Article(id=1291339276323643957, tenantId=1146029695717560320, journalId=1246415772164075586, issueId=1291339070622396983, articleNumber=null, orderNo=null, doi=10.13699/j.cnki.1001-6821.2025.03.027, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1722182400000, receivedDateStr=2024-07-29, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1785808875398, onlineDateStr=2026-08-04, pubDate=1739721600000, pubDateStr=2025-02-17, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1785808875398, onlineIssueDateStr=2026-08-04, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1785808875398, creator=13041195026, updateTime=1785808875398, updator=13041195026, issue=Issue{id=1291339070622396983, tenantId=1146029695717560320, journalId=1246415772164075586, year='2025', volume='41', issue='3', pageStart='301', pageEnd='450', issueExtLink='null', onlineDate='null', pubDate='1739721600000', pubDateStr='2025-02-17', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1785808826353, creator='13041195026', updateTime=1785808826353, updator='13041195026', preIssue=null, nextIssue=null, articleTotal=null, ext=null, issueFiles=null, downloadFileDto=null}, startPage=433, endPage=437, ext={EN=ArticleExt(id=1291339276541747766, articleId=1291339276323643957, tenantId=1146029695717560320, journalId=1246415772164075586, language=EN, title=Research status of the modulation of TRPV1 signaling pathway and related factors by traditional Chinese medicine for the treatment of herpes zoster and postherpetic neuralgia, columnId=1246531408630534361, journalTitle=Chinese Journal of Clinical Pharmacology, columnName=Review, runingTitle=null, highlight=null, articleAbstract=

The transient receptor potential vanilloid subtype 1 (TRPV1) signaling pathway is closely related to herpes zoster (HZ) and postherpetic neuralgia (PHN). Traditional Chinese medicine (TCM) has been involved in regulating the TRPV1 signaling pathway in several ways, and has been used to treat HZ and PHN by modulating the aberrant release of TRPV1-associated neuropeptides and inflammatory factors, and neurogenic inflammatory response, etc. This paper summarizes the mechanism and role of TCM in regulating TRPV1 signaling pathway in the treatment of HZ and PHN in recent years, which will provide new ideas for the treatment of HZ and PHN and drug development.

, authors=Xiao-tao XIE1, Fan-qi NIU1, Yu-jing PAN1, Shi-ye HE1, Si-nong WANG1, Wen-li ZHOU2, authorsList=Xiao-tao XIE, Fan-qi NIU, Yu-jing PAN, Shi-ye HE, Si-nong WANG, Wen-li ZHOU, authorCompany=null, correspAuthors=Si-nong WANG, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1291339276936012343, articleId=1291339276323643957, tenantId=1146029695717560320, journalId=1246415772164075586, language=CN, title=中医药调控TRPV1信号通路和相关因子防治带状疱疹及后遗神经痛的研究现状, columnId=1246531408819278046, journalTitle=中国临床药理学杂志, columnName=综述, runingTitle=null, highlight=null, articleAbstract=

瞬时受体电位香草酸亚型1(TRPV1)信号通路与带状疱疹(HZ)及带状疱疹后遗神经痛(PHN)的关系密切。中医药在多个方面参与调控TRPV1信号通路,通过调控TRPV1相关神经肽及炎性因子异常释放,神经源性炎症反应等方面治疗HZ及PHN。本文对近年来中医药调控TRPV1信号通路治疗HZ及PHN的机制和作用进行总结,旨在为HZ及PHN的治疗和药物研发提供新思路。

, authors=谢小涛1, 牛凡琪1, 潘钰晶1, 何世烨1, 王思农1, 周文丽2, authorsList=谢小涛, 牛凡琪, 潘钰晶, 何世烨, 王思农, 周文丽, authorCompany=null, correspAuthors=王思农, authorNote=

谢小涛(1998-),男,硕士研究生,主要从事中医药治疗皮肤病的临床与实验研究

, correspAuthorsNote=
王思农,教授,博士生导师 MP: 15095319507 E-mail:
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中医药调控TRPV1信号通路和相关因子防治带状疱疹及后遗神经痛的研究现状
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谢小涛 1 , 牛凡琪 1 , 潘钰晶 1 , 何世烨 1 , 王思农 1 , 周文丽 2
中国临床药理学杂志 | 综述 2025,41(3): 433-437
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中国临床药理学杂志 |综述 2025 , 41 (3) : 433 -437
中医药调控TRPV1信号通路和相关因子防治带状疱疹及后遗神经痛的研究现状
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谢小涛1, 牛凡琪1, 潘钰晶1, 何世烨1, 王思农1 , 周文丽2
作者信息
  • 1.甘肃中医药大学 中医临床学院,甘肃 兰州 730000
  • 2.甘肃中医药大学 附属医院 皮肤科,甘肃 兰州 730000
通讯作者:
王思农,教授,博士生导师 MP: 15095319507 E-mail:
作者简介:

