Chikungunya fever (CHIK) is an acute infectious disease caused by chikungunya virus and transmitted by Aedes mosquitoes. Its main clinical manifestations are fever, joint pain and rash, and some patients may develop into chronic arthritis. At present, there are no specific antiviral drugs. Based on the theory of “wind evil” in traditional Chinese medicine, this paper systematically summarizes the role and mechanism of wind medicine in preventing and treating this disease. CHIK belongs to the category of “damp-heat” and “epidemic disease”, and its core pathogenesis is that wind and evil are mixed with dampness, heat and toxin, which are confined to muscle surface meridians. Its characteristics of “good behavior and variable numbers” are highly consistent with the clinical manifestations of sudden high fever in acute stage and wandering joint pain in chronic stage. Wind drugs [such as Gegen (Puerariae Lobatae Radix), Fangfeng (Saposhnikoviae Radix), Qianghuo (Notopterygii Rhizoma et Radix), Fangji (Stephaniae Tetrandrae Radix), etc.] have the functions of expelling wind, eliminating dampness and dredging collaterals, and run through all stages of treatment of CHIK. Representative prescriptions such as Xuanbi Decoction and Juanbi Decoction can significantly improve clinical symptoms. Modern research shows that its active components play a therapeutic role by directly inhibiting virus replication, regulating immune inflammatory response and other multi-target mechanisms. This study provides a theoretical basis for antivirus of traditional Chinese medicine, and highlights the unique value of wind medicine in preventing and treating new infectious diseases.

wind evil  /  chikungunya fever  /  chikungunya virus  /  wind medicine  /  Puerariae Lobatae Radix  /  Saposhnikoviae Radix  /  Notopterygii Rhizoma et Radix