Article(id=1261728984065237039, tenantId=1146029695717560320, journalId=1146119944283992078, issueId=1261728796072358112, articleNumber=null, orderNo=null, doi=null, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1778749231592, onlineDateStr=2026-05-14, pubDate=1774195200000, pubDateStr=2026-03-23, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1778749231592, onlineIssueDateStr=2026-05-14, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1778749231592, creator=13701087609, updateTime=1778749231592, updator=13701087609, issue=Issue{id=1261728796072358112, tenantId=1146029695717560320, journalId=1146119944283992078, year='2026', volume='4', issue='6', pageStart='1', pageEnd='234', issueExtLink='null', onlineDate='null', pubDate='null', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=1, specialIssue=null, createTime=1778749186771, creator=13701087609, updateTime=1778750183088, updator=13701087609, preIssue=null, nextIssue=null, ext={EN=IssueExt(id=1261732975067148479, tenantId=1146029695717560320, journalId=1146119944283992078, issueId=1261728796072358112, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1261732975071342784, tenantId=1146029695717560320, journalId=1146119944283992078, issueId=1261728796072358112, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null}, startPage=184, endPage=188, ext={CN=ArticleExt(id=1261728987559092294, articleId=1261728984065237039, tenantId=1146029695717560320, journalId=1146119944283992078, language=CN, title=紫外分光光度法快速测定盐酸二甲双胍缓释片中盐酸二甲双胍含量, columnId=1261728976733594600, journalTitle=实验室检测, columnName=分析与检测, runingTitle=null, highlight=null, articleAbstract=
目的

建立一种准确快速、安全环保的紫外分光光度法(ultraviolet spectrophotometry, UV)用于测定盐酸二甲双胍(metformin hydrochloride, MET)缓释片中MET的含量。

方法

采用UV测定MET含量,检测波长为233 nm。以水为溶剂,采用标准曲线法定量,供试品溶液中约含5 μg/mL盐酸二甲双胍。

结果

MET质量浓度在0~9.800 μg/mL范围内线性良好,回归方程为Y=12.6083X+0.0047,r=0.99999727,平均回收率100.75%,相对标准偏差(relative standard deviation, RSD)为1.26%,重复性(RSD=0.41%)、中间精密度(RSD=0.38%)良好,MET缓释片及对照品均能在10 h内稳定。本实验研究方法与高效液相色谱(high performance liquid chromatography, HPLC)法对MET缓释片中MET的含量测定结果一致。

结论

本研究建立方法操作简单方便,准确可靠且安全环保,可作为HPLC法的有效补充,适用于大批量快速测定MET缓释片中MET的含量。关键词:紫外分光光度法;盐酸二甲双胍;缓释片

, correspAuthors=马明, authorNote=null, correspAuthorsNote=

*

马明,硕士,副教授,主要研究方向为药物分析教学质量研究与药品质量控制。E-mail:
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唐利宇,硕士,讲师,主要研究方向为分析化学教科研。E-mail:

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唐利宇,硕士,讲师,主要研究方向为分析化学教科研。E-mail:

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紫外分光光度法快速测定盐酸二甲双胍缓释片中盐酸二甲双胍含量
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唐利宇 1 , 陈月琴 1 , 徐樱莹 1 , 沈霖 1 , 张文琦 1 , 何婷婷 1 , 向龙 2 , 马明 1, *
实验室检测 | 分析与检测 2026,4(6): 184-188
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实验室检测 | 分析与检测 2026, 4(6): 184-188
紫外分光光度法快速测定盐酸二甲双胍缓释片中盐酸二甲双胍含量
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唐利宇1 , 陈月琴1, 徐樱莹1, 沈霖1, 张文琦1, 何婷婷1, 向龙2, 马明1, *
作者信息
  • 1.江苏联合职业技术学院无锡卫生分院,无锡卫生高等职业技术学校,无锡 214000
  • 2.无锡检验检测认证研究院,无锡 214000
  • 唐利宇,硕士,讲师,主要研究方向为分析化学教科研。E-mail:

通讯作者:

*

马明,硕士,副教授,主要研究方向为药物分析教学质量研究与药品质量控制。E-mail:
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出版时间: 2026-03-23
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目的

建立一种准确快速、安全环保的紫外分光光度法(ultraviolet spectrophotometry, UV)用于测定盐酸二甲双胍(metformin hydrochloride, MET)缓释片中MET的含量。

方法

采用UV测定MET含量,检测波长为233 nm。以水为溶剂,采用标准曲线法定量,供试品溶液中约含5 μg/mL盐酸二甲双胍。

结果

MET质量浓度在0~9.800 μg/mL范围内线性良好,回归方程为Y=12.6083X+0.0047,r=0.99999727,平均回收率100.75%,相对标准偏差(relative standard deviation, RSD)为1.26%,重复性(RSD=0.41%)、中间精密度(RSD=0.38%)良好,MET缓释片及对照品均能在10 h内稳定。本实验研究方法与高效液相色谱(high performance liquid chromatography, HPLC)法对MET缓释片中MET的含量测定结果一致。

结论

本研究建立方法操作简单方便,准确可靠且安全环保,可作为HPLC法的有效补充,适用于大批量快速测定MET缓释片中MET的含量。关键词:紫外分光光度法;盐酸二甲双胍;缓释片

唐利宇, 陈月琴, 徐樱莹, 沈霖, 张文琦, 何婷婷, 向龙, 马明. 紫外分光光度法快速测定盐酸二甲双胍缓释片中盐酸二甲双胍含量. 实验室检测, 2026 , 4 (6) : 184 -188 .
  • 无锡卫生健康委面上科研项目(M202444)
  • 无锡卫生高等职业技术学校教科研课题项目(XWZJ-2501)
2026年第4卷第6期
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  • 首发时间:2026-05-14
  • 出版时间:2026-03-23
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基金
无锡卫生健康委面上科研项目(M202444)
无锡卫生高等职业技术学校教科研课题项目(XWZJ-2501)
作者信息
    1.江苏联合职业技术学院无锡卫生分院,无锡卫生高等职业技术学校,无锡 214000
    2.无锡检验检测认证研究院,无锡 214000

通讯作者:

*

马明,硕士,副教授,主要研究方向为药物分析教学质量研究与药品质量控制。E-mail:
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2种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
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Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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