Article(id=1291404314665283691, tenantId=1146029695717560320, journalId=1246415772164075586, issueId=1291404284806030089, articleNumber=null, orderNo=null, doi=10.13699/j.cnki.1001-6821.2025.04.028, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1719158400000, receivedDateStr=2024-06-24, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1785824381747, onlineDateStr=2026-08-04, pubDate=1740672000000, pubDateStr=2025-02-28, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1785824381747, onlineIssueDateStr=2026-08-04, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1785824381747, creator=13701087609, updateTime=1785824381747, updator=13701087609, issue=Issue{id=1291404284806030089, tenantId=1146029695717560320, journalId=1246415772164075586, year='2025', volume='41', issue='4', pageStart='451', pageEnd='600', issueExtLink='null', onlineDate='null', pubDate='1740672000000', pubDateStr='2025-02-28', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1785824374629, creator='13701087609', updateTime=1785897184019, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1291709669605663367, tenantId=1146029695717560320, journalId=1246415772164075586, issueId=1291404284806030089, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1291709669605663368, tenantId=1146029695717560320, journalId=1246415772164075586, issueId=1291404284806030089, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=586, endPage=590, ext={EN=ArticleExt(id=1291404316343005292, articleId=1291404314665283691, tenantId=1146029695717560320, journalId=1246415772164075586, language=EN, title=Research status of traditional Chinese medicine regulating PI3K/Akt signaling pathway to intervene in endometriosis, columnId=1246531408630534361, journalTitle=Chinese Journal of Clinical Pharmacology, columnName=Review, runingTitle=null, highlight=null, articleAbstract=

The phosphatidy linositol 3-kinase/protein kinase B (PI3K/Akt) signaling pathway promotes the occurrence and development of endometriosis (EMs) by participating in angiogenesis and cell invasion. In recent years, with the deepening of pharmacological research, traditional Chinese medicine (TCM) has been widely recognized for its advantages of multi-targets, multi-pathways, and fewer adverse drug reactions, and the research on the treatment of EMs by TCM through the modulation of the PI3K/Akt signaling pathway has also achieved certain results. Based on this, this paper analyzes the roles of single Chinese medicine, Chinese medicinal compound and TCM therapeutic methods in regulating the PI3K/Akt signaling pathway in the treatment of EMs, with the aim of providing a theoretical basis for the treatment of EMs by TCM.

, authors=Ya-ru LI¹, Hong QU², Ya-nan ZHANG¹, Cai-feng XU², authorsList=Ya-ru LI, Hong QU, Ya-nan ZHANG, Cai-feng XU, authorCompany=null, correspAuthors=Cai-feng XU, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1291404316749852781, articleId=1291404314665283691, tenantId=1146029695717560320, journalId=1246415772164075586, language=CN, title=中医药调控PI3K/Akt信号通路干预子宫内膜异位症的研究现状, columnId=1246531408819278046, journalTitle=中国临床药理学杂志, columnName=综述, runingTitle=null, highlight=null, articleAbstract=

磷脂酰肌醇-3激酶/蛋白激酶B（PI3K/Akt）信号通路通过参与血管生成、细胞侵袭等促进子宫内膜异位症（EMs）的发生与发展。近年来，随着药理研究的深入，中医药以其多靶点、多途径、少药物不良反应等优势被广泛认可，中医药通过调控PI3K/Akt信号通路治疗EMs的研究也取得了一定的成果。基于此，本文通过分析单味中药、中药复方及中医治疗方法在调节PI3K/Akt信号通路治疗EMs中的作用，以期为中医药治疗EMs提供理论依据。

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李雅茹（1999-），女，硕士研究生，主要从事中医药调控女性神经内分泌的研究

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李雅茹（1999-），女，硕士研究生，主要从事中医药调控女性神经内分泌的研究

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