Home Journals Articles Updates About
CN
image
收藏切换
Research progress in genetic diversity and evolutionary mechanism of hepatitis E viruses
收藏切换
PDF
Yongquan XU1, 2, Junshan GAO2, Qingping WU2, Jumei ZHANG2, *, Liang XUE2, *
Acta Microbiologica Sinica | 2024, 64(5) : 1392 - 1401
Less
收藏切换
Acta Microbiologica Sinica | 2024, 64(5): 1392-1401
• Reviews •
Research progress in genetic diversity and evolutionary mechanism of hepatitis E viruses
Full
Yongquan XU1, 2, Junshan GAO2, Qingping WU2, Jumei ZHANG2, *, Liang XUE2, *
Affiliations
  • 1 College of Food Science, South China Agricultural University, Guangzhou 510642, Guangdong, China
  • 2 National Health Commission Science and Technology Innovation Platform for Nutrition and Safety of Microbial Food, Guangdong Provincial Key Laboratory of Microbial Safety and Health, State Key Laboratory of Applied Microbiology Southern China, Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou 510070, Guangdong, China
Published: 2024-05-04 doi: 10.13343/j.cnki.wsxb.20230689
Outline
收藏切换

Hepatitis E virus (HEV) is a major zoonotic pathogen that causes acute viral hepatitis worldwide. HEV has high genetic diversity, and the incidence of various genotypes or subtypes is strongly correlated with host species, geographic location, and prevention and control methods. HEV strains HEV-3, comprising 3a–3i subtypes, were present in Europe and America, whereas HEV-3 and HEV-4 were prevalent in Asia. The epidemic strains in China have evolved from HEV-1 to HEV-4. Recent studies have shown that gene recombination, amino acid mutations, and synonymous codon usage patterns are part of the mechanisms underlying HEV evolution. In particular, amino acid mutations are the main driving force for the continued prevalence of the virus. This paper reviews the classification, global epidemic characteristics, and evolutionary mechanism of HEV, aiming to provide a reference for the prevention and control of hepatitis E and vaccine development.

hepatitis E virus  /  genetic diversity  /  evolution
Yongquan XU, Junshan GAO, Qingping WU, Jumei ZHANG, Liang XUE. Research progress in genetic diversity and evolutionary mechanism of hepatitis E viruses[J]. Acta Microbiologica Sinica, 2024 , 64 (5) : 1392 -1401 . DOI: 10.13343/j.cnki.wsxb.20230689
Funding
Less
  • National Key Research and Development Program of China(2022YFF1103100)
  • National Natural Science Foundation of China(32272436)
  • Key Research and Development Program of Guangdong Province(2022B1111040002)
Appendix
Less
Year 2024 volume 64 Issue 5
PDF
70
27
Cite this Article
BibTeX
Article Info
doi: 10.13343/j.cnki.wsxb.20230689
  • Receive Date：2023-11-09
  • Online Date：2026-03-19
  • Published：2024-05-04
Article Data
Affiliations
History
  • Received：2023-11-09
  • Accepted：2024-01-26
Funding
National Key Research and Development Program of China(2022YFF1103100)
National Natural Science Foundation of China(32272436)
Key Research and Development Program of Guangdong Province(2022B1111040002)
Affiliations
    1 College of Food Science, South China Agricultural University, Guangzhou 510642, Guangdong, China
    2 National Health Commission Science and Technology Innovation Platform for Nutrition and Safety of Microbial Food, Guangdong Provincial Key Laboratory of Microbial Safety and Health, State Key Laboratory of Applied Microbiology Southern China, Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou 510070, Guangdong, China

Corresponding:

*ZHANG Jumei, E-mail:;
XUE Liang, E-mail:
References
Share
https://castjournals.cast.org.cn/joweb/wswxb/EN/10.13343/j.cnki.wsxb.20230689
Share to
QR

Scan QR to access full text

Cite this article
BibTeX
Citations
表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
关闭全屏
  • BibTeX
  • EndNote
  • RefWorks
  • TxT
Links
Articles
Latest Articles
Most Read
Collections
Updates
Events
News
Multimedia
About
About Us
Contact
No. 86 Xueyuan South Road, Haidian District, Beijing
100081
010-62199257
qkjq@cast.org.cn

Copyright © 2025 China Association for Science and Technology. All rights reserved. For all open access content, the relevant licensing terms apply.
Sponsored by the Office of the Leading Group for Cybersecurity and Informatization of CAST, and supported by Science and Technology Review Publishing House