Article(id=1153433635819606722, tenantId=1146029695717560320, journalId=1149652044408987649, issueId=1153433633999282214, articleNumber=null, orderNo=null, doi=10.19812/j.cnki.jfsq11-5956/ts.20241118007, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1731859200000, receivedDateStr=2024-11-18, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1752929608539, onlineDateStr=2025-07-19, pubDate=1742832000000, pubDateStr=2025-03-25, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1752929608539, onlineIssueDateStr=2025-07-19, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1752929608539, creator=13701087609, updateTime=1752929608539, updator=13701087609, issue=Issue{id=1153433633999282214, tenantId=1146029695717560320, journalId=1149652044408987649, year='2025', volume='16', issue='6', pageStart='1', pageEnd='322', issueExtLink='null', onlineDate='null', pubDate='null', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=0, createTime=1752929608105, creator=13701087609, updateTime=1758086445549, updator=13701087609, preIssue=null, nextIssue=null, ext={EN=IssueExt(id=1175062977960096080, tenantId=1146029695717560320, journalId=1149652044408987649, issueId=1153433633999282214, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1175062977960096081, tenantId=1146029695717560320, journalId=1149652044408987649, issueId=1153433633999282214, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null}, startPage=52, endPage=58, ext={EN=ArticleExt(id=1153433636213871303, articleId=1153433635819606722, tenantId=1146029695717560320, journalId=1149652044408987649, language=EN, title=Contamination level and dietary exposure assessment of glycidyl esters in edible vegetable oils sold in Shanghai, columnId=1151923892655846010, journalTitle=Journal of Food Safety & Quality, columnName=Special Topic: Food Safety Risk Assessment and Risk Monitoring, runingTitle=null, highlight=null, articleAbstract=

Objective To understand the contamination level of glycidyl esters (GE) in edible vegetable oils and to evaluate the dietary exposure risk of GE in Shanghai residents. Methods Based on the monitoring data of GE in edible vegetable oil sold in Shanghai in 2024, combined with the vegetable oil consumption data of Shanghai residents in 2024, the GE exposure of Shanghai residents via vegetable oil was calculated by simple distribution assessment method, and the margin of exposure (MOE) method was used to assess the health risk. Results The detection rate of GE in 178 edible vegetable oils was 94.4%, with an average content of 360.8 μg/kg and a maximum value of 5470.0 μg/kg. According to the EU regulations on the limit values of GE in vegetable oils, it was found that the exceeding standard rate of GE in vegetable oil was 5.6%. The mean content of GE in rice oil (1169.3 μg/kg) was the highest, followed by camellia seed oil (657.8 μg/kg) and corn oil (499.0 μg/kg). The mean daily exposure and 95th percentile exposure of GE from edible vegetable oils in Shanghai residents aged ≥3 years old were 0.208 and 0.497 μg/kg bw, the MOE values were 11538 and 4829, respectively, and P95 MOE was less than 10000. The mean MOE value of GE exposure through vegetable oil in residents aged 3 to 17 years old was less than 10000. The P95 MOE values of GE exposure through vegetable oil in 4 different age groups were all less than 10000. Conclusion The health risk of GE intake via edible vegetable oil in Shanghai residents is generally at an acceptable level. However, the health risks of GE exposure for individuals aged 3 to 17 year old and those with high consumption of vegetable oil still need to be focused.

, correspAuthors=Shao-Jie PENG, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, authorCompany=null, fund=null, authors=null, authorsList=Sheng-Hao YU, Shao-Jie PENG), CN=ArticleExt(id=1153433644761863124, articleId=1153433635819606722, tenantId=1146029695717560320, journalId=1149652044408987649, language=CN, title=上海市市售食用植物油中缩水甘油酯的污染水平和膳食暴露评估, columnId=1152687438456603210, journalTitle=食品安全质量检测学报, columnName=本期专题:食品安全风险评估与风险监测, runingTitle=null, highlight=null, articleAbstract=

目的 了解上海居民食用植物油中缩水甘油酯(glycidyl esters, GE)的污染水平, 评估上海居民GE的膳食暴露风险。方法 利用2024年上海市市售食用植物油中GE的监测数据, 结合2024年上海居民植物油消费量数据, 采用简单分布评估法计算上海居民经植物油摄入GE的暴露量, 并用暴露边界比(margin of exposure, MOE)法评估健康风险。结果 178件食用植物油中GE的检出率为94.4%, 含量均值为360.8 μg/kg, 最大值为5470.0 μg/kg。参照欧盟法规规定的植物油中GE的限量值进行评价, 发现样品中GE的超标率为5.6%。稻米油中GE的含量均值(1169.3 μg/kg)最高, 其次为油茶籽油(657.8 μg/kg)和玉米油(499.0 μg/kg)。上海≥3岁居民每日通过食用植物油摄入GE的平均暴露量和P95暴露量分别为0.208和0.497 μg/kg bw, MOE值分别为11538和4829, P95 MOE小于10000。3~17岁居民经植物油摄入GE的平均MOE值小于10000。4个不同年龄组居民经植物油摄入GE的P95 MOE值均小于10000。结论 上海居民经植物油摄入GE的健康风险总体上处于可接受水平。但对于3~17岁人群以及植物油高消费人群GE暴露的健康风险仍需重点关注。

