University, Xi’an 710032, Shaanxi Province, China), AuthorCompanyExt(id=1291404847497076816, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, companyId=1291404847476105294, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=空军军医大学 第一附属医院 检验科，陕西 西安 710032)])]), Author(id=1291404848029753436, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, orderNo=2, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1291404848101056606, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, authorId=1291404848029753436, language=EN, stringName=Mei-juan KONG, firstName=Mei-juan, middleName=null, lastName=KONG, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=Department of Clinical Laboratory, The First Affiliated Hospital of Air Force Medical University, Xi’an 710032, Shaanxi Province, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1291404848176554079, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, authorId=1291404848029753436, language=CN, stringName=孔美娟, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=空军军医大学 第一附属医院 检验科，陕西 西安 710032, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1291404847476105294, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, xref=null, ext=[AuthorCompanyExt(id=1291404847484493903, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, companyId=1291404847476105294, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=Department of Clinical Laboratory, The First Affiliated Hospital of Air Force Medical University, Xi’an 710032, Shaanxi Province, China), AuthorCompanyExt(id=1291404847497076816, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, companyId=1291404847476105294, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=空军军医大学 第一附属医院 检验科，陕西 西安 710032)])]), Author(id=1291404848243662945, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, orderNo=3, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1291404848344326243, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, authorId=1291404848243662945, language=EN, stringName=Bei-pei KANG, firstName=Bei-pei, middleName=null, lastName=KANG, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=Department of Clinical Laboratory, The First Affiliated Hospital of Air Force Medical University, Xi’an 710032, Shaanxi Province, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1291404848407240804, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, authorId=1291404848243662945, language=CN, stringName=康蓓佩, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=空军军医大学 第一附属医院 检验科，陕西 西安 710032, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1291404847476105294, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, xref=null, ext=[AuthorCompanyExt(id=1291404847484493903, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, companyId=1291404847476105294, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=Department of Clinical Laboratory, The First Affiliated Hospital of Air Force Medical University, Xi’an 710032, Shaanxi Province, China), AuthorCompanyExt(id=1291404847497076816, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, companyId=1291404847476105294, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=空军军医大学 第一附属医院 检验科，陕西 西安 710032)])]), Author(id=1291404848474349670, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, orderNo=4, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1291404850143682664, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, authorId=1291404848474349670, language=EN, stringName=Lu BAI, firstName=Lu, middleName=null, lastName=BAI, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=Department of Clinical Laboratory, The First Affiliated Hospital of Air Force Medical University, Xi’an 710032, Shaanxi Province, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1291404850235957353, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, authorId=1291404848474349670, language=CN, stringName=白露, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=空军军医大学 第一附属医院 检验科，陕西 西安 710032, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1291404847476105294, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, xref=null, ext=[AuthorCompanyExt(id=1291404847484493903, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, companyId=1291404847476105294, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=Department of Clinical Laboratory, The First Affiliated Hospital of Air Force Medical University, Xi’an 710032, Shaanxi Province, China), AuthorCompanyExt(id=1291404847497076816, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, companyId=1291404847476105294, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=空军军医大学 第一附属医院 检验科，陕西 西安 