谢小涛(1998-),男,硕士研究生,主要从事中医药治疗皮肤病的临床与实验研究

Research status of the modulation of TRPV1 signaling pathway and related factors by traditional Chinese medicine for the treatment of herpes zoster and postherpetic neuralgia
Xiao-tao XIE1, Fan-qi NIU1, Yu-jing PAN1, Shi-ye HE1, Si-nong WANG1 , Wen-li ZHOU2
Affiliations
  • 1.School of Clinical Chinese Medicine, Gansu University of Chinese Medicine, Lanzhou 730000, Gansu Province, China
  • 2.Department of Dermatology, Affiliated Hospital of Gansu University of Chinese Medicine, Lanzhou 730000, Gansu Province, China
出版时间: 2025-02-17 doi: 10.13699/j.cnki.1001-6821.2025.03.027
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瞬时受体电位香草酸亚型1(TRPV1)信号通路与带状疱疹(HZ)及带状疱疹后遗神经痛(PHN)的关系密切。中医药在多个方面参与调控TRPV1信号通路,通过调控TRPV1相关神经肽及炎性因子异常释放,神经源性炎症反应等方面治疗HZ及PHN。本文对近年来中医药调控TRPV1信号通路治疗HZ及PHN的机制和作用进行总结,旨在为HZ及PHN的治疗和药物研发提供新思路。

中医药  /  带状疱疹及后遗神经痛  /  瞬时受体电位香草酸亚型1  /  炎症因子  /  皮肤神经源性炎症

The transient receptor potential vanilloid subtype 1 (TRPV1) signaling pathway is closely related to herpes zoster (HZ) and postherpetic neuralgia (PHN). Traditional Chinese medicine (TCM) has been involved in regulating the TRPV1 signaling pathway in several ways, and has been used to treat HZ and PHN by modulating the aberrant release of TRPV1-associated neuropeptides and inflammatory factors, and neurogenic inflammatory response, etc. This paper summarizes the mechanism and role of TCM in regulating TRPV1 signaling pathway in the treatment of HZ and PHN in recent years, which will provide new ideas for the treatment of HZ and PHN and drug development.

traditional Chinese medicine  /  herpes zoster and postherpetic neuralgia  /  transient receptor potential vanilloid subtype 1  /  inflammatory factor  /  neurogenic inflammation of the skin
谢小涛, 牛凡琪, 潘钰晶, 何世烨, 王思农, 周文丽. 中医药调控TRPV1信号通路和相关因子防治带状疱疹及后遗神经痛的研究现状. 中国临床药理学杂志, 2025 , 41 (3) : 433 -437 . DOI: 10.13699/j.cnki.1001-6821.2025.03.027
Xiao-tao XIE, Fan-qi NIU, Yu-jing PAN, Shi-ye HE, Si-nong WANG, Wen-li ZHOU. Research status of the modulation of TRPV1 signaling pathway and related factors by traditional Chinese medicine for the treatment of herpes zoster and postherpetic neuralgia[J]. Chinese Journal of Clinical Pharmacology, 2025 , 41 (3) : 433 -437 . DOI: 10.13699/j.cnki.1001-6821.2025.03.027
  • 国家重点研发计划“中医药现代化研究”重点专项基金资助项目(2018YFC1705301; 2018YFC1705302)
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doi: 10.13699/j.cnki.1001-6821.2025.03.027
  • 接收时间:2024-07-29
  • 首发时间:2026-08-04
  • 出版时间:2025-02-17
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  • 收稿日期:2024-07-29
基金
国家重点研发计划“中医药现代化研究”重点专项基金资助项目(2018YFC1705301; 2018YFC1705302)
作者信息
    1.甘肃中医药大学 中医临床学院,甘肃 兰州 730000
    2.甘肃中医药大学 附属医院 皮肤科,甘肃 兰州 730000

通讯作者:

王思农,教授,博士生导师 MP: 15095319507 E-mail:
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2种不同金属材料的力学参数

Family
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Number of
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种数
Number of
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Percentage of
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Genus
种数
Number of
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Percentage of total
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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