In order to reduce the risks associated with the continuous growth of airport flight area size and flight volume，the safety resilience assessment of airport flight areas was carried out. First，risk factors were identified by analyzing the historical data of airport flight zones. Second，key risk factor weights were quantified，and a SD-based safety resilience assessment model for airport flight zones was constructed to propose safety resilience indicators. Then，the safety resilience of airport flight zones was assessed through simulation analysis，and targeted enhancement strategies were proposed. Finally，a large domestic airport flight area was taken as the research object to assess its safety resilience. The results show that among the personnel factors，the performance of the flight crew has the greatest impact on the level of operational safety resilience. By controlling the flow in the controlled airspace，enhancing safety awareness and increasing management inputs，the operational safety resilience of the flight area is improved by 9.11%. Among the environmental，equipment and management factors，the degree of improvement of the equipment updating mechanism has the greatest impact on the operational safety resilience level. By accelerating the frequency of equipment renewal，improving equipment deficiencies and increasing management inputs，the operational safety resilience of the flight area is increased by 21.49%.