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Influence of D152 Resin Prewashing Process on the Quality of Spectinomycin
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Cheng WANG, Haichao LI
Uranium Mining and Metallurgy | 2024, 43(3) : 68 - 73
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Uranium Mining and Metallurgy | 2024, 43(3): 68-73
MINING AND HYDROMETALLURGY
Influence of D152 Resin Prewashing Process on the Quality of Spectinomycin
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Cheng WANG, Haichao LI
Affiliations
  • Hebei Shengxue Dacheng Pharmaceutical Co., Ltd., Shijiazhuang 051430, China
Published: 2024-08-20 doi: 10.13426/j.cnki.yky.2024.03.07
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Spectinomycin is an alkaline water-soluble aminoglycoside antibiotic, produced by the fermentation of actinospectacin. The prewashing process of D152 resin with EDTA-2Na was studied, by selecting the proper concentration, pH and flow rate of the prewashing solution, the extraction of high purity macromycin hydrochloride was realized, and the recovery process of EDTA-2Na was determined. The optimal prewashing parameters were obtained: the concentration of EDTA-2Na solution is 0.015 mol/L, the pH of prewashing solution is 7.5~8.0, and the flow rate is 1.0~2.0 BV/h. The prewashing process is simple, low cost and high recovery, which ensures the adsorption yield of D152 resin and realizes the green extraction.

spectinomycin  /  D152 resin  /  prewashing process  /  EDTA-2Na
Cheng WANG, Haichao LI. Influence of D152 Resin Prewashing Process on the Quality of Spectinomycin[J]. Uranium Mining and Metallurgy, 2024 , 43 (3) : 68 -73 . DOI: 10.13426/j.cnki.yky.2024.03.07
Year 2024 volume 43 Issue 3
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doi: 10.13426/j.cnki.yky.2024.03.07
  • Receive Date:2024-03-30
  • Online Date:2025-07-04
  • Published:2024-08-20
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  • Received:2024-03-30
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    Hebei Shengxue Dacheng Pharmaceutical Co., Ltd., Shijiazhuang 051430, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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