Article(id=1291707074430398677, tenantId=1146029695717560320, journalId=1246415772164075586, issueId=1291707004800750583, articleNumber=null, orderNo=null, doi=10.13699/j.cnki.1001-6821.2025.22.015, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1754323200000, receivedDateStr=2025-08-05, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1785896565301, onlineDateStr=2026-08-05, pubDate=1764259200000, pubDateStr=2025-11-28, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1785896565301, onlineIssueDateStr=2026-08-05, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1785896565301, creator=13701087609, updateTime=1785896565301, updator=13701087609, issue=Issue{id=1291707004800750583, tenantId=1146029695717560320, journalId=1246415772164075586, year='2025', volume='41', issue='22', pageStart='3151', pageEnd='3300', issueExtLink='null', onlineDate='null', pubDate='1764259200000', pubDateStr='2025-11-28', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1785896548700, creator='13701087609', updateTime=1785896693213, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1291707610999316815, tenantId=1146029695717560320, journalId=1246415772164075586, issueId=1291707004800750583, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1291707610999316816, tenantId=1146029695717560320, journalId=1246415772164075586, issueId=1291707004800750583, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=3248, endPage=3254, ext={EN=ArticleExt(id=1291707074782720214, articleId=1291707074430398677, tenantId=1146029695717560320, journalId=1246415772164075586, language=EN, title=Research progress of traditional Chinese medicine regulating ferroptosis in the treatment of sepsis-induced cardiomyopathy, columnId=1246531408630534361, journalTitle=Chinese Journal of Clinical Pharmacology, columnName=Review, runingTitle=null, highlight=null, articleAbstract=

Sepsis-induced cardiomyopathy is a common cardiovascular complication among septic patients, which significantly increases mortality rates. Ferroptosis is an iron-dependent form of regulated cell death characterized by increased lipid reactive oxygen species (ROS), which causes lipid peroxidation and cell membrane damage. Increasing evidence has highlighted a significant link between ferroptosis and sepsis-induced cardiomyopathy, in which traditional Chinese medicine (TCM) exhibits promising therapeutic potential. This article reviews the mechanism of ferroptosis and current advances in the use of TCM active ingredients and formulated preparations to target ferroptosis in treating sepsis-induced cardiomyopathy, aiming to offer new perspectives for clinical management.

, authors=Ya-yun WANG, Tian-peng HE, Long-fei GUO, authorsList=Ya-yun WANG, Tian-peng HE, Long-fei GUO, authorCompany=null, correspAuthors=Long-fei GUO, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1291707075130847447, articleId=1291707074430398677, tenantId=1146029695717560320, journalId=1246415772164075586, language=CN, title=中药调控铁死亡治疗脓毒症心肌病的研究进展, columnId=1246531408819278046, journalTitle=中国临床药理学杂志, columnName=综述, runingTitle=null, highlight=null, articleAbstract=

脓毒症心肌病是脓毒症患者中常见的心血管并发症，其显著增加脓毒症患者的死亡率。铁死亡是一种新型的铁依赖性调节性细胞死亡方式，以脂质活性氧（ROS）增多为特征，导致脂质过氧化及细胞膜损伤。近年来，研究显示脓毒症心肌病与铁死亡关系密切，中药（TCM）在其治疗中发挥积极作用。本文综述铁死亡的作用机制，中药单体及复方通过铁死亡途径干预脓毒症心肌病的研究现状，以期为脓毒症心肌病的治疗提供新的思路。

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王亚运（1990-），男，主治医师，主要从事重症感染诊治的工作

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王亚运（1990-），男，主治医师，主要从事重症感染诊治的工作

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