Article(id=1292135460130804736, tenantId=1146029695717560320, journalId=1246415772164075586, issueId=1292135402790482407, articleNumber=null, orderNo=null, doi=10.13699/j.cnki.1001-6821.2026.11.023, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1753891200000, receivedDateStr=2025-07-31, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1785998700410, onlineDateStr=2026-08-06, pubDate=1781625600000, pubDateStr=2026-06-17, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1785998700410, onlineIssueDateStr=2026-08-06, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1785998700410, creator=13701087609, updateTime=1785998700410, updator=13701087609, issue=Issue{id=1292135402790482407, tenantId=1146029695717560320, journalId=1246415772164075586, year='2026', volume='42', issue='11', pageStart='1501', pageEnd='1650', issueExtLink='null', onlineDate='null', pubDate='1781625600000', pubDateStr='2026-06-17', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=1, specialIssue=null, createTime=1785998686739, creator='13701087609', updateTime=1786014315540, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1292200954833686587, tenantId=1146029695717560320, journalId=1246415772164075586, issueId=1292135402790482407, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1292200954833686588, tenantId=1146029695717560320, journalId=1246415772164075586, issueId=1292135402790482407, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=1647, endPage=1650, ext={EN=ArticleExt(id=1292135462102126593, articleId=1292135460130804736, tenantId=1146029695717560320, journalId=1246415772164075586, language=EN, title=A brief analysis of the implementation and management of clinical trials of radioactive therapeutic drugs in China, columnId=1291704889697137247, journalTitle=Chinese Journal of Clinical Pharmacology, columnName=Special Column of Clinical Trials Administration, runingTitle=null, highlight=null, articleAbstract=

Radioactive therapeutic drugs have great potential in precise treatment and integrated diagnosis and treatment, especially in the diagnosis and treatment of major diseases such as malignant tumors and central nervous system disorders. Global research on radioactive therapeutic drugs is currently in a period of rapid development. However, the uniqueness of radioactive therapeutic drugs poses challenges to the research, use, and regulation of the drugs. This article explores the special requirements in the implementation process of clinical trials of radioactive therapeutic drugs, such as the qualifications of research institutions, ethical review, drug management, treatment and monitoring of subjects, and multi-disciplinary cooperation. The aim is to provide references for the safe, standardized, and effective implementation and management of radioactive drug clinical trials.

, authors=Yu LIU1a, Ming-ying LU1a, Qian-qian GENG1b, Ai-min YANG1b, Qing-yue LIU1a, Yue WU1a, authorsList=Yu LIU, Ming-ying LU, Qian-qian GENG, Ai-min YANG, Qing-yue LIU, Yue WU, authorCompany=null, correspAuthors=Yue WU, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1292135462920015874, articleId=1292135460130804736, tenantId=1146029695717560320, journalId=1246415772164075586, language=CN, title=浅析我国放射性治疗药物临床试验的实施与管理, columnId=1291704889869103713, journalTitle=中国临床药理学杂志, columnName=临床试验管理专栏, runingTitle=null, highlight=null, articleAbstract=

放射性治疗药物因其在精准治疗、诊疗一体化方面具有巨大潜力,特别是在恶性肿瘤、中枢神经系统疾病等重大疾病的诊治取得了重要进展,全球放射性治疗药物研发正处于快速发展的时期。然而放射性治疗药品的特殊性,使得药品的研发、使用和监管均面临挑战性。本文通过探讨放射性治疗药物临床试验在实施过程中的特殊要求,如研究机构资质、伦理审查、药品管理、受试者治疗和监测、多学科合作等方面的考量,旨在为放射性药物临床试验的安全、规范、有效实施和管理提供参考。

, authors=刘妤1a, 陆明莹1a, 耿倩倩1b, 杨爱民1b, 刘清悦1a, 吴岳1a, authorsList=刘妤, 陆明莹, 耿倩倩, 杨爱民, 刘清悦, 吴岳, authorCompany=null, correspAuthors=吴岳, authorNote=

刘妤(1989-),女,硕士研究生,主要从事医院临床试验管理研究

, correspAuthorsNote=
吴岳,教授,博士生导师 Tel: (029)85323800 E-mail:
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刘妤(1989-),女,硕士研究生,主要从事医院临床试验管理研究

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刘妤(1989-),女,硕士研究生,主要从事医院临床试验管理研究

