Article(id=1156967536202961854, tenantId=1146029695717560320, journalId=1146119944283992078, issueId=1156967523842347919, articleNumber=null, orderNo=null, doi=null, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1753772156047, onlineDateStr=2025-07-29, pubDate=null, pubDateStr=null, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1753772156047, onlineIssueDateStr=2025-07-29, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1753772156047, creator=13701087609, updateTime=1753772156047, updator=13701087609, issue=Issue{id=1156967523842347919, tenantId=1146029695717560320, journalId=1146119944283992078, year='2024', volume='2', issue='7', pageStart='1', pageEnd='160', issueExtLink='null', onlineDate='null', pubDate='null', beforeIssueId=null, nextIssueId=null, price=null, status=0, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1753772153100, creator=13701087609, updateTime=1753777984529, updator=13701087609, preIssue=null, nextIssue=null, ext={EN=IssueExt(id=1156991982682854377, tenantId=1146029695717560320, journalId=1146119944283992078, issueId=1156967523842347919, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1156991982682854378, tenantId=1146029695717560320, journalId=1146119944283992078, issueId=1156967523842347919, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null}, startPage=41, endPage=44, ext={EN=ArticleExt(id=1156967538044261313, articleId=1156967536202961854, tenantId=1146029695717560320, journalId=1146119944283992078, language=EN, title=Application research of blood smear cell morphology and fully automatic blood cell analyzer in blood routine testing, columnId=1156641065621906129, journalTitle=Laboratory Testing, columnName=Innovative Applications, runingTitle=null, highlight=null, articleAbstract=
Objective To study the application of cell morphology inblood smear and automatic blood cell analyzer detection in blood routineexamination. Methods A analys was was conducted on 180 patients withsuspected Macrocellular anemia at Yishui County People’s Hospital fromFebruary 2020 to February 2023. The positive detection rates of diseasewere statwastically analyzed for individual and combined tests, and thepositive detection rates of toxic particles/vacuolar degeneration,nucleated red blood cells, and atypical lymphocytes were alsostatwastically analyzed for individual and combined tests, statwasticalanalyswas of diagnostic efficacy for individual and joint testing. Results The positive detection rates of monocytes, neutrophils,lymphocytes, basophils, and eosinophils detected by the combination ofblood smear cell morphology and fully automated blood cell analyzer werehigher than those detected alone $\left({P<{0.05}}\right)$ . The positive detection rates of toxicparticle/vacuolar degeneration, nucleated red blood cells, and atypicallymphocytes detected by the combination of blood smear cell morphologyand fully automated blood cell analyzer were higher than those detectedalone $\left({P <{0.05}}\right)$ .The sensitivity, specificity, accuracy, and negative predictive value ofthe combined detection of blood smear cell morphology and fullyautomated blood cell analyzer were higher than those of individualdetection $\left({P<{0.05}}\right)$ . Conclusion The value of combined detectionof blood smear cell morphology and fully automated blood cell analyzerin blood routine examination is higher, so is worthy of promotion.
