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Application of artificial intelligence in synthetic biology from the patent perspective
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Qiangyu XIANG1, Lili MA2, Wanying GAO1, Zongzhen WU1, Kunlan ZUO1, Lu ZHANG1, Zexin CHEN3, Jun LI3, Huan LIU1, *
Acta Microbiologica Sinica | 2025, 65(2) : 828 - 845
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Acta Microbiologica Sinica | 2025, 65(2): 828-845
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Application of artificial intelligence in synthetic biology from the patent perspective
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Qiangyu XIANG1, Lili MA2, Wanying GAO1, Zongzhen WU1, Kunlan ZUO1, Lu ZHANG1, Zexin CHEN3, Jun LI3, Huan LIU1, *
Affiliations
  • 1 University of Science and Technology of China, Hefei, Anhui, China
  • 2 National Science Library (Wuhan), Chinese Academy of Sciences, Wuhan, Hubei, China
  • 3 Intellectual Property Development and Research Center, China National Intellectual Property Administration, Beijing, China
Published: 2025-02-04 doi: 10.13343/j.cnki.wsxb.20240572
Outline
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[Objective] To analyze the application trends and distribution of artificial intelligence in synthetic biology from the patent perspective, providing practical insights and theoretical support for technological innovation, research and development (R&D) direction, and industrial layout of this field. [Methods] The paper presents a comprehensive overview of the research contents and methodologies of synthetic biology, and delves into the evolving landscape of artificial intelligence in synthetic biology by extensive patent network mining and literature analysis. [Results] Through thorough examination of pertinent patent data, this study unveils the application patterns and disclosure trends of artificial intelligence in synthetic biology alongside the major countries involved and key applicants. Furthermore, it analyzes the advancements in biosynthetic gene clusters, protein structure analysis, and transcription factor binding sites from the patent perspective. Additionally, this paper expounds the challenges confronting the integration of artificial intelligence into synthetic biology while offering recommendations to address them. [Conclusion] The findings presented herein offer valuable insights into understanding the technical developmental context surrounding artificial intelligence in synthetic biology while serving as a reference for relevant enterprises and research institutions when making R&D decisions. Moreover, this paper underscores the pivotal role played by artificial intelligence in advancing development of synthetic biology while emphasizing its significance. Simultaneously, it provides suggestions to further bolster research efforts on integrating artificial intelligence into synthetic biology with an aim to generate innovative ideas and technical support for constructing national science and technology information systems in global science and technology competition scenarios—particularly concerning advances in synthetic biology.

synthetic biology  /  artificial intelligence  /  patent analysis  /  technical situation  /  science and technology information
Qiangyu XIANG, Lili MA, Wanying GAO, Zongzhen WU, Kunlan ZUO, Lu ZHANG, Zexin CHEN, Jun LI, Huan LIU. Application of artificial intelligence in synthetic biology from the patent perspective[J]. Acta Microbiologica Sinica, 2025 , 65 (2) : 828 -845 . DOI: 10.13343/j.cnki.wsxb.20240572
  • Synthetic Biology National Key Research and Development Program(2024YFA0917200)
  • Construction Project of High-quality Data Pool and Data Product Service System of Chinese Academy of Sciences(2019WQZX012)
  • China National Intellectual Property Administration Synthetic Biology Program(FX202309)
Year 2025 volume 65 Issue 2
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Article Info
doi: 10.13343/j.cnki.wsxb.20240572
  • Receive Date:2024-09-17
  • Online Date:2026-02-05
  • Published:2025-02-04
Article Data
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History
  • Received:2024-09-17
  • Accepted:2024-11-25
Funding
Synthetic Biology National Key Research and Development Program(2024YFA0917200)
Construction Project of High-quality Data Pool and Data Product Service System of Chinese Academy of Sciences(2019WQZX012)
China National Intellectual Property Administration Synthetic Biology Program(FX202309)
Affiliations
    1 University of Science and Technology of China, Hefei, Anhui, China
    2 National Science Library (Wuhan), Chinese Academy of Sciences, Wuhan, Hubei, China
    3 Intellectual Property Development and Research Center, China National Intellectual Property Administration, Beijing, China

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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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