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Effects of Using Hydrolyzed Wheat Gluten in Artificial Milks on the Growth Performance, Nutrient Metabolism, Immune Function and Antioxidant Capacity of Piglets
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Feiran ZHANG1, Wei DENG2, Fengyu XIANG1, Bing HUANG1, Zhihang LI1, Xiangqi FAN1, Dayan TAN1, Xiangbing MAO1
Acta Veterinaria et Zootechnica Sinica | 2026, 57(2) : 839 - 847
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Acta Veterinaria et Zootechnica Sinica | 2026, 57(2): 839-847
• ANIMAL NUTRITION AND FEEDS •
Effects of Using Hydrolyzed Wheat Gluten in Artificial Milks on the Growth Performance, Nutrient Metabolism, Immune Function and Antioxidant Capacity of Piglets
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Feiran ZHANG1, Wei DENG2, Fengyu XIANG1, Bing HUANG1, Zhihang LI1, Xiangqi FAN1, Dayan TAN1, Xiangbing MAO1
Affiliations
  • 1.Key Laboratory of Animal Disease-Resistant Nutrition of Sichuan Province,Key Laboratory of Animal Disease-Resistant Nutrition and Feed of Ministry of Agriculture and Rural Affairs,Key Laboratory of Animal Disease-Resistance Nutrition of Ministry of Education,Animal Nutrition Institute,Sichuan Agricultural University,Chengdu 611130,China
  • 2.College of Animal Science and Technology,Sichuan Agricultural University,Chengdu 611130,China
Published: 2026-02-23 doi: 10.11843/j.issn.0366-6964.2026.02.023
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In this experiment, the piglets weaned at 7 days of age were used, and the aim was to determine the effect which hydrolyzed wheat gluten (HWG) replacing different doses of whey protein concentrate (WPC) in artificial milks on growth performance, nutrient metabolism, immune function and antioxidant capacity of piglets. Forty-five healthy crossbred (Duroc×Landrace×Yorkshire) piglets at 7 days of age were randomly allotted into four treatments, including control group (n=15), 33%HWG group (n=10), 66%HWG group (n=10), and 100%HWG group (n=10), which were fed the artificial milks that HWG replaced 0%, 33%, 66% and 100% WPC for 13 days, respectively. The results showed that HWG replacing WPC in artificial milks could affect growth performance, nitrogen metabolism, lipid metabolism, kidney function, immune function and antioxidant capacity in piglets. Compared with the piglets of control group, HWG replacing 66% and 100% WPC significantly reduced average daily feed intake and average daily gain (P<0.05), significantly enhanced feed to gain ratio and diarrhea index (P<0.05), significantly decreased serum creatinine (P<0.05), and significantly increased serum malondialdehyde concentrations (P<0.05) in piglets. In addition, serum immunoglobulin A and M levels were significantly reduced (P<0.05) when 66% of WPC was replaced by HWG, and serum high density lipoprotein cholesterol levels were significantly increased (P<0.05) when 100% of WPC was replaced by HWG. Compared with the piglets of control group, serum urea and high density lipoprotein cholesterol levels were significantly higher in the piglets fed the artificial milk that HWG replaced 33% WPC (P<0.05). In summary, HWG replacing different doses of WPC in artificial milks might be not conducive to growth performance, nutrient metabolism, immune function and antioxidant capacity in the early-weaned piglets, but when HWG replacing 33% WPC in artificial milks had not significantly negative effect on piglets.

hydrolyzed wheat gluten  /  piglets  /  growth performance  /  metabolism  /  immune function  /  antioxidant capacity
张斐然, 邓为, 向丰禺, 黄冰, 李智行, 范祥奇, 谭大雁, 毛湘冰. 人工乳用小麦水解蛋白对仔猪生长性能、代谢、免疫和抗氧化的影响. 畜牧兽医学报, 2026 , 57 (2) : 839 -847 . DOI: 10.11843/j.issn.0366-6964.2026.02.023
Feiran ZHANG, Wei DENG, Fengyu XIANG, Bing HUANG, Zhihang LI, Xiangqi FAN, Dayan TAN, Xiangbing MAO. Effects of Using Hydrolyzed Wheat Gluten in Artificial Milks on the Growth Performance, Nutrient Metabolism, Immune Function and Antioxidant Capacity of Piglets[J]. Acta Veterinaria et Zootechnica Sinica, 2026 , 57 (2) : 839 -847 . DOI: 10.11843/j.issn.0366-6964.2026.02.023
Year 2026 volume 57 Issue 2
138
60
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Article Info
doi: 10.11843/j.issn.0366-6964.2026.02.023
  • Receive Date:2025-02-06
  • Online Date:2026-09-16
  • Published:2026-02-23
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  • Received:2025-02-06
Funding
Affiliations
    1.Key Laboratory of Animal Disease-Resistant Nutrition of Sichuan Province,Key Laboratory of Animal Disease-Resistant Nutrition and Feed of Ministry of Agriculture and Rural Affairs,Key Laboratory of Animal Disease-Resistance Nutrition of Ministry of Education,Animal Nutrition Institute,Sichuan Agricultural University,Chengdu 611130,China
    2.College of Animal Science and Technology,Sichuan Agricultural University,Chengdu 611130,China

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MAO Xiangbing, E-mail:
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表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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