, correspAuthors=Wan-Ju SUN, authorNote=null, correspAuthorsNote=
*SUN Wan-Ju, Master, Chief Technician, Laboratory Department of Yishui County People's Hospital, Linyi 276400, China. E-mail:
bysunwanjv@163.com, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, authorCompany=null, fund=null, authors=null, authorsList=Chun-Jing LI, Wan-Ju SUN, Li-Li ZHANG), CN=ArticleExt(id=1156967538333668291, articleId=1156967536202961854, tenantId=1146029695717560320, journalId=1146119944283992078, language=CN, title=全自动血细胞分析仪与血涂片细胞形态学在血常规检验中的应用研究, columnId=1151957373175820401, journalTitle=实验室检测, columnName=创新应用, runingTitle=null, highlight=null, articleAbstract=
目的 研究全自动血细胞分析仪、血涂片细胞形态学检测在血常规检验中的应用。方法 选取 2020 年 2 月 - 2023 年 2 月沂水县人民医院疑似大细胞性贫血患者 180例,统计分析单独与联合检测疾病阳性检出情况,并统计分析单独与联合检测中毒颗粒/空泡变性、异型淋巴细胞、有核红细胞阳性检出情况,统计分析单独与联合检测诊断效能。结果 联合检测单核细胞、中性粒细胞、淋巴细胞、嗜酸性细胞、嗜碱性细胞阳性检出率、中毒颗粒给泡变性、异型淋巴细胞、有核红细胞阳性检出率均高于单独检测( $P<{0.05}$ )。联合检测的灵敏性、特异性、准确性、阴性预测值均高于单独检测( $P<{0.05}$ )。结论 全自动血细胞分析仪、血涂片细胞形态学联合检测在血常规检验中的价值较高,值得推广。
, correspAuthors=孙万菊, authorNote=null, correspAuthorsNote=
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孙万菊,硕士,主管技师,研究方向为临床微生物学检验。
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9(05): 96-98., articleTitle=血液涂片细胞形态学联合全自动血细胞分析仪在血常规检验中的应用, refAbstract=null), Reference(id=1156967573247054120, tenantId=1146029695717560320, journalId=1146119944283992078, articleId=1156967536202961854, doi=null, pmid=null, pmcid=null, year=2019, volume=25, issue=23, pageStart=152, pageEnd=153, url=null, language=null, rfNumber=[11], rfOrder=10, authorNames=钟春燕, journalName=中国医疗器械信息, refType=null, unstructuredReference=钟春燕. 探讨全自动血细胞分析仪与血涂片细胞形态学在血常规检验中的联合应用[J].
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25(23): 152-153., articleTitle=探讨全自动血细胞分析仪与血涂片细胞形态学在血常规检验中的联合应用, refAbstract=null), Reference(id=1156967573330940203, tenantId=1146029695717560320, journalId=1146119944283992078, articleId=1156967536202961854, doi=null, pmid=null, pmcid=null, year=2019, volume=25, issue=04, pageStart=52, pageEnd=126, url=null, language=null, rfNumber=[12], rfOrder=11, authorNames=吕铁仁, journalName=中国医疗器械信息, refType=null, unstructuredReference=吕铁仁. 全自动血细胞分析仪联合血涂片细胞形态学在血常规检验中的应用效果[J].
中国医疗器械信息,
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25(04): 52-126., articleTitle=全自动血细胞分析仪联合血涂片细胞形态学在血常规检验中的应用效果, refAbstract=null), Reference(id=1156967573398049070, tenantId=1146029695717560320, journalId=1146119944283992078, articleId=1156967536202961854, doi=null, pmid=null, pmcid=null, year=2019, volume=25, issue=23, pageStart=154, pageEnd=155, url=null, language=null, rfNumber=[13], rfOrder=12, authorNames=孙亚杰, journalName=中国医疗器械信息, refType=null, unstructuredReference=孙亚杰. 血液涂片细胞形态学与全自动血细胞分析仪联合应用于血常规检验中的效果分析[J].
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2019,
25(23): 154-155., articleTitle=血液涂片细胞形态学与全自动血细胞分析仪联合应用于血常规检验中的效果分析, refAbstract=null), Reference(id=1156967573452575024, tenantId=1146029695717560320, journalId=1146119944283992078, articleId=1156967536202961854, doi=null, pmid=null, pmcid=null, year=2019, volume=32, issue=24, pageStart=49, pageEnd=50, url=null, language=null, rfNumber=[14], rfOrder=13, authorNames=雷慧娟, journalName=医疗装备, refType=null, unstructuredReference=雷慧娟. 全自动血细胞分析仪联合血涂片细胞形态学在血常规检验中的应用效果[J].
