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Research progress in the regulation of blood pressure by gut microbiota
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Bin ZHOU1, Yan HE2, Chenjian LIU1, Xiaoran LI1, *
Acta Microbiologica Sinica | 2025, 65(8) : 3492 - 3506
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Acta Microbiologica Sinica | 2025, 65(8): 3492-3506
• Review •
Research progress in the regulation of blood pressure by gut microbiota
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Bin ZHOU1, Yan HE2, Chenjian LIU1, Xiaoran LI1, *
Affiliations
  • 1.Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, Yunnan, China
  • 2.Hypertension Center, Yan’an Hospital Affiliated to Kunming Medical University, Kunming, Yunnan, China
Published: 2025-08-04 doi: 10.13343/j.cnki.wsxb.20250047
Outline
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As a major risk factor for cardiovascular disease worldwide, hypertension poses threats that cannot be ignored. In recent years, the role of gut microbiota in the pathogenesis of hypertension has gradually become a research hotspot. This review systematically explores the relationship between gut microbiota and hypertension and elaborates on the mechanisms of gut microbiota regulation of blood pressure by mediating inflammatory responses, influencing the microbiota-gut-brain axis, and producing specific metabolites. Furthermore, this article discusses the potential application value of gut microbiota-based intervention strategies in the prevention and treatment of hypertension and reveals the potential targets and evidence of gut microbiota in the treatment of hypertension and its complications, paving a new way for the exploration of therapeutic methods.

gut microbiota  /  hypertension  /  blood pressure regulation
Bin ZHOU, Yan HE, Chenjian LIU, Xiaoran LI. Research progress in the regulation of blood pressure by gut microbiota[J]. Acta Microbiologica Sinica, 2025 , 65 (8) : 3492 -3506 . DOI: 10.13343/j.cnki.wsxb.20250047
Funding
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  • Basic Research Project of Yunnan Provincial Department of Science and Technology(202401AT070846)
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Year 2025 volume 65 Issue 8
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Article Info
doi: 10.13343/j.cnki.wsxb.20250047
  • Receive Date：2025-01-16
  • Online Date：2026-02-06
  • Published：2025-08-04
Article Data
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History
  • Received：2025-01-16
  • Accepted：2025-03-31
Funding
Basic Research Project of Yunnan Provincial Department of Science and Technology(202401AT070846)
Affiliations
    1.Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, Yunnan, China
    2.Hypertension Center, Yan’an Hospital Affiliated to Kunming Medical University, Kunming, Yunnan, China

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*Tel: +86-871-65920759, E-mail:
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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