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Research strategies for the regulatory functions of bacterial transcription factors
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Lingli CHEN1, Xiaofei LI2, Ying LIU1, Fangzhe REN2, Xin’an JIAO3, Jinlin HUANG1, 2, 3, 4
Acta Microbiologica Sinica | 2025, 65(7) : 2864 - 2873
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Acta Microbiologica Sinica | 2025, 65(7): 2864-2873
• Review •
Research strategies for the regulatory functions of bacterial transcription factors
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Lingli CHEN1, Xiaofei LI2, Ying LIU1, Fangzhe REN2, Xin’an JIAO3, Jinlin HUANG1, 2, 3, 4
Affiliations
  • 1.Jiangsu Key Laboratory of Zoonosis, Yangzhou University, Yangzhou, Jiangsu, China
  • 2.Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, Jiangsu, China
  • 3.Key Laboratory of Prevention and Control of Biological Hazard Factors (Animal Origin) for Agrifood Safety and Quality, Ministry of Agriculture and Rural Affairs, Yangzhou, Jiangsu, China
  • 4.Joint International Research Laboratory of Agriculture and Agri-product Safety, Ministry of Education, Yangzhou, Jiangsu, China
Published: 2025-07-04 doi: 10.13343/j.cnki.wsxb.20250019
Outline
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Transcription factors are essential for the survival of bacteria, and revealing their functions is conducive to the development of antimicrobials, industrial applications, and environmental protection. At present, there are many methods and strategies for the research on transcription factors, which have been developed rapidly in the fields of bioinformatics and molecular biology. This paper summarizes the methods for identifying unknown transcription factors, unveiling the regulatory functions of transcription factors, constructing regulatory networks of transcription factors, and validating the regulatory genes of transcription factors. This review aims to provide new strategies and new ideas for the analysis and verification of the regulatory functions of bacterial transcription factors.

bacteria  /  transcription factors  /  regulation  /  bioinformatics
Lingli CHEN, Xiaofei LI, Ying LIU, Fangzhe REN, Xin’an JIAO, Jinlin HUANG. Research strategies for the regulatory functions of bacterial transcription factors[J]. Acta Microbiologica Sinica, 2025 , 65 (7) : 2864 -2873 . DOI: 10.13343/j.cnki.wsxb.20250019
Funding
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  • National Natural Science Foundation of China(32473117)
  • National Key Research and Development Program of China(2024YFC2310300)
Appendix
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Year 2025 volume 65 Issue 7
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170
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Article Info
doi: 10.13343/j.cnki.wsxb.20250019
  • Receive Date：2025-01-08
  • Online Date：2026-02-06
  • Published：2025-07-04
Article Data
Affiliations
History
  • Received：2025-01-08
  • Accepted：2025-02-11
Funding
National Natural Science Foundation of China(32473117)
National Key Research and Development Program of China(2024YFC2310300)
Affiliations
    1.Jiangsu Key Laboratory of Zoonosis, Yangzhou University, Yangzhou, Jiangsu, China
    2.Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, Jiangsu, China
    3.Key Laboratory of Prevention and Control of Biological Hazard Factors (Animal Origin) for Agrifood Safety and Quality, Ministry of Agriculture and Rural Affairs, Yangzhou, Jiangsu, China
    4.Joint International Research Laboratory of Agriculture and Agri-product Safety, Ministry of Education, Yangzhou, Jiangsu, China

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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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