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Function and Mechanism of Ferroptosis in Regulating Follicular Development in Livestock and Poultry
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Runxiao LUO1, 2, Li LI1, 2, Hongping ZHANG1, 2, Siyuan ZHAN1, 2
Acta Veterinaria et Zootechnica Sinica | 2026, 57(3) : 1187 - 1194
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Acta Veterinaria et Zootechnica Sinica | 2026, 57(3): 1187-1194
• REVIEW •
Function and Mechanism of Ferroptosis in Regulating Follicular Development in Livestock and Poultry
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Runxiao LUO1, 2, Li LI1, 2, Hongping ZHANG1, 2, Siyuan ZHAN1, 2
Affiliations
  • 1.College of Animal Science and Technology,Sichuan Agricultural University,Chengdu 611130,China
  • 2.Farm Animal Germplasm Resources and Biotech Breeding Key Laboratory of Sichuan Province,Chengdu 611130,China
Published: 2026-03-23 doi: 10.11843/j.issn.0366-6964.2026.03.002
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Ovarian folliculogenesis is fundamental to the reproductive activity of female mammals, encompassing the formation of primordial follicles, follicular recruitment, dominant follicle selection, ovulation of mature follicles, and the follicular atresia process that persists throughout development. Ferroptosis, a novel form of regulated cell death, plays a critical role in follicular development, particularly during atresia. This review systematically explores the molecular mechanisms of ferroptosis, emphasizing its impact on follicular atresia, primordial follicle activation, and oocyte maturation, as well as the regulatory effects of antioxidants on ferroptosis. The aim is to provide a theoretical reference for further research in this domain.

ferroptosis  /  follicular development  /  granulosa cells  /  regulation mechanism
罗润箫, 李利, 张红平, 占思远. 铁死亡在畜禽卵泡发育调控中的作用及机制. 畜牧兽医学报, 2026 , 57 (3) : 1187 -1194 . DOI: 10.11843/j.issn.0366-6964.2026.03.002
Runxiao LUO, Li LI, Hongping ZHANG, Siyuan ZHAN. Function and Mechanism of Ferroptosis in Regulating Follicular Development in Livestock and Poultry[J]. Acta Veterinaria et Zootechnica Sinica, 2026 , 57 (3) : 1187 -1194 . DOI: 10.11843/j.issn.0366-6964.2026.03.002
Year 2026 volume 57 Issue 3
190
87
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doi: 10.11843/j.issn.0366-6964.2026.03.002
  • Receive Date:2025-07-23
  • Online Date:2026-09-16
  • Published:2026-03-23
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  • Received:2025-07-23
Funding
Affiliations
    1.College of Animal Science and Technology,Sichuan Agricultural University,Chengdu 611130,China
    2.Farm Animal Germplasm Resources and Biotech Breeding Key Laboratory of Sichuan Province,Chengdu 611130,China

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ZHAN Siyuan, E-mail:
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表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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