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Research progress in visualization reporter systems for influenza virus
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Jiaqi XIONG1, 3, Wenguang YANG2, Yuehong CHEN3, Biao LI4, Ye FENG3, Tao JIANG1, 3, 4
Acta Microbiologica Sinica | 2026, 66(8) : 3732 - 3744
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Acta Microbiologica Sinica | 2026, 66(8): 3732-3744
• Review •
Research progress in visualization reporter systems for influenza virus
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Jiaqi XIONG1, 3, Wenguang YANG2, Yuehong CHEN3, Biao LI4, Ye FENG3, Tao JIANG1, 3, 4
Affiliations
  • 1.School of Public Health, Mudanjiang Medical University, Mudanjiang, Heilongjiang, China
  • 2.The Second Hospital of the Navy, Southern Theater Command of PLA, Sanya, Hainan, China
  • 3.State Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing, China
  • 4.School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China
Published: 2026-08-04 doi: 10.13343/j.cnki.wsxb.20260130
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The continuous evolution and drug-resistant mutations of influenza virus have placed higher demands on the study of its pathogenic mechanism, as well as the development of antiviral drugs and vaccines. As a key tool for real-time monitoring of viral infection, replication and transmission, viral visualization reporter systems have evolved into various strategies, including high-resolution microscopic imaging, exogenous nanomaterial labeling, recombinant reporter viruses, and virus infection-inducible reporter systems. This manuscript systematically reviewed the research progress of influenza virus visualization technologies, elaborated the principles, core breakthroughs, and application scenarios of each technique, analyzed the common limitations and specific problems existing in the current technical system, and prospected its development direction combined with cutting-edge research, providing a reference for technical selection and innovative applications in influenza virus visualization research.

influenza virus  /  viral tracking  /  high-resolution microscopy technology  /  nanomaterial labeling  /  recombinant reporter virus  /  reporter gene
Jiaqi XIONG, Wenguang YANG, Yuehong CHEN, Biao LI, Ye FENG, Tao JIANG. Research progress in visualization reporter systems for influenza virus[J]. Acta Microbiologica Sinica, 2026 , 66 (8) : 3732 -3744 . DOI: 10.13343/j.cnki.wsxb.20260130
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Article Info
doi: 10.13343/j.cnki.wsxb.20260130
  • Receive Date：2026-02-12
  • Online Date：2026-08-21
  • Published：2026-08-04
Article Data
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History
  • Received：2026-02-12
  • Accepted：2026-03-28
Affiliations
    1.School of Public Health, Mudanjiang Medical University, Mudanjiang, Heilongjiang, China
    2.The Second Hospital of the Navy, Southern Theater Command of PLA, Sanya, Hainan, China
    3.State Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing, China
    4.School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China

Corresponding:

E-mail: JIANG Tao, ;
FENG Ye,
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小菇属 Mycena 11 5.26
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栓菌属 Trametes 5 2.39
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