Article(id=1291706980209546031, tenantId=1146029695717560320, journalId=1246415772164075586, issueId=1291706966187991876, articleNumber=null, orderNo=null, doi=10.13699/j.cnki.1001-6821.2025.24.014, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1763913600000, receivedDateStr=2025-11-24, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1785896542837, onlineDateStr=2026-08-05, pubDate=1766851200000, pubDateStr=2025-12-28, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1785896542837, onlineIssueDateStr=2026-08-05, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1785896542837, creator=13701087609, updateTime=1785896542837, updator=13701087609, issue=Issue{id=1291706966187991876, tenantId=1146029695717560320, journalId=1246415772164075586, year='2025', volume='41', issue='24', pageStart='3451', pageEnd='3600', issueExtLink='null', onlineDate='null', pubDate='1766851200000', pubDateStr='2025-12-28', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1785896539494, creator='13701087609', updateTime=1785998798662, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1292135872292479273, tenantId=1146029695717560320, journalId=1246415772164075586, issueId=1291706966187991876, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1292135872296673578, tenantId=1146029695717560320, journalId=1246415772164075586, issueId=1291706966187991876, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=3536, endPage=3542, ext={EN=ArticleExt(id=1291706980444427056, articleId=1291706980209546031, tenantId=1146029695717560320, journalId=1246415772164075586, language=EN, title=Analysis of the rationality of internet outpatient prescription in children’s specialized hospitals based on the rational drug use system, columnId=1291704944038536012, journalTitle=Chinese Journal of Clinical Pharmacology, columnName=Rational Use of Drugs, runingTitle=null, highlight=null, articleAbstract=
Objective In the context of "internet plus health care", the annual internet outpatient prescriptions of a tertiary children′s hospital (Beijing Children′s Hospital affiliated to Capital Medical University, hereinafter referred to as the hospital) were taken as the objects, and the rationality of prescriptions was analyzed based on the rational drug use system, and the types, causes and drug characteristics of unreasonable treatments were identified to provide data support for the rational drug use management of pediatric Internet outpatient.
Methods All prescriptions from the hospital′s internet outpatient hospital information system (HIS) in 2024 were collected and summarized. Review results were obtained by relying on the Puhua Hecheng Rational Drug Use System, and true positive irrational prescriptions were determined by combining with pharmacists′ manual re-evaluation. Statistical analysis was performed using Excel software.
Results A total of 58 560 internet outpatient prescriptions were included. The rational drug use software reviewed 1 334 machine-screened positive irrational prescriptions, and 438 true-positive irrational prescriptions were confirmed after manual re-evaluation, with an overall irrational rate of 0.75%. Among the 438 prescriptions, 93.61% involved only one irrational drug item, and a total of 559 medication problems were detected. Among these, inappropriate indication accounted for the highest proportion (63.51%), which was identified as the primary factor by Pareto analysis. Among the problems of inappropriate dosage and usage, 80.22% involved two combined issues (primarily single-dose overdose and daily-dose overdose, accounting for 61.54%). Inappropriate administration route was mainly attributed to non-standard labeling of "as needed" (70.00%), primarily involving nebulized drugs and nutritional supplements. The top three medications involved in irrational prescriptions were all nutritional supplements and vitamins, with this category ranking first among medication classifications.
Conclusion The overall rationality of prescriptions in the hospital's pediatric internet-based outpatient service is relatively high. However, inappropriate indications and non-standard dosage and usage remain core issues. Targeted optimization of rational drug use system rules, enhanced pharmaceutical intervention, strengthened physician training, and improved remote consultation processes are needed to enhance medication safety and achieve continuous improvement.
, authors=Zhao-yang DU, Qiang SHI, Zi-yang SONG, Xin-wei CHEN, Jin-jing MA, Xin LIU, Lei ZHANG, Jing-hai WEI, Peng GUO, authorsList=Zhao-yang DU, Qiang SHI, Zi-yang SONG, Xin-wei CHEN, Jin-jing MA, Xin LIU, Lei ZHANG, Jing-hai WEI, Peng GUO, authorCompany=null, correspAuthors=Peng GUO, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1291706980889023281, articleId=1291706980209546031, tenantId=1146029695717560320, journalId=1246415772164075586, language=CN, title=基于合理用药系统的儿童专科医院互联网门诊处方合理性分析, columnId=1291704944210502478, journalTitle=中国临床药理学杂志, columnName=合理用药, runingTitle=null, highlight=null, articleAbstract=
目的 在“互联网+医疗健康”背景下，以某三级儿童专科医院（首都医科大学附属北京儿童医院，以下简称该院）全年度的互联网门诊处方为对象，基于合理用药系统分析处方合理性，明确不合理处方的类型、成因及药品特征，为儿科互联网门诊的合理用药管理提供数据支撑。
方法 收集2024年度该院互联网门诊医院信息系统（HIS）的所有处方，依托普华和诚合理用药系统获取点评结果，经处方审核合药师人工复审判定真阳性不合理处方，用Excel软件进行统计分析。
结果 共纳入互联网门诊处方共计58 560张，经合理用药软件点评得到机筛阳性不合理处方1 334张，经人工复审得真阳性不合理处方438张，整体不合理率为0.75%；438张处方中93.61%仅涉及1种不合理药品条目，共检出559项用药问题，其中适应症不适宜占比最高（63.51%），为帕累托分析界定的主要因素；用法用量不适宜中80.22%涉及2种联合问题（以单次用药超量和单日用药超量为主，61.54%）；给药途径不适宜以“备用”标注不规范（70.00%）为主，主要涉及雾化药物及营养补充剂；不合理处方涉及的前3位药品均为营养补充剂及维生素类，该类别药品占比居药品分类首位。
结论 该院儿童互联网门诊处方整体合理性较好，但适应症不适宜、用法用量不规范仍是核心问题，需针对性优化合理用药系统规则、增加药学干预、强化医师培训及完善远程问诊流程，以提升用药安全和持续改进优化。
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杜朝阳（1991-），女，主管药师，主要从事儿科临床药学研究和工作
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