710032)])]), Author(id=1291404850353397867, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, orderNo=5, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1291404850433089645, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, authorId=1291404850353397867, language=EN, stringName=Ke ZHOU, firstName=Ke, middleName=null, lastName=ZHOU, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=Department of Clinical Laboratory, The First Affiliated Hospital of Air Force Medical University, Xi’an 710032, Shaanxi Province, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1291404850521170030, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, authorId=1291404850353397867, language=CN, stringName=周柯, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=空军军医大学 第一附属医院 检验科，陕西 西安 710032, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1291404847476105294, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, xref=null, ext=[AuthorCompanyExt(id=1291404847484493903, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, companyId=1291404847476105294, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=Department of Clinical Laboratory, The First Affiliated Hospital of Air Force Medical University, Xi’an 710032, Shaanxi Province, China), AuthorCompanyExt(id=1291404847497076816, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, companyId=1291404847476105294, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=空军军医大学 第一附属医院 检验科，陕西 西安 710032)])]), Author(id=1291404850588278896, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, orderNo=6, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=jiayun@fmmu.edu.cn, emailSecond=null, emailThird=null, correspondingAuthor=1, authorType=1, ext={EN=AuthorExt(id=1291404850688942194, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, authorId=1291404850588278896, language=EN, stringName=Jia-yun LIU, firstName=Jia-yun, middleName=null, lastName=LIU, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=Department of Clinical Laboratory, The First Affiliated Hospital of Air Force Medical University, Xi’an 710032, Shaanxi Province, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1291404850785411187, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, authorId=1291404850588278896, language=CN, stringName=刘家云, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=空军军医大学 第一附属医院 检验科，陕西 西安 710032, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1291404847476105294, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, xref=null, ext=[AuthorCompanyExt(id=1291404847484493903, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, companyId=1291404847476105294, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=Department of Clinical Laboratory, The First Affiliated Hospital of Air Force Medical University, Xi’an 710032, Shaanxi Province, China), AuthorCompanyExt(id=1291404847497076816, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, companyId=1291404847476105294, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=空军军医大学 第一附属医院 检验科，陕西 西安 710032)])])], keywords=[Keyword(id=1291404850881880180, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, language=EN, orderNo=1, keyword=antimicrobial resistance surveillance), Keyword(id=1291404850944794741, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, language=EN, orderNo=2, keyword=pathogenic bacteria), Keyword(id=1291404851016097910, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, language=EN, orderNo=3, keyword=resistance), Keyword(id=1291404851099983991, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, language=EN, orderNo=4, keyword=epidemiology), Keyword(id=1291404851167092856, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, language=CN, orderNo=1, keyword=细菌耐药监测), Keyword(id=1291404851230007417, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, language=CN, orderNo=2, keyword=病原菌), Keyword(id=1291404851347447930, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, language=CN, orderNo=3, keyword=耐药性), Keyword(id=1291404851427139707, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, language=CN, orderNo=4, keyword=流行病学)], refs=null, funds=[Fund(id=1291404851523608700, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, awardId=2020JQ-459, language=CN, fundingSource=陕西省自然科学基金资助项目(2020JQ-459), fundOrder=null, country=null)], companyList=[AuthorCompany(id=1291404847476105294, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, xref=null, ext=[AuthorCompanyExt(id=1291404847484493903, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, companyId=1291404847476105294, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=Department of Clinical Laboratory, The First Affiliated Hospital of Air Force Medical University, Xi’an 710032, Shaanxi Province, China), AuthorCompanyExt(id=1291404847497076816, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404846591107144, companyId=1291404847476105294, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=空军军医大学 