In order to promote the informationization construction of mining enterprises and enhance the safety informationization management capabilities, we explore the application of Python programming language and PyCharm editor to establish a basic database and big data analysis model for safety inspections in a certain mining enterprise. We construct a multi-dimensional analysis and evaluation system for historical safety inspection issues, new safety inspection issues, and other data, including time, space, problem categories, and causes. We explore the laws and development trends of intrinsic safety and safety inspection problems, and take targeted solutions accurately. The establishment of databases and analysis model can also be used for comprehensive evaluation of security inspection issues, visually displaying important information such as the time, place, category, and cause of the problem, providing objective data support for timely detection of repetitive problems and hidden danger investigation, avoiding the long-term existence of security problems that cannot be eradicated, and effectively reducing security risks. At present, the security big data model is mainly applied in security inspection work, and there is still room for exploration in the fields of security management system construction, "dual control" system operation, security education and training, accident prediction and warning in the future.