Article(id=1291339276323643957, tenantId=1146029695717560320, journalId=1246415772164075586, issueId=1291339070622396983, articleNumber=null, orderNo=null, doi=10.13699/j.cnki.1001-6821.2025.03.027, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1722182400000, receivedDateStr=2024-07-29, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1785808875398, onlineDateStr=2026-08-04, pubDate=1739721600000, pubDateStr=2025-02-17, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1785808875398, onlineIssueDateStr=2026-08-04, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1785808875398, creator=13041195026, updateTime=1785808875398, updator=13041195026, issue=Issue{id=1291339070622396983, tenantId=1146029695717560320, journalId=1246415772164075586, year='2025', volume='41', issue='3', pageStart='301', pageEnd='450', issueExtLink='null', onlineDate='null', pubDate='1739721600000', pubDateStr='2025-02-17', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1785808826353, creator='13041195026', updateTime=1785808826353, updator='13041195026', preIssue=null, nextIssue=null, articleTotal=null, ext=null, issueFiles=null, downloadFileDto=null}, startPage=433, endPage=437, ext={EN=ArticleExt(id=1291339276541747766, articleId=1291339276323643957, tenantId=1146029695717560320, journalId=1246415772164075586, language=EN, title=Research status of the modulation of TRPV1 signaling pathway and related factors by traditional Chinese medicine for the treatment of herpes zoster and postherpetic neuralgia, columnId=1246531408630534361, journalTitle=Chinese Journal of Clinical Pharmacology, columnName=Review, runingTitle=null, highlight=null, articleAbstract=
The transient receptor potential vanilloid subtype 1 (TRPV1) signaling pathway is closely related to herpes zoster (HZ) and postherpetic neuralgia (PHN). Traditional Chinese medicine (TCM) has been involved in regulating the TRPV1 signaling pathway in several ways, and has been used to treat HZ and PHN by modulating the aberrant release of TRPV1-associated neuropeptides and inflammatory factors, and neurogenic inflammatory response, etc. This paper summarizes the mechanism and role of TCM in regulating TRPV1 signaling pathway in the treatment of HZ and PHN in recent years, which will provide new ideas for the treatment of HZ and PHN and drug development.
, authors=Xiao-tao XIE
1, Fan-qi NIU
1, Yu-jing PAN
1, Shi-ye HE
1, Si-nong WANG
1, Wen-li ZHOU
2, authorsList=Xiao-tao XIE, Fan-qi NIU, Yu-jing PAN, Shi-ye HE, Si-nong WANG, Wen-li ZHOU, authorCompany=null, correspAuthors=Si-nong WANG, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1291339276936012343, articleId=1291339276323643957, tenantId=1146029695717560320, journalId=1246415772164075586, language=CN, title=中医药调控TRPV1信号通路和相关因子防治带状疱疹及后遗神经痛的研究现状, columnId=1246531408819278046, journalTitle=中国临床药理学杂志, columnName=综述, runingTitle=null, highlight=null, articleAbstract=
瞬时受体电位香草酸亚型1(TRPV1)信号通路与带状疱疹(HZ)及带状疱疹后遗神经痛(PHN)的关系密切。中医药在多个方面参与调控TRPV1信号通路,通过调控TRPV1相关神经肽及炎性因子异常释放,神经源性炎症反应等方面治疗HZ及PHN。本文对近年来中医药调控TRPV1信号通路治疗HZ及PHN的机制和作用进行总结,旨在为HZ及PHN的治疗和药物研发提供新思路。
, authors=谢小涛
1, 牛凡琪
1, 潘钰晶
1, 何世烨
1, 王思农
1, 周文丽
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谢小涛(1998-),男,硕士研究生,主要从事中医药治疗皮肤病的临床与实验研究
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