Article(id=1291339117946725270, tenantId=1146029695717560320, journalId=1246415772164075586, issueId=1291339021272211834, articleNumber=null, orderNo=null, doi=10.13699/j.cnki.1001-6821.2025.02.026, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1720972800000, receivedDateStr=2024-07-15, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1785808837638, onlineDateStr=2026-08-04, pubDate=1737993600000, pubDateStr=2025-01-28, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1785808837638, onlineIssueDateStr=2026-08-04, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1785808837638, creator=13041195026, updateTime=1785808837638, updator=13041195026, issue=Issue{id=1291339021272211834, tenantId=1146029695717560320, journalId=1246415772164075586, year='2025', volume='41', issue='2', pageStart='151', pageEnd='300', issueExtLink='null', onlineDate='null', pubDate='1737993600000', pubDateStr='2025-01-28', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1785808814590, creator='13041195026', updateTime=1785808814590, updator='13041195026', preIssue=null, nextIssue=null, articleTotal=null, ext=null, issueFiles=null, downloadFileDto=null}, startPage=279, endPage=283, ext={EN=ArticleExt(id=1291339118701699991, articleId=1291339117946725270, tenantId=1146029695717560320, journalId=1246415772164075586, language=EN, title=Relationship between exosomes and the tumour microenvironment and the impact of their delivery of non-coding RNAs on breast cancer, columnId=1246531408630534361, journalTitle=Chinese Journal of Clinical Pharmacology, columnName=Review, runingTitle=null, highlight=null, articleAbstract=

The development of breast cancer is closely related to the information transfer in its microenvironment. As a novel information communication tool, exosomes present non-coding RNAs that are involved in breast cancer cell proliferation, migration, invasion, tumour-associated fibroblasts ogenesis, cell cycle, degradation of oncogenes, etc. This paper reviews the relationship between exosomes and the tumour microenvironment and the role of their presenting non-coding RNAs on breast cancer as well as their clinical applications in order to provide new ideas for biological research and therapeutic strategies.

, authors=Xue-li MA^1a, Jun-liang WANG^1a, Juan-xia SUN^1a, Jing-rui WANG^1a, Rui TAO^1a, Chun YU^1b, Tao HAN^{1a, 2}, Yong-mei LAN³, authorsList=Xue-li MA, Jun-liang WANG, Juan-xia SUN, Jing-rui WANG, Rui TAO, Chun YU, Tao HAN, Yong-mei LAN, authorCompany=null, correspAuthors=Tao HAN, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1291339119989351320, articleId=1291339117946725270, tenantId=1146029695717560320, journalId=1246415772164075586, language=CN, title=外泌体与肿瘤微环境的关系及其递呈非编码RNA对乳腺癌的影响, columnId=1246531408819278046, journalTitle=中国临床药理学杂志, columnName=综述, runingTitle=null, highlight=null, articleAbstract=

乳腺癌的发生发展与其微环境的信息传递息息相关。外泌体作为一种新型的信息通讯工具，其递呈非编码RNA参与乳腺癌细胞的增殖、迁移、侵袭，肿瘤相关成纤维细胞生成，细胞周期、致癌基因的降解等过程。本文综述了外泌体与肿瘤微环境的关系及其递呈非编码RNA对乳腺癌的作用以及在临床的应用，以期为乳腺癌的生物学研究和治疗提供新的思路和策略。

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马学莉（1998-），女，硕士研究生，主要从事中药及复方临床应用的相关研究

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马学莉（1998-），女，硕士研究生，主要从事中药及复方临床应用的相关研究

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