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Endometriosis is a chronic, estrogen-dependent gynecological condition often associated with pelvic pain, dyspareunia, difficulties of defecation and urination, and infertility. The disease poses significant treatment challenges and has a high recurrence rate, causing considerable distress to patients and substantial social and economic impacts. Currently, the exact etiology of endometriosis remains unclear, and the lack of specific biomarkers complicates early diagnosis. Advances in high-throughput sequencing technologies have significantly propelled research into the human microbiome, revealing intricate connections between microbiota and diseases. Notably, the microbiota in the female oral cavity, genital tract, peritoneal cavity, and gut are closely linked to the development and progression of gynecological disorders. This article reviews the correlations between the human microbiome and endometriosis and explores the potential applications of microbiota in the diagnosis and treatment of endometriosis.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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