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Engineered microorganisms, as the core driving force of biomanufacturing and the development of the new bio-economy, demonstrate increasingly prominent strategic values. The newly built Engineered Microorganisms and Genetic Tools Collection Center of China (EMTCC) supported by the Ministry of Education aims to break through the limitations of “microbial culture collection centers” and provide a comprehensive resource innovation service platform supported by information technology and integrating resource acquisition, intelligent creation, data analysis, and open sharing functions. This platform intends to meet the needs of basic research, technology development, and industrial applications. This article elaborates on the building framework of EMTCC, which takes large-scale resource preservation as the basis, intelligent mining and analysis as the core, and digital storage and computing sharing as the link. By carrying out large-scale acquisition and standardized preservation of natural and engineered microorganisms and plasmids and integrating cutting-edge technologies such as high-throughput automation, multi-omics, single-cell analysis, artificial intelligence prediction models, and digital twins, the EMTCC achieves a complete process of “acquisition & preservation, analysis & identification, and data sharing”. On the basis of drawing on the standardization and quality control systems of internationally renowned institutions such as American Type Culture Collection (ATCC), a resource repository model integrating living “organisms, information, and intelligence” will be developed. This innovative practice is expected to provide strong resource guarantee and technical support for research innovation and industrial upgrading in the fields of synthetic biology, metabolic engineering, biomedicine, and environmental remediation.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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