Article(id=1291404838982635985, tenantId=1146029695717560320, journalId=1246415772164075586, issueId=1291404681641713991, articleNumber=null, orderNo=null, doi=10.13699/j.cnki.1001-6821.2025.07.025, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1728662400000, receivedDateStr=2024-10-12, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1785824506754, onlineDateStr=2026-08-04, pubDate=1744819200000, pubDateStr=2025-04-17, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1785824506754, onlineIssueDateStr=2026-08-04, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1785824506754, creator=13701087609, updateTime=1785824506754, updator=13701087609, issue=Issue{id=1291404681641713991, tenantId=1146029695717560320, journalId=1246415772164075586, year='2025', volume='41', issue='7', pageStart='901', pageEnd='1050', issueExtLink='null', onlineDate='null', pubDate='1744819200000', pubDateStr='2025-04-17', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1785824469242, creator='13701087609', updateTime=1785824469242, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext=null, issueFiles=null, downloadFileDto=null}, startPage=1038, endPage=1043, ext={EN=ArticleExt(id=1291404839192351186, articleId=1291404838982635985, tenantId=1146029695717560320, journalId=1246415772164075586, language=EN, title=Research status of cardiovascular complications in diabetic nephropathy patients, columnId=1246531408630534361, journalTitle=Chinese Journal of Clinical Pharmacology, columnName=Review, runingTitle=null, highlight=null, articleAbstract=

After the occurrence of complications in diabetes mellitus (DM) patients, the condition will be aggravated, resulting in sustained effects on multiple tissues and organs in the body, thus many complications. Chronic kidney disease (CKD) and cardiovascular disease (CVD) are major complications of type 2 diabetes mellitus (T2DM), increasing the risk of cardiovascular and all-cause death. Current therapeutic agents that delay the progression of CKD and CVD include angiotensin-converting enzyme inhibitors, angiotensin Ⅱ receptor blockers, sodium-glucose cotransporter 2 inhibitors, glucagon-like peptide-1 receptor agonists and salocorticoid receptor antagonists, etc. Although the use of these drugs can delay the progression of macrovascular and microvascular complications in patients with diabetes, T2DM patients with CKD are still at high risk of CVD. This review explores the relationship between CKD and CVD in T2DM patients, in order to provide evidence for clinical treatment.

, authors=Hong-mei MA¹, Zhen-ya WU¹, Li-juan WANG¹, Sheng-nan LIU¹, Fei-ru WANG², Hui-hui TANG¹, Wen YANG², Zi-qiong WANG², Jin-yang WANG³, authorsList=Hong-mei MA, Zhen-ya WU, Li-juan WANG, Sheng-nan LIU, Fei-ru WANG, Hui-hui TANG, Wen YANG, Zi-qiong WANG, Jin-yang WANG, authorCompany=null, correspAuthors=Jin-yang WANG, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1291404839792136659, articleId=1291404838982635985, tenantId=1146029695717560320, journalId=1246415772164075586, language=CN, title=糖尿病肾病患者发生心血管并发症的研究现状, columnId=1246531408819278046, journalTitle=中国临床药理学杂志, columnName=综述, runingTitle=null, highlight=null, articleAbstract=

糖尿病（DM）患者出现并发症后，会加重病情，导致体内多组织器官受到持续性影响，进而出现诸多的并发症。慢性肾疾病（CKD）和心血管疾病（CVD）是2型糖尿病（T2DM）的主要并发症，增加了心血管和全因死亡的风险。目前，延缓CKD进展和CVD发展的治疗药物包括血管紧张素转换酶抑制药、血管紧张素Ⅱ受体阻滞药、钠-葡萄糖共转运蛋白2抑制药、胰高血糖素样肽-1受体激动药、盐皮质激素受体拮抗药等。尽管使用上述药物治疗可以延缓糖尿病患者大血管和微血管并发症的进展，但T2DM合并CKD患者仍存在CVD的高风险。本综述深入探讨T2DM患者CKD与CVD之间的关系，以期为临床治疗提供依据。

, authors=马红梅¹, 武振亚¹, 王丽娟¹, 刘胜男¹, 王飞茹², 汤惠惠¹, 杨文², 王紫琼², 王金羊³, authorsList=马红梅, 武振亚, 王丽娟, 刘胜男, 王飞茹, 汤惠惠, 杨文, 王紫琼, 王金羊, authorCompany=null, correspAuthors=王金羊, authorNote=, correspAuthorsNote=, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=kNx9kXVlJwTjkfYPbPvpvw==, magXml=skXB7ydw38snnGs/ltKMuQ==, pdfUrl=null, pdf=pAvvS3NEBUYTEkNDBnhLZg==, pdfFileSize=1383300, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=Fk+0kzOwihEGqdtg1AziTQ==, mapNumber=null, fund=null)}, authors=[Author(id=1291404842359050718, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404838982635985, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1291404842442936800, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404838982635985, authorId=1291404842359050718, language=EN, stringName=Hong-mei MA, firstName=Hong-mei, middleName=null, lastName=MA, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1.The First Clinical Medical College, Gansu University of Chinese Medicine, Lanzhou 730000, Gansu Province, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1291404842707177953, tenantId=1146029695717560320, journalId=1246415772164075586, articleId=1291404838982635985, authorId=1291404842359050718, language=CN, stringName=马红梅, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1.甘肃中医药大学 第一临床医学院，甘肃 兰州 730000, bio={"content":"

马红梅（1998-），女，硕士研究生，主要从事糖尿病肾病和糖尿病心血管疾病的治疗与机制研究

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马红梅（1998-），女，硕士研究生，主要从事糖尿病肾病和糖尿病心血管疾病的治疗与机制研究

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