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32(24): 49-50., articleTitle=全自动血细胞分析仪联合血涂片细胞形态学在血常规检验中的应用效果, refAbstract=null), Reference(id=1156967573511295282, tenantId=1146029695717560320, journalId=1146119944283992078, articleId=1156967536202961854, doi=null, pmid=null, pmcid=null, year=2019, volume=25, issue=07, pageStart=140, pageEnd=141, url=null, language=null, rfNumber=[15], rfOrder=14, authorNames=吴琼, journalName=中国医疗器械信息, refType=null, unstructuredReference=吴琼. 全自动血细胞分析仪与血涂片细胞形态学在血常规检验中的应用价值[J].
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25(07): 140-141., articleTitle=全自动血细胞分析仪与血涂片细胞形态学在血常规检验中的应用价值, refAbstract=null)], funds=null, companyList=[AuthorCompany(id=1156967566695551187, tenantId=1146029695717560320, journalId=1146119944283992078, articleId=1156967536202961854, xref=null, ext=[AuthorCompanyExt(id=1156967566699745492, tenantId=1146029695717560320, journalId=1146119944283992078, articleId=1156967536202961854, companyId=1156967566695551187, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=Laboratory Department Yishui County People's Hospital Linyi 276400 China), AuthorCompanyExt(id=1156967567232422101, tenantId=1146029695717560320, journalId=1146119944283992078, articleId=1156967536202961854, companyId=1156967566695551187, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=沂水县人民医院 检验科 临沂 276400)])], figs=[ArticleFig(id=1156967571686773001, tenantId=1146029695717560320, journalId=1146119944283992078, articleId=1156967536202961854, language=EN, label=Table 1, caption=
Comparison of positive detection of diseases between individual and joint testing [n (%)], figureFileSmall=null, figureFileBig=null, tableContent=
| 组别 | n | 单核细胞 | 中性粒细胞 | 淋巴细胞 |
| 全自动血细胞分析仪 | 180 | 136 ( 75.56 ) | 146 ( 81.11 ) | 156 ( 86.67 ) |
| 血涂片细胞形态学 | 180 | 140 ( 77.78 ) | 140 ( 77.78 ) | 150 (83.33) |
| 联合检测 | 180 | 172 ( 95.56 ) | 176 ( 97.78 ) | 180 ( 100.00 ) |
| ${\chi }^{2}$ 值 | - | 30.606 | 33.447 | 31.111 |
| $p$ 值 | - | <0.001 | <0.001 | <0.001 |
), ArticleFig(id=1156967571749687562, tenantId=1146029695717560320, journalId=1146119944283992078, articleId=1156967536202961854, language=CN, label=表 1, caption=
单独与联合检测疾病阳性检出情况比较 $\left\lbrack {\mathrm{n}\left(\%\right)}\right\rbrack$, figureFileSmall=null, figureFileBig=null, tableContent=
| 组别 | n | 单核细胞 | 中性粒细胞 | 淋巴细胞 |
| 全自动血细胞分析仪 | 180 | 136 ( 75.56 ) | 146 ( 81.11 ) | 156 ( 86.67 ) |
| 血涂片细胞形态学 | 180 | 140 ( 77.78 ) | 140 ( 77.78 ) | 150 (83.33) |
| 联合检测 | 180 | 172 ( 95.56 ) | 176 ( 97.78 ) | 180 ( 100.00 ) |
