This study aimed to systematically evaluate the effects of compound Chinese herbal medicine on growth performance and intestinal flora of chickens. Based on the PRISMA guidelines， this study conducted a Meta-analysis of 21 Chinese literatures （including randomized controlled trials of chickens） published in CNKI， VIP， Wanfang， PubMed and Web of Science databases from the establishment of the database to September 2025. The RevMan 5.4 software was used to calculate the weighted average and 95% confidence interval by random effect model， and to evaluate the heterogeneity and publication bias. The results showed that compound Chinese herbal medicine could significantly increase ADFI （MD=2.42 g·d^-1， 95%CI［1.99， 2.85］） （P<0.01）， ADG （MD=3.23 g·d^-1， 95%CI［2.48， 3.98］） （P<0.01）， and VH/CD （MD=0.87， 95%CI［0.40， 1.35］） （P<0.01） compared with the blank group. Significantly reduced F/G （MD=-0.19， 95%CI［-0.27， -0.11］） （P<0.01） and the number of E.coli （MD=-1.48， 95%CI［-1.87， -1.09］） （P<0.01）， but there was no significant difference between the Chinese herbal medicine group and the blank group in improving Shannon index， Chao1 index， Simpson index and the number of lactic acid bacteria （P>0.05）. Compared with the antibiotic group， there was no significant difference in ADFI， ADG and F/G （P>0.05）. In this study， the effects of compound Chinese herbal medicine on production performance and intestinal health of chickens were evaluated by Meta-analysis system. The results showed that the compound Chinese herbal medicine had a significant effect on ADFI and ADG of broiler and broiler-egg dual-purpose chickens， and the effect was prominent in the brooding period and the growing period. At the same time， it could significantly reduce the F/G of broilers， but had no significant effect on the related indexes of laying hens. Compound Chinese herbal medicine could selectively inhibit the proliferation of Escherichia coli and significantly increase the ratio of intestinal villus height to crypt depth （VH/CD）， but had no significant effect on the diversity index of flora and the number of lactic acid bacteria. The results of this study provide a systematic reference for the application of compound Chinese herbal medicine in chicken production， which is of great significance for the application and in-depth study of Chinese herbal medicine in chicken breeding.