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In order to reduce the number of accidents，casualties and enhance the ability to control the level of accident hazards，and to study the general characteristics and hidden patterns of heavy and large safety accidents in China's chemical production industry，this paper used statistical analysis to comprehensively analyze 41 heavy and large accidents that occurred from 2000 to 2023 in terms of time，region，production stage，type of accidents，causes of accidents and other elements. The results show that the number of accidents shows a fluctuating upward trend in 2007-2019，and July and August are the high incidence period of accident every year. The number of heavy chemical accidents in East China accounts for 52.2% of the whole country，of which 12 accidents occurred in Shandong Province，accounting for 57.1% of the total. The highest proportion of accidents occurred in the formal production stage of enterprises，accounting for 53.6% of the total. The main types of accidents is container explosion. The domino effect exists in accidents，with heavy domino accidents and large domino accidents accounting for 14.63% and 39.02% of the total accidents respectively. There are more accidents with domino effect in heavy and large accidents than those without domino effect，accounting for 53.65%，of which the casualties of accidents with large dominoes account for 40.1% of the total accidents and casualties. The most frequent cause of accident statistics is the illegal execution of production，accounting for 49.3% of the total，and the resulting accidents with domino effect account for 66.6% of the accidents. In response to the problems analyzed in the above accidents，this paper proposes some measures to improve the management system from three perspectives: the company，the equipment and the employees.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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