| ${\chi }^{2}$ 值 | - | 30.606 | 33.447 | 31.111 |
| $p$ 值 | - | <0.001 | <0.001 | <0.001 |
), ArticleFig(id=1156967571837767947, tenantId=1146029695717560320, journalId=1146119944283992078, articleId=1156967536202961854, language=EN, label=Table 2, caption=
Comparison of positive detection of diseases between individual and joint testing $\left\lbrack {\mathrm{n}\left(\%\right)}\right\rbrack$, figureFileSmall=null, figureFileBig=null, tableContent=
| 组别 | n | 嗜碱性细胞 | 嗜酸性细胞 |
| 全自动血细胞分析仪 | 180 | 130 (72.22) | 126 ( 70.00 ) |
| 血涂片细胞形态学 | 180 | 132 (73.33) | 138 ( 76.67 ) |
| 联合检测 | 180 | 164 ( 91.11 ) | 168 (93.33 ) |
| ${\chi }^{2}$ 值 | - | 59.939 | 32.500 |
| $P$ 值 | - | <0.001 | <0.001 |
), ArticleFig(id=1156967571925848332, tenantId=1146029695717560320, journalId=1146119944283992078, articleId=1156967536202961854, language=CN, label=表 2, caption=
单独与联合检测疾病阳性检出情况比较 $\left\lbrack {\mathrm{n}\left(\%\right)}\right\rbrack$, figureFileSmall=null, figureFileBig=null, tableContent=
| 组别 | n | 嗜碱性细胞 | 嗜酸性细胞 |
| 全自动血细胞分析仪 | 180 | 130 (72.22) | 126 ( 70.00 ) |
| 血涂片细胞形态学 | 180 | 132 (73.33) | 138 ( 76.67 ) |
| 联合检测 | 180 | 164 ( 91.11 ) | 168 (93.33 ) |
| ${\chi }^{2}$ 值 | - | 59.939 | 32.500 |
| $P$ 值 | - | <0.001 | <0.001 |
), ArticleFig(id=1156967572018123022, tenantId=1146029695717560320, journalId=1146119944283992078, articleId=1156967536202961854, language=EN, label=Table 3, caption=
Comparison of positive detection of toxic particles/vacuolar degeneration, atypical lymphocytes, and nucleated red blood cells between individual and joint testing $\left\lbrack \left({\mathrm{n}\%}\right)\right\rbrack$, figureFileSmall=null, figureFileBig=null, tableContent=
| 组别 | $\mathrm{n}$ | 中毒颗粒/空泡变性 | 有核红细胞 | 异型淋巴细胞 |
| 全自动血细胞分析仪 | 180 | 136 ( 75.56 ) | 114 ( 63.33 ) | 124 ( 68.89 ) |
| 血涂片细胞形态学 | 180 | 142 ( 78.89 ) | 128 ( 71.11 ) | 142 ( 78.89 ) |
| 联合检测 | 180 | 170 ( 94.44 ) | 164 ( 91.11 ) | 176 ( 97.78 ) |
| ${\chi }^{2}$ 值 | - | 25.889 | 39.624 | 52.160 |
| P 值 | - | <0.001 | <0.001 | <0.001 |
), ArticleFig(id=1156967572081037585, tenantId=1146029695717560320, journalId=1146119944283992078, articleId=1156967536202961854, language=CN, label=表 3, caption=
单独与联合检测中毒颗粒/空泡变性、异型淋巴细胞、有核红细胞阳性检出情况比较 $\left\lbrack \left({\mathrm{n}\%}\right)\right\rbrack$, figureFileSmall=null, figureFileBig=null, tableContent=
| 组别 | $\mathrm{n}$ | 中毒颗粒/空泡变性 | 有核红细胞 | 异型淋巴细胞 |
| 全自动血细胞分析仪 | 180 | 136 ( 75.56 ) | 114 ( 63.33 ) | 124 ( 68.89 ) |
| 血涂片细胞形态学 | 180 | 142 ( 78.89 ) | 128 ( 71.11 ) | 142 ( 78.89 ) |
| 联合检测 | 180 | 170 ( 94.44 ) | 164 ( 91.11 ) | 176 ( 97.78 ) |
