Article(id=1292126492083905277, tenantId=1146029695717560320, journalId=1246415772164075586, issueId=1292126460546929080, articleNumber=null, orderNo=null, doi=10.13699/j.cnki.1001-6821.2026.03.021, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1769443200000, receivedDateStr=2026-01-27, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1785996562262, onlineDateStr=2026-08-06, pubDate=1771257600000, pubDateStr=2026-02-17, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1785996562262, onlineIssueDateStr=2026-08-06, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1785996562262, creator=13701087609, updateTime=1785996562262, updator=13701087609, issue=Issue{id=1292126460546929080, tenantId=1146029695717560320, journalId=1246415772164075586, year='2026', volume='42', issue='3', pageStart='301', pageEnd='450', issueExtLink='null', onlineDate='null', pubDate='1771257600000', pubDateStr='2026-02-17', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1785996554742, creator='13701087609', updateTime=1786014541627, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1292201903060963536, tenantId=1146029695717560320, journalId=1246415772164075586, issueId=1292126460546929080, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1292201903060963537, tenantId=1146029695717560320, journalId=1246415772164075586, issueId=1292126460546929080, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=434, endPage=438, ext={EN=ArticleExt(id=1292126492268454654, articleId=1292126492083905277, tenantId=1146029695717560320, journalId=1246415772164075586, language=EN, title=A brief discussion on the clinical safety and evaluation of mRNA vaccines, columnId=1291339025546211579, journalTitle=Chinese Journal of Clinical Pharmacology, columnName=Drug Evaluation and Administration, runingTitle=null, highlight=null, articleAbstract=

Messenger ribonucleic acid (mRNA) vaccines represent a relatively new vaccine technology and have currently been applied to vaccine development across multiple infectious disease areas. To ensure the safety of participants, the safety evaluation of mRNA vaccines remains a key focus in current vaccine clinical research. This article discusses the safety assessment of preventive mRNA vaccines, drawing on clinical safety data and evaluations from currently marketed vaccines.

, authors=Lin-yu LIU, Shuang LU, authorsList=Lin-yu LIU, Shuang LU, authorCompany=null, correspAuthors=Shuang LU, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1292126492520112895, articleId=1292126492083905277, tenantId=1146029695717560320, journalId=1246415772164075586, language=CN, title=浅谈mRNA疫苗的临床安全性及评价, columnId=1291339025730760957, journalTitle=中国临床药理学杂志, columnName=药物评价与管理, runingTitle=null, highlight=null, articleAbstract=

信使核糖核酸（mRNA）疫苗为较新的疫苗技术路线，目前已应用于多传染病领域疫苗研发。为确保受试者安全，mRNA疫苗的安全性评价仍是目前疫苗临床研发中需关注的重点。本文结合目前已上市的预防性mRNA疫苗的临床安全性及评价，对预防性mRNA疫苗的安全性评价进行探讨。

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刘琳玉（1986-），女，主治医师，主要从事疫苗临床专业审评相关研究及工作

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刘琳玉（1986-），女，主治医师，主要从事疫苗临床专业审评相关研究及工作

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