Traditional Chinese medicine (TCM) oral liquid is an oral liquid preparation made from Chinese medicinal materials through processes such as extraction, concentration and purification, and it is one of the commonly used liquid preparations. It has the advantages of easy absorption, rapid action and convenient administration, and is widely used in clinical practice. However, TCM oral liquid has a complex composition. During production and storage, it is easily affected by factors such as temperature and light, and undergoes oxidation, degradation, complexation and other reactions, resulting in unstable phenomena such as sedimentation, turbidity, flocculation and stratification. These phenomena have adverse effects on product quality and medication safety. How to regulate the stability of TCM oral liquid through environmental control, clarification process optimization, additive addition and application of advanced formulation technologies is a key issue. Based on this, this paper aims to deeply analyze the factors affecting the stability of TCM oral liquid and the transformation mechanism of its active ingredients on the basis of the active ingredients of TCM oral liquid, and then summarize the control strategies, with the aim of providing theoretical references for research and development and production of TCM oral liquid.

traditional Chinese medicine oral liquid  /  stability  /  influencing factors  /  transformation mechanisms  /  control strategies