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浅析我国放射性治疗药物临床试验的实施与管理
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刘妤 1a , 陆明莹 1a , 耿倩倩 1b , 杨爱民 1b , 刘清悦 1a , 吴岳 1a
中国临床药理学杂志 | 临床试验管理专栏 2026,42(11): 1647-1650
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中国临床药理学杂志 |临床试验管理专栏 2026 , 42 (11) : 1647 -1650
浅析我国放射性治疗药物临床试验的实施与管理
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刘妤1a, 陆明莹1a, 耿倩倩1b, 杨爱民1b, 刘清悦1a, 吴岳1a
作者信息
  • 1a.西安交通大学 第一附属医院 科学技术部,陕西 西安 710061
  • 1b.西安交通大学 第一附属医院 核医学科,陕西 西安 710061
通讯作者:
吴岳,教授,博士生导师 Tel: (029)85323800 E-mail:
作者简介:

刘妤(1989-),女,硕士研究生,主要从事医院临床试验管理研究

A brief analysis of the implementation and management of clinical trials of radioactive therapeutic drugs in China
Yu LIU1a, Ming-ying LU1a, Qian-qian GENG1b, Ai-min YANG1b, Qing-yue LIU1a, Yue WU1a
Affiliations
  • 1a.Department of Science and Technology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710061, Shaanxi Province, China
  • 1b.Department of Nuclear Medicine, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710061, Shaanxi Province, China
出版时间: 2026-06-17 doi: 10.13699/j.cnki.1001-6821.2026.11.023
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放射性治疗药物因其在精准治疗、诊疗一体化方面具有巨大潜力,特别是在恶性肿瘤、中枢神经系统疾病等重大疾病的诊治取得了重要进展,全球放射性治疗药物研发正处于快速发展的时期。然而放射性治疗药品的特殊性,使得药品的研发、使用和监管均面临挑战性。本文通过探讨放射性治疗药物临床试验在实施过程中的特殊要求,如研究机构资质、伦理审查、药品管理、受试者治疗和监测、多学科合作等方面的考量,旨在为放射性药物临床试验的安全、规范、有效实施和管理提供参考。

放射性药物  /  临床试验  /  临床试验管理

Radioactive therapeutic drugs have great potential in precise treatment and integrated diagnosis and treatment, especially in the diagnosis and treatment of major diseases such as malignant tumors and central nervous system disorders. Global research on radioactive therapeutic drugs is currently in a period of rapid development. However, the uniqueness of radioactive therapeutic drugs poses challenges to the research, use, and regulation of the drugs. This article explores the special requirements in the implementation process of clinical trials of radioactive therapeutic drugs, such as the qualifications of research institutions, ethical review, drug management, treatment and monitoring of subjects, and multi-disciplinary cooperation. The aim is to provide references for the safe, standardized, and effective implementation and management of radioactive drug clinical trials.

radioactive therapy drugs  /  clinical trials  /  clinical trial management
刘妤, 陆明莹, 耿倩倩, 杨爱民, 刘清悦, 吴岳. 浅析我国放射性治疗药物临床试验的实施与管理. 中国临床药理学杂志, 2026 , 42 (11) : 1647 -1650 . DOI: 10.13699/j.cnki.1001-6821.2026.11.023
Yu LIU, Ming-ying LU, Qian-qian GENG, Ai-min YANG, Qing-yue LIU, Yue WU. A brief analysis of the implementation and management of clinical trials of radioactive therapeutic drugs in China[J]. Chinese Journal of Clinical Pharmacology, 2026 , 42 (11) : 1647 -1650 . DOI: 10.13699/j.cnki.1001-6821.2026.11.023
  • 西安交通大学第一附属医院科研发展基金资助项目(2022RKX-06)
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doi: 10.13699/j.cnki.1001-6821.2026.11.023
  • 接收时间:2025-07-31
  • 首发时间:2026-08-06
  • 出版时间:2026-06-17
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  • 收稿日期:2025-07-31
基金
西安交通大学第一附属医院科研发展基金资助项目(2022RKX-06)
作者信息
    1a.西安交通大学 第一附属医院 科学技术部,陕西 西安 710061
    1b.西安交通大学 第一附属医院 核医学科,陕西 西安 710061

通讯作者:

吴岳,教授,博士生导师 Tel: (029)85323800 E-mail:
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2种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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