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Progress of Blast-Induced Traumatic Brain Injury and Protection
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Jing XIE1, 2, Zhixue QU3, Zhihua CAI3
Journal of Medical Biomechanics | 2025, 40(5) : 1101 - 1113
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Journal of Medical Biomechanics | 2025, 40(5): 1101-1113
• Expert Forum •
Progress of Blast-Induced Traumatic Brain Injury and Protection
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Jing XIE1, 2, Zhixue QU3, Zhihua CAI3
Affiliations
  • 1.Key Laboratory of Explosion Science and Technology, Beijing 100081, China
  • 2.Tangshan Research Institute, Beijing Institute of Technology, Tangshan 063000, Hebei, China
  • 3.Sanya Institute of Hunan University of Science and Technology, Sanya 572024, Hainan, China
Published: 2025-10-01 doi: 10.16156/j.1004-7220.2025.05.003
Outline
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Traumatic brain injury caused by blast shock waves represents a significant type of injury in modern warfare and civilian explosion accidents. Its high incidence and complexity have attracted a widespread attention, and the injury mechanism and cranial brain protection have become current research hotspots. This review first analyzes the dynamic load characteristics of blast shock waves and introduces the development and verification of cranial brain constitutive and finite element models to explore the mechanical responses of the cranial brain at tissue and cellular levels under blast waves and bullet impacts. Subsequently, the current state of research on injury mechanisms at tissue and cellular levels and cranial brain protection, is systematically summarized based on domestic and international studies. Finally, the current research challenges and future development directions are outlined, and the importance of interdisciplinary cooperation and innovation to promote the research and application transformation of blast-induced traumatic brain injury is emphasized. The findings provide a valuable reference for enhancing the comprehension of injury mechanism and fostering multi-disciplinary integration and protective helmet development.

blast wave  /  traumatic brain injury  /  craniocerebral mechanical response  /  injury mechanism  /  brain protection
Jing XIE, Zhixue QU, Zhihua CAI. Progress of Blast-Induced Traumatic Brain Injury and Protection[J]. Journal of Medical Biomechanics, 2025 , 40 (5) : 1101 -1113 . DOI: 10.16156/j.1004-7220.2025.05.003
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Year 2025 volume 40 Issue 5
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Article Info
doi: 10.16156/j.1004-7220.2025.05.003
  • Receive Date：2025-03-25
  • Online Date：2026-03-27
  • Published：2025-10-01
Article Data
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History
  • Received：2025-03-25
  • Revised：2025-04-22
Funding
Affiliations
    1.Key Laboratory of Explosion Science and Technology, Beijing 100081, China
    2.Tangshan Research Institute, Beijing Institute of Technology, Tangshan 063000, Hebei, China
    3.Sanya Institute of Hunan University of Science and Technology, Sanya 572024, Hainan, China
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小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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