Objective To comprehensively analyze the research trends and focuses of Gouteng (Uncariae Ramulus Cum Uncis) from bibliometric and global patent perspectives, providing forward-looking references for its future clinical application and in-depth research. Methods Literature was retrieved from four databases: China National Knowledge Infrastructure (CNKI), Wanfang, VIP, and Web of Science (WOS) with Uncariae Ramulus Cum Uncis as the keyword. Retrieved publications were imported into NoteExpress for deduplication and screening. Software including Excel, Origin, CiteSpace, and VOSviewer were used to visually analyze the current research status and development trends of Uncariae Ramulus Cum Uncis in domestic and international publications, covering publication trends, national distribution, publication institutions, journal of publication, authors, and keywords. The Incopat patent database was searched to analyze global patent applications related to Uncariae Ramulus Cum Uncis, including trends in patent applications, geographical distribution, applicants, and technology fields. Results A total of 1 713 Chinese publications and 594 English publications met the inclusion criteria. China was the primary contributor to publications, with international attention increasing gradually in recent years. Core research teams have emerged in this field, but collaboration among institutions requires strengthening. In recent years, there has been an overlap in the research hotspots of Chinese and English literature in the field of Uncariae Ramulus Cum Uncis, both focusing on the pharmacological components and action mechanisms of Uncariae Ramulus Cum Uncis. Chinese studies specifically emphasize Tianma Gouteng Decoction and its use in hypertension treatment, identifying bioactive compounds and elucidating regulatory mechanisms. English publications focus on phytochemistry, anti-inflammation, antioxidation, and the potential efficacy in neurological diseases. Based on a search of the Incopat patent database, 8 048 patents were initially screened. After merging patent families, 6 251 patents were retained, among which 5 461 were domestic patents, accounting for 87.36% and occupying a dominant position. Conclusion Research in the field of Uncariae Ramulus Cum Uncis shows a trend of continuous expansion and deepening. Overall, it is shifting from traditional Chinese medicine practice to a development path featuring multi-disciplinary collaborative innovation and in-depth analysis of molecular-level mechanisms. Although China dominates international patent applications related to Uncariae Ramulus Cum Uncis, there are key drawbacks: A large number of patents have expired, the degree of transformation and implementation is limited, and market expansion is weak.

Uncariae Ramulus Cum Uncis  /  bibliometrics  /  visual analysis  /  patent analysis  /  CiteSpace  /  VOSviewer