Article(id=1292130411057017502, tenantId=1146029695717560320, journalId=1246415772164075586, issueId=1292130366320562708, articleNumber=null, orderNo=null, doi=10.13699/j.cnki.1001-6821.2026.07.019, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1769011200000, receivedDateStr=2026-01-22, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1785997496618, onlineDateStr=2026-08-06, pubDate=1776355200000, pubDateStr=2026-04-17, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1785997496618, onlineIssueDateStr=2026-08-06, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1785997496618, creator=13701087609, updateTime=1785997496618, updator=13701087609, issue=Issue{id=1292130366320562708, tenantId=1146029695717560320, journalId=1246415772164075586, year='2026', volume='42', issue='7', pageStart='901', pageEnd='1050', issueExtLink='null', onlineDate='null', pubDate='1776355200000', pubDateStr='2026-04-17', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1785997485952, creator='13701087609', updateTime=1786014433453, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1292201449350516861, tenantId=1146029695717560320, journalId=1246415772164075586, issueId=1292130366320562708, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1292201449350516862, tenantId=1146029695717560320, journalId=1246415772164075586, issueId=1292130366320562708, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=1019, endPage=1024, ext={EN=ArticleExt(id=1292130411279315615, articleId=1292130411057017502, tenantId=1146029695717560320, journalId=1246415772164075586, language=EN, title=Research progress of nanomedicine in renal ischemia-reperfusion injury, columnId=1246531408630534361, journalTitle=Chinese Journal of Clinical Pharmacology, columnName=Review, runingTitle=null, highlight=null, articleAbstract=

Renal ischemia-reperfusion injury is a common clinical condition, resulting from a sudden reduction in renal blood flow and causing serious adverse consequences. Traditional methods for treating renal ischemia-reperfusion injury are difficult to achieve satisfactory therapeutic effects, and there is an urgent need for effective intervention measures in clinical practice. Nanotechnology is an emerging technical means in recent years and is widely applied in the medical field. Compared with traditional drugs, nanodrugs have advantages such as better biocompatibility and surface area effect, and can achieve precise drug delivery, significantly improving the accumulation efficiency of drugs in tissues. This article focuses on the core mechanism of renal ischemia-reperfusion injury-oxidative/nitrosative stress, summarizes the latest research progress of nanodrugs in treating renal ischemia-reperfusion injury, and aims to provide new research ideas and directions for the treatment of renal ischemia-reperfusion injury.

, authors=Chen-hao FENG, Yun-jia SONG, Cai-yun MAO, Zi-jing ZHAO, Na-na CHENG, Jia-xu CHEN, Ning HAN, Xu-tao SUN, authorsList=Chen-hao FENG, Yun-jia SONG, Cai-yun MAO, Zi-jing ZHAO, Na-na CHENG, Jia-xu CHEN, Ning HAN, Xu-tao SUN, authorCompany=null, correspAuthors=Xu-tao SUN, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1292130413183529632, articleId=1292130411057017502, tenantId=1146029695717560320, journalId=1246415772164075586, language=CN, title=纳米药物在肾缺血再灌注损伤中的研究进展, columnId=1246531408819278046, journalTitle=中国临床药理学杂志, columnName=综述, runingTitle=null, highlight=null, articleAbstract=

肾缺血再灌注损伤是临床常见病症，源于肾脏血流量的骤然减少，并引发较为严重的不良后果。然而，传统方法治疗肾缺血再灌注损伤时往往难以取得理想的疗效，因此临床上亟需有效的干预手段。纳米技术作为近年来新兴的技术手段，已广泛应用于医药领域。相较于传统药物，纳米药物具有更好的生物相容性、比表面效应等优势，并实现药物的精准递送，大幅提升了药物在组织内的蓄积效率。本文聚焦于肾缺血再灌注损伤核心发生机制氧化/亚硝化应激，总结了纳米药物治疗肾缺血再灌注损伤的最新研究进展，旨在为肾缺血再灌注损伤的治疗提供新的研究思路与方向。

, authors=冯晨浩, 宋运佳, 毛彩云, 赵子靖, 程娜娜, 陈佳旭, 韩宁, 孙许涛, authorsList=冯晨浩, 宋运佳, 毛彩云, 赵子靖, 程娜娜, 陈佳旭, 韩宁, 孙许涛, authorCompany=null, correspAuthors=孙许涛, authorNote=, correspAuthorsNote=, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=lTcmjtXKPAzpWi39gAJsyA==, magXml=JtjxCfkvfKeDRammFOESwA==, pdfUrl=null, pdf=ruEuN3XDhBVcBgkU1uwLRg==, pdfFileSize=1594282, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=dBoEJRdZOYBQe1QETotYDA==, mapNumber=null, fund=null)}, authors=[Author(id=1292130413439382181, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1292130411057017502, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1292130413548434087, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1292130411057017502, authorId=1292130413439382181, language=EN, stringName=Chen-hao FENG, firstName=Chen-hao, middleName=null, lastName=FENG, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=College of Basic Medical Sciences, Heilongjiang University of Chinese Medicine, Harbin 150000, Heilongjiang Province, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1292130413623931560, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1292130411057017502, authorId=1292130413439382181, language=CN, stringName=冯晨浩, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=黑龙江中医药大学 基础医学院，黑龙江 哈尔滨 150000, bio={"content":"

冯晨浩（2001-），硕士研究生，主要从事缺血再灌注损伤方面的研究

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冯晨浩（2001-），硕士研究生，主要从事缺血再灌注损伤方面的研究

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