Full
Outline
Zinc uptake regulator (Zur) is a transcriptional regulator of the ferric uptake regulator (FUR) superfamily, which exists in the form of dimers or multimers in most bacteria. Zur contains a conserved DNA-binding domain and Zn2+-binding domain, the latter is essential for Zur to recognize and bind Zn2+. Zn2+ acting as a cofactor can change the conformation of Zur and affecting its DNA binding ability to regulate the expression of zinc transporter-related genes to maintain zinc homeostasis in bacteria. Increasing studies have shown that Zur can be involved in a wide range of metabolic pathways directly or indirectly. By regulating the expression of key genes involved in metabolic pathways, Zur helps bacteria to respond effectively to the external environmental changes, and it is an important component for the bacterial metabolic regulatory network. This article reviews the research progress of Zur in molecular structure, Zn2+ response regulation, regulation of bacterial secondary metabolism, toxicity production and stress response to help researchers gain a more comprehensive understanding and in-depth exploration of the potential functions of Zur in the complex process of bacterial metabolism regulation.
68
16
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
关闭全屏
No. 86 Xueyuan South Road, Haidian District, Beijing
010-62662699(Operation and Technical Support)
qkjq@cast.org.cn
Copyright © 2025 China Association for Science and Technology. All rights reserved. For all open access content, the relevant licensing terms apply.
Sponsored by the Office of the Leading Group for Cybersecurity and Informatization of CAST, and supported by Science and Technology Review Publishing House