, correspAuthors=彭少杰, authorNote=null, correspAuthorsNote=
* 彭少杰(1968—), 男, 硕士, 主任医师, 主要研究方向为食品安全风险监测与评估。E-mail:
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宇盛好(1990—), 男, 硕士, 工程师, 主要研究方向为食品安全风险监测与评估。E-mail:

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[2024-04-23]. https://doi.org/10.19902/j.cnki.zgyz.1003-7969.240061 , articleTitle=酶催化酯化法降低模型油中甘油一酯和甘油二酯以防控3-氯丙醇酯和缩水甘油酯的研究, refAbstract=null), Reference(id=1175086853783962352, tenantId=1146029695717560320, journalId=1149652044408987649, articleId=1153433635819606722, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=1, pageEnd=18, url=null, language=null, rfNumber=[29], rfOrder=41, authorNames=FENG ZH, ZHOU YX, SUN SD, journalName=China Oils and Fats, refType=null, unstructuredReference=FENG ZH, ZHOU YX, SUN SD. Study on reducing monoglyceride and diglyceride of model oil by enzyme esterification to control 3-monochloropropane-1,2-diol esters and glycidyl esters[J/OL]. China Oils and Fats, 1-18. [2024-04-23]. https://doi.org/10.19902/j.cnki.zgyz.1003-7969.240061, articleTitle=Study on reducing monoglyceride and diglyceride of model oil by enzyme esterification to control 3-monochloropropane-1,2-diol esters and glycidyl esters, refAbstract=null), Reference(id=1175086853913985778, tenantId=1146029695717560320, journalId=1149652044408987649, articleId=1153433635819606722, doi=null, pmid=null, pmcid=null, year=2021, volume=46, issue=5, pageStart=97, pageEnd=102, url=null, language=null, rfNumber=[30], rfOrder=42, authorNames=李利君, 李加辛, 马传国, journalName=中国油脂, refType=null, unstructuredReference=李利君, 李加辛, 马传国. 脱臭温度下油脂成分对3-氯丙醇酯和缩水甘油酯形成的影响及其形成机理的推测[J]. 中国油脂, 2021, 46(5): 97-102., articleTitle=脱臭温度下油脂成分对3-氯丙醇酯和缩水甘油酯形成的影响及其形成机理的推测, refAbstract=null), Reference(id=1175086853981094644, tenantId=1146029695717560320, journalId=1149652044408987649, articleId=1153433635819606722, doi=null, pmid=null, pmcid=null, year=2021, volume=46, issue=5, pageStart=97, pageEnd=102, url=null, language=null, rfNumber=[30], rfOrder=43, authorNames=LI LJ, LI JX, MA CG, journalName=China Oils and Fats, refType=null, unstructuredReference=LI LJ, LI JX, MA CG. Influence of oil components on the formation of 3-monochloropropane-1, 2 -diol esters and glycidyl esters and speculation about the formation mechanism under the simulated deodorization temperature[J]. China Oils and Fats, 2021, 46(5): 97-102., articleTitle=Influence of oil components on the formation of 3-monochloropropane-1, 2 -diol esters and glycidyl esters and speculation about the formation mechanism under the simulated deodorization temperature, refAbstract=null), Reference(id=1175086854073369334, tenantId=1146029695717560320, journalId=1149652044408987649, articleId=1153433635819606722, doi=null, pmid=null, pmcid=null, year=2021, volume=11, issue=27, pageStart=16500, pageEnd=16509, url=null, language=null, rfNumber=[31], rfOrder=44, authorNames=RESTIAWATY E, MAULANA A, UMI-CULSUM NT, journalName=RSC Advances, refType=null, unstructuredReference=RESTIAWATY E, MAULANA A, UMI-CULSUM NT, et al. The removal of 3-monochloropropane-1,2-diol ester and glycidyl ester from refined-bleached and deodorized palm oil using activated carbon[J]. RSC Advances, 2021, 11(27): 16500-16509., articleTitle=The removal of 3-monochloropropane-1,2-diol ester and glycidyl ester from refined-bleached and deodorized palm oil using activated carbon, refAbstract=null), Reference(id=1175086854153061111, tenantId=1146029695717560320, journalId=1149652044408987649, articleId=1153433635819606722, doi=null, pmid=null, pmcid=null, year=2022, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[32], rfOrder=45, authorNames=安浩, journalName=葵花籽油加工过程中3-氯丙醇酯和缩水甘油酯的形成及抑制研究, refType=null, unstructuredReference=安浩. 葵花籽油加工过程中3-氯丙醇酯和缩水甘油酯的形成及抑制研究[D]. 郑州: 河南工业大学, 2022., articleTitle=null, refAbstract=null), Reference(id=1175086854236947193, tenantId=1146029695717560320, journalId=1149652044408987649, articleId=1153433635819606722, doi=null, pmid=null, pmcid=null, year=2022, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[32], rfOrder=46, authorNames=AN H, journalName=Formation and inhibition of 3-chloro-1,2-propanediol fatty acid esters and glycidