Upper respiratory tract infections (URTI) are common acute infectious diseases, primarily affecting immunocompromised populations, mainly caused by viral or bacterial infections. Typical symptoms include nasal congestion and coughing, which can progress to lower respiratory tract complications such as asthma, bronchitis, and pneumonia, significantly impacting patients’ health and quality of life. Flavonoid glycosides, bioactive compounds widely found in traditional Chinese medicine, exhibit therapeutic effects against URTI through mechanisms including anti-inflammatory action, inhibition of oxidative stress, antiviral activity and immune regulation. This review summarizes recent research progress on the therapeutic mechanisms of flavonoid glycosides for upper respiratory infections, aiming to provide reference for clarifying the mechanism and clinical application of flavonoid glycosides in the treatment of URTI.

upper respiratory tract infection  /  flavonoid glycosides  /  inflammatory response  /  antiviral  /  immunoregulation  /  antibiosis