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Research progress in responses and high activity protection mechanisms of lactic acid bacteria under different stresses
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Ning CHEN1, 2, Lei WU2, Xinqiang XIE2, Xinyu ZHAO3, *, Qingping WU2, *
Acta Microbiologica Sinica | 2025, 65(2) : 421 - 436
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Acta Microbiologica Sinica | 2025, 65(2): 421-436
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Research progress in responses and high activity protection mechanisms of lactic acid bacteria under different stresses
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Ning CHEN1, 2, Lei WU2, Xinqiang XIE2, Xinyu ZHAO3, *, Qingping WU2, *
Affiliations
  • 1 College of Food Science, South China Agricultural University, Guangzhou, Guangdong, China
  • 2 State Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Safety and Health, National Health Commission Science and Technology Innovation Platform for Nutrition and Safety of Microbial Food, Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou, Guangdong, China
  • 3 Guangdong Kehuan Biotechnology Co. , Ltd. , Guangzhou, Guangdong, China
Published: 2025-02-04 doi: 10.13343/j.cnki.wsxb.20240596
Outline
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Lactic acid bacteria (LAB) have extensive applications in food and medicine fields. They are used as starters and functional probiotics in food fermentation. The activity and performance of LAB are influenced by various environmental stresses involving osmotic pressure, temperature, oxygen, acidity, and bile salts. Edible LAB can provide numerous health benefits. However, their viable counts decrease during production, storage, and digestion. This paper systematically discusses the different stressful environments faced by LAB during production, storage, and digestion, as well as their stress responses. Furthermore, this paper summarizes existing high activity protection strategies and mechanisms from two aspects: isolating from stressful environments and enhancing strain resistance. This review aims to provide theoretical support for LAB strain engineering and product development.

lactic acid bacteria  /  stress  /  stress response  /  protection mechanism
Ning CHEN, Lei WU, Xinqiang XIE, Xinyu ZHAO, Qingping WU. Research progress in responses and high activity protection mechanisms of lactic acid bacteria under different stresses[J]. Acta Microbiologica Sinica, 2025 , 65 (2) : 421 -436 . DOI: 10.13343/j.cnki.wsxb.20240596
  • National Key Research and Development Program of China(2023YFF1000302)
  • Natural Science Foundation of Guangdong Province(2024A1515010621)
  • Project of Guangdong Academy of Sciences(2022GDASZH-2022010101)
Year 2025 volume 65 Issue 2
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Article Info
doi: 10.13343/j.cnki.wsxb.20240596
  • Receive Date:2024-09-27
  • Online Date:2026-02-05
  • Published:2025-02-04
Article Data
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History
  • Received:2024-09-27
  • Accepted:2024-11-10
Funding
National Key Research and Development Program of China(2023YFF1000302)
Natural Science Foundation of Guangdong Province(2024A1515010621)
Project of Guangdong Academy of Sciences(2022GDASZH-2022010101)
Affiliations
    1 College of Food Science, South China Agricultural University, Guangzhou, Guangdong, China
    2 State Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Safety and Health, National Health Commission Science and Technology Innovation Platform for Nutrition and Safety of Microbial Food, Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou, Guangdong, China
    3 Guangdong Kehuan Biotechnology Co. , Ltd. , Guangzhou, Guangdong, China

Corresponding:

*E-mail: WU Qingping,
ZHAO Xinyu,
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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