Article(id=1291339073117999579, tenantId=1146029695717560320, journalId=1246415772164075586, issueId=1291339021272211834, articleNumber=null, orderNo=null, doi=10.13699/j.cnki.1001-6821.2025.02.001, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1729699200000, receivedDateStr=2024-10-24, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1785808826950, onlineDateStr=2026-08-04, pubDate=1737993600000, pubDateStr=2025-01-28, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1785808826950, onlineIssueDateStr=2026-08-04, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1785808826950, creator=13041195026, updateTime=1785808826950, updator=13041195026, issue=Issue{id=1291339021272211834, tenantId=1146029695717560320, journalId=1246415772164075586, year='2025', volume='41', issue='2', pageStart='151', pageEnd='300', issueExtLink='null', onlineDate='null', pubDate='1737993600000', pubDateStr='2025-01-28', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1785808814590, creator='13041195026', updateTime=1785808814590, updator='13041195026', preIssue=null, nextIssue=null, articleTotal=null, ext=null, issueFiles=null, downloadFileDto=null}, startPage=151, endPage=158, ext={EN=ArticleExt(id=1291339073763922396, articleId=1291339073117999579, tenantId=1146029695717560320, journalId=1246415772164075586, language=EN, title=Analysis of application and funded projects of National Natural Science Foundation of China in Clinical Pharmacology from 2015 to 2024, columnId=1246531407326105792, journalTitle=Chinese Journal of Clinical Pharmacology, columnName=Clinical and Basic Bridging Research, runingTitle=null, highlight=null, articleAbstract=
Objective To analyze the application and funded projects in the field of clinical pharmacology supported by the National Natural Science Foundation of China (NSFC) from 2015 to 2024, aiming to provide a reference for the application.
Methods Information on the application and funded projects under the "Clinical Pharmacology (H3511)" code from 2015 to 2024 was collected from the NSFC management information system, including funding year, project name, project category, funding amount, keywords, research directions, etc. A database was established based on this information for statistical analysis.
Results From 2015 to 2024, 2 031 applications were received for general, young scientist, and regional scientist foundation in the clinical pharmacology research field, with 320 projects funded, accumulating a direct funding of 118.48 million yuan. The number and amount of funded projects showed a fluctuating upward trend. The diseases studied in the applications were mainly concentrated in malignant tumors, cardiovascular and cerebrovascular diseases, neuropsychiatric diseases, and metabolic diseases. The research directions of the applications and funded projects were mainly focused on personalized medication, drug adverse reactions and toxicity, and clinical biomarkers, accounting for 67.6% and 70.3% of the total number of application and funded projects, respectively.
Conclusion With the emergence of new methods and technologies, clinical pharmacology has developed rapidly, and basic research in this field has increasingly attracted attention. The NSFC has always emphasized support for this field. However, there are still some issues of the applications, such as the need to strengthen clinical characteristics, uneven distribution of disease types and research directions, and unbalanced development within the discipline, which require increased attention from clinical pharmacology researchers.
, authors=Nan ZHENG
1, 2, Yue LIU
1, 3, Li-wei HAN
1, authorsList=Nan ZHENG, Yue LIU, Li-wei HAN, authorCompany=null, correspAuthors=Li-wei HAN, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1291339074787332573, articleId=1291339073117999579, tenantId=1146029695717560320, journalId=1246415772164075586, language=CN, title=2015—2024年国家自然科学基金临床药理学领域申请与资助项目分析, columnId=1246531407485489349, journalTitle=中国临床药理学杂志, columnName=临床与基础桥接研究, runingTitle=null, highlight=null, articleAbstract=
目的 对2015—2024年国家自然科学基金临床药理学领域申请与资助项目进行分析，旨在为临床药理学项目的申报提供一定的参考。
方法 在国家自然科学基金管理信息系统中收集2015—2024年“临床药理（H3511）”代码下的申请与资助项目信息，包括资助年度、项目名称、项目类别、资助金额、关键词、研究方向等，据此建立数据库并进行统计分析。
结果 2015—2024年临床药理领域接收面上、青年科学基金、地区科学基金项目申请2 031项，资助320项，累计资助直接经费11 848万元，资助项目数量和金额呈波动上升趋势。申请项目所研究病种主要集中在恶性肿瘤、心脑血管疾病、神经精神疾病、代谢性疾病等。申请和获资助项目研究方向主要集中在个体化用药、临床药物不良反应与毒性、临床生物标志物，分别占申请和获资助项目总数的67.6%与70.3%。
结论 随着新理论、新方法和新技术的不断涌现，临床药理学科得到了快速发展，临床药理学领域基础研究日益受到关注，国家自然科学基金一直重视对该领域的支持，但该领域申请项目也存在临床特色有待加强、疾病种类和研究方向冷热不均、学科内发展不均衡等问题，有待临床药理学研究者加强关注。
, authors=郑楠
1, 2, 刘悦
1, 3, 韩立炜
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郑楠（1984-），女，副研究员，主要从事临床药理相关的研究工作
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1.Department of Health Sciences, National Natural Science Foundation of China, Beijing 100085, China
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1.国家自然科学基金委员会 医学科学部，北京 100085
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