| ${\chi }^{2}$ 值 | - | 25.889 | 39.624 | 52.160 |
| P 值 | - | <0.001 | <0.001 | <0.001 |
), ArticleFig(id=1156967572152340755, tenantId=1146029695717560320, journalId=1146119944283992078, articleId=1156967536202961854, language=EN, label=Table 4, caption=
Comparison of diagnostic performance between individual and joint testing [(n%)], figureFileSmall=null, figureFileBig=null, tableContent=
| 检测方法 | 结果 | 临床确诊 |
| 全自动血细胞分析仪 | - | 阳性 | 阴性 | 合计 |
| 阳性 | 132 | 4 | 136 |
| 阴性 | 28 | 16 | 44 |
| 合计 | 160 | 20 | 180 |
| 血涂片细胞形态学 | 阳性 | 130 | 3 | 133 |
| 阴性 | 30 | 17 | 47 |
| 合计 | 160 | 20 | 180 |
| 联合检测 | 阳性 | 155 | 1 | 156 |
| 阴性 | 5 | 19 | 24 |
| 合计 | 160 | 20 | 180 |
), ArticleFig(id=1156967572232032533, tenantId=1146029695717560320, journalId=1146119944283992078, articleId=1156967536202961854, language=CN, label=表 4, caption=
单独与联合检测诊断效能比较 $\left\lbrack \left({\mathrm{n}\%}\right)\right\rbrack$, figureFileSmall=null, figureFileBig=null, tableContent=
| 检测方法 | 结果 | 临床确诊 |
| 全自动血细胞分析仪 | - | 阳性 | 阴性 | 合计 |
| 阳性 | 132 | 4 | 136 |
| 阴性 | 28 | 16 | 44 |
| 合计 | 160 | 20 | 180 |
| 血涂片细胞形态学 | 阳性 | 130 | 3 | 133 |
| 阴性 | 30 | 17 | 47 |
| 合计 | 160 | 20 | 180 |
| 联合检测 | 阳性 | 155 | 1 | 156 |
| 阴性 | 5 | 19 | 24 |
| 合计 | 160 | 20 | 180 |
), ArticleFig(id=1156967572299141399, tenantId=1146029695717560320, journalId=1146119944283992078, articleId=1156967536202961854, language=EN, label=Table 5, caption=
Comparison of diagnostic efficiency between individual and joint testing [(n%)], figureFileSmall=null, figureFileBig=null, tableContent=
| 组别 | n | 灵敏性 | 特异性 | 准确性 | 阳性预测值 | 阴性预测值 |
| 全自动血细胞分析仪 | 180 | 82.50 | 80.00 | 82.22 | 97.06 | 36.36 |
| 血涂片细胞形态学 | 180 | 81.25 | 85.00 | 81.67 | 97.74 | 36.17 |
| 联合检测 | 180 | 96.88 | 95.00 | 96.67 | 99.36 | 79.17 |
| ${\chi }^{2}$ 值 | - | 11.140 | 12.830 | 11.340 | 1.320 | 14.450 |
| $P$ 值 | - | <0.05 | <0.05 | <0.05 | >0.05 | <0.05 |
), ArticleFig(id=1156967572362055960, tenantId=1146029695717560320, journalId=1146119944283992078, articleId=1156967536202961854, language=CN, label=表 5, caption=
单独与联合检测诊断效能比较 [(n%)], figureFileSmall=null, figureFileBig=null, tableContent=
| 组别 | n | 灵敏性 | 特异性 | 准确性 | 阳性预测值 | 阴性预测值 |
| 全自动血细胞分析仪 | 180 | 82.50 | 80.00 | 82.22 | 97.06 | 36.36 |
| 血涂片细胞形态学 | 180 | 81.25 | 85.00 | 81.67 | 97.74 | 36.17 |
| 联合检测 | 180 | 96.88 | 95.00 | 96.67 | 99.36 | 79.17 |
| ${\chi }^{2}$ 值 | - | 11.140 | 12.830 | 11.340 | 1.320 | 14.450 |
| $P$ 值 | - | <0.05 | <0.05 | <0.05 | >0.05 | <0.05 |
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