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Amino acids serve as indispensable components and nutrients for living organisms, while recent studies have revealed that amino acid metabolism in pathogenic bacteria plays a pivotal role in their pathogenic processes. This review summarizes current research on the roles of different amino acids in facilitating the pathogenicity of pathogenic bacteria. Specifically, we highlight how Salmonella enterica utilizes l-aspartate to achieve colonization and dissemination within the inflamed intestine, and how branched-chain amino acids indirectly regulate the virulence of Staphylococcus aureusvia the global transcriptional regulator CodY. Additionally, we briefly outline the vital roles of amino acid metabolism throughout the infection processes of pathogenic bacteria. In-depth research into how amino acid metabolism promotes pathogenic processes will deepen our understanding of the underlying mechanisms and provide a theoretical basis for developing novel antibacterial strategies.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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