Chinese Traditional and Herbal Drugs
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2026, 57(5): 1982-1994
Solid dispersion-based traditional Chinese medicine droplet pills: Pharmaceutical properties, process mechanisms, and smart manufacturing development
Full
QIAO Chun, HU Jinru, ZHANG Xiaoyu, GONG Zihua, WANG Kexin, HUANG Chenyu, DU Ruofei
Affiliations
doi: 10.7501/j.issn.0253-2670.2026.05.033
Outline
Traditional Chinese medicine (TCM) dripping pills represent a modern dosage form founded on solid dispersion systems. Characterized by rapid dissolution, enhanced bioavailability, precise dosing, and convenient administration, they exhibit considerable potential in improving the release and absorption of multi-component TCM formulations. This review provides a comprehensive overview of the pharmaceutic characteristics of dripping pills, processing mechanisms, and recent advances in their intelligent manufacturingand and clinical applications. Particular attention is given to the physical states, as well as to the formulation characteristics underlying their rapid-release and solubilization behaviors that enhance oral absorption efficiency. Furthermore, by integrating intelligent manufacturing technology , this article discusses the engineering challenges and developmental strategies associated with process optimization and quality control. Overall, this review aims to offer theoretical insights and technical references for the systematic investigation, industrial upgrading, and clinical translation of TCM dripping pills.
traditional Chinese medicine dripping pills
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solid dispersion
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pharmaceutic characteristic
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intelligent manufacturing
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process analytical technology
QIAO Chun, HU Jinru, ZHANG Xiaoyu, GONG Zihua, WANG Kexin, HUANG Chenyu, DU Ruofei.
Solid dispersion-based traditional Chinese medicine droplet pills: Pharmaceutical properties, process mechanisms, and smart manufacturing development[J].
Chinese Traditional and Herbal Drugs,
2026
, 57
(5)
: 1982
-1994
.
DOI: 10.7501/j.issn.0253-2670.2026.05.033
Year 2026 volume 57 Issue 5
PDF
34
11
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Article Info
doi: 10.7501/j.issn.0253-2670.2026.05.033
- Receive Date:2025-10-11
- Online Date:2026-09-09