第一附属医院 检验科，陕西 西安 710032)])], figs=null, attaches=null, journal=Journal(id=1246415058658443328, delFlag=0, nameCn=中国临床药理学杂志, nameEn=Chinese Journal of Clinical Pharmacology, nameHistory1=null, nameHistory2=null, issn=1001-6821, eissn=null, cn=11-2220/R, coden=null, periodic=3, language=CN, oaType=null, ccby=null, superviseOffice=null, ownerOffice=null, pubOffice=null, editorOffice=null, officeType=null, aims=null, clcCode=null, officeProv=null, officeCity=null, officeAddr=null, officeZip=null, officeEmail=null, officePhone=null, editDirector=null, officeDirector=null, officeDirectorPhone=null, officeStaffNum=null, officeEmpNum=null, coverPicUrl=8cEfS7jvj/ukyhKVOMJePA==, journalPrice=null, startedYear=null, abbrevIsoEn=Chinese Journal of Clinical Pharmacology, journalRemark=null, publicationField=null, createdTime=1775098107259, updatedTime=1784020014723, createdBy=18614031015, updatedBy=13041195026, firstLetterCn=Z, firstLetterEn=Z, subjectCode=Life Sciences, subjectName=null, subjectCodeEn=Life Sciences, subjectNameEn=null, picCn=8cEfS7jvj/ukyhKVOMJePA==, picEn=cQ12tu98gbNetbFuefeYGg==, jcr=null, cjcr=null, exts=[JournalExt(id=1283836250926859016, language=CN, name=中国临床药理学杂志, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1784020014745, updatedTime=1784020014745, createdBy=13041195026, updatedBy=13041195026, submissionGuidelinesUrl=, submissionAuthorUrl=https://lcylauthor.cast.org.cn/webm, submissionEditorUrl=https://lcyleditor.cast.org.cn/webm, submissionReviewUrl=https://lcylauthor.cast.org.cn/webm, submissionCeEditorUrl=https://lcyleditor.cast.org.cn/webm, submissionAeEditorUrl=https://lcyleditor.cast.org.cn/webm, option={"copyright":""}), JournalExt(id=1283836250981384969, language=EN, name=Chinese Journal of Clinical Pharmacology, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1784020014758, updatedTime=1784020014758, createdBy=13041195026, updatedBy=13041195026, submissionGuidelinesUrl=, submissionAuthorUrl=https://lcylauthor.cast.org.cn/webm, submissionEditorUrl=https://lcyleditor.cast.org.cn/webm, submissionReviewUrl=https://lcylauthor.cast.org.cn/webm, submissionCeEditorUrl=https://lcyleditor.cast.org.cn/webm, submissionAeEditorUrl=https://lcyleditor.cast.org.cn/webm, option={"copyright":""})], databaseList=null, tenantJournalId=1246415772164075586, websiteList=[Website(id=1246421196657546140, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1246415772164075586, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/zglcylxzz/CN, language=CN, createTime=1775099570670, createBy=18614031015, updateTime=1775099747371, updateBy=18614031015, name=中国临床药理学杂志-中文, tplId=1146099689490845704, title=中国临床药理学杂志, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1246422027293316008, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1246421196657546140, code=articleTextType, value=kx, createTime=1775099768708, updateTime=1775099768708, creator=18614031015, updator=18614031015), WebsiteProps(id=1246422027268150181, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1246421196657546140, code=banner, value=null, createTime=1775099768702, updateTime=1775099768702, creator=18614031015, updator=18614031015), WebsiteProps(id=1246422027310093227, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1246421196657546140, code=grayFlag, value=0, createTime=1775099768712, updateTime=1775099768712, creator=18614031015, updator=18614031015), WebsiteProps(id=1246422027259761572, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1246421196657546140, code=logo, value=https://castjournals.cast.org.cn/joweb/zglcylxzz/CN/file/pic?fileId=KeUk4pyVjfIIkOq40uZX0Q==, createTime=1775099768700, updateTime=1775099768700, creator=18614031015, updator=18614031015), WebsiteProps(id=1246422027322676141, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1246421196657546140, code=minRunFlag, value=0, createTime=1775099768715, updateTime=1775099768715, creator=18614031015, updator=18614031015), WebsiteProps(id=1246422027284927399, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1246421196657546140, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/zglcylxzz/CN/file/pic, createTime=1775099768706, updateTime=1775099768706, creator=18614031015, updator=18614031015), WebsiteProps(id=1246422027318481836, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1246421196657546140, code=silenceFlag, value=0, createTime=1775099768714, updateTime=1775099768714, creator=18614031015, updator=18614031015), WebsiteProps(id=1246422027276538790, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1246421196657546140, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_cn_619/, createTime=1775099768704, updateTime=1775099768704, creator=18614031015, updator=18614031015), WebsiteProps(id=1246422027297510313, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1246421196657546140, code=themeColor, value=null, createTime=1775099768709, updateTime=1775099768709, creator=18614031015, updator=18614031015), WebsiteProps(id=1246422027305898922, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1246421196657546140, code=themeStyle, value=null, createTime=1775099768711, updateTime=1775099768711, creator=18614031015, updator=18614031015)]), Website(id=1246421196871455649, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1246415772164075586, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/zglcylxzz/EN, language=EN, createTime=1775099570720, createBy=18614031015, updateTime=1775099757298, updateBy=18614031015, name=中国临床药理学杂志-英文, tplId=1146101810881728533, title=Chinese Journal of Clinical Pharmacology, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1246422058998059954, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1246421196871455649, code=articleTextType, value=kx, createTime=1775099776267, updateTime=1775099776267, creator=18614031015, updator=18614031015), WebsiteProps(id=1246422058977088431, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1246421196871455649, code=banner, value=null, createTime=1775099776262, updateTime=1775099776262, creator=18614031015, updator=18614031015), WebsiteProps(id=1246422059014837173, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1246421196871455649, code=grayFlag, value=0, createTime=1775099776271, updateTime=1775099776271, creator=18614031015, updator=18614031015), WebsiteProps(id=1246422058968699822, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1246421196871455649, code=logo, value=https://castjournals.cast.org.cn/joweb/zglcylxzz/EN/file/pic?fileId=KeUk4pyVjfIIkOq40uZX0Q==, createTime=1775099776260, updateTime=1775099776260, creator=18614031015, updator=18614031015), WebsiteProps(id=1246422059031614391, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1246421196871455649, code=minRunFlag, value=0, createTime=1775099776275, updateTime=1775099776275, creator=18614031015, updator=18614031015), WebsiteProps(id=1246422058993865649, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1246421196871455649, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/zglcylxzz/EN/file/pic, createTime=1775099776266, updateTime=1775099776266, creator=18614031015, updator=18614031015), WebsiteProps(id=1246422059023225782, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1246421196871455649, code=silenceFlag, value=0, createTime=1775099776273, updateTime=1775099776273, creator=18614031015, updator=18614031015), WebsiteProps(id=1246422058985477040, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1246421196871455649, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_en_623/, createTime=1775099776264, updateTime=1775099776264, creator=18614031015, updator=18614031015), WebsiteProps(id=1246422059002254259, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1246421196871455649, code=themeColor, value=null, createTime=1775099776268, updateTime=1775099776268, creator=18614031015, updator=18614031015), WebsiteProps(id=1246422059010642868, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1246421196871455649, code=themeStyle, value=null, createTime=1775099776270, updateTime=1775099776270, creator=18614031015, updator=18614031015)])], journalTitle=中国临床药理学杂志, weixinUrl=null, journalUrl=null, iacademicId=null, status=1, seqNo=null, journalTitleEn=Chinese Journal of Clinical Pharmacology, journalPhotoCn=8cEfS7jvj/ukyhKVOMJePA==, journalPhotoEn=cQ12tu98gbNetbFuefeYGg==, journalFirstLetter=Z, journalRecommend=null, journalNew=null, journalCollection=null, jcrJf=null, cjcrJf=null, jcrJfStr=null, cjcrJfStr=null, submissionFirstDecision=null, sciSubjectClassification=null, casSubjectClassification=null, citeScore=null, totalCitationFrequency=null, icpCode=null, psCode=null, advertisingLicenseCode=null, copyrightInformation=null, country=null, option=, provinceCode=null, provinceName=null, collectFlag=false, interPubPlatform=, interPubPlatformUrl=null), detailUrlCn=https://castjournals.cast.org.cn/joweb/zglcylxzz/CN/10.13699/j.cnki.1001-6821.2025.08.017, detailUrlEn=https://castjournals.cast.org.cn/joweb/zglcylxzz/EN/10.13699/j.cnki.1001-6821.2025.08.017, pdfUrlCn=https://castjournals.cast.org.cn/joweb/zglcylxzz/CN/PDF/10.13699/j.cnki.1001-6821.2025.08.017, pdfUrlEn=https://castjournals.cast.org.cn/joweb/zglcylxzz/EN/PDF/10.13699/j.cnki.1001-6821.2025.08.017, aliStartDate=0, aliEndDate=0, collectionFlag=false, citedCount=null, citedUrl=null, previewStatus=0, delFlag=0, hasFullText=0, orderTime=1745769600000, fullTextJson=null, articleText=null, reference=null)
全屏
文章导航
PDF下载
3
1
关闭全屏
北京市海淀区学院南路86号
010-62199257（仅加盟咨询）
qkjq@cast.org.cn
