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Solid dispersion-based traditional Chinese medicine droplet pills: Pharmaceutical properties, process mechanisms, and smart manufacturing development
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Chinese Traditional and Herbal Drugs | 2026, 57(5) : 1982 - 1994
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Chinese Traditional and Herbal Drugs | 2026, 57(5): 1982-1994
Solid dispersion-based traditional Chinese medicine droplet pills: Pharmaceutical properties, process mechanisms, and smart manufacturing development
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QIAO Chun, HU Jinru, ZHANG Xiaoyu, GONG Zihua, WANG Kexin, HUANG Chenyu, DU Ruofei
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doi: 10.7501/j.issn.0253-2670.2026.05.033
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Traditional Chinese medicine (TCM) dripping pills represent a modern dosage form founded on solid dispersion systems. Characterized by rapid dissolution, enhanced bioavailability, precise dosing, and convenient administration, they exhibit considerable potential in improving the release and absorption of multi-component TCM formulations. This review provides a comprehensive overview of the pharmaceutic characteristics of dripping pills, processing mechanisms, and recent advances in their intelligent manufacturingand and clinical applications. Particular attention is given to the physical states, as well as to the formulation characteristics underlying their rapid-release and solubilization behaviors that enhance oral absorption efficiency. Furthermore, by integrating intelligent manufacturing technology , this article discusses the engineering challenges and developmental strategies associated with process optimization and quality control. Overall, this review aims to offer theoretical insights and technical references for the systematic investigation, industrial upgrading, and clinical translation of TCM dripping pills.
traditional Chinese medicine dripping pills  /  solid dispersion  /  pharmaceutic characteristic  /  intelligent manufacturing  /  process analytical technology
QIAO Chun, HU Jinru, ZHANG Xiaoyu, GONG Zihua, WANG Kexin, HUANG Chenyu, DU Ruofei. Solid dispersion-based traditional Chinese medicine droplet pills: Pharmaceutical properties, process mechanisms, and smart manufacturing development[J]. Chinese Traditional and Herbal Drugs, 2026 , 57 (5) : 1982 -1994 . DOI: 10.7501/j.issn.0253-2670.2026.05.033
Year 2026 volume 57 Issue 5
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doi: 10.7501/j.issn.0253-2670.2026.05.033
  • Receive Date:2025-10-11
  • Online Date:2026-09-09
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  • Received:2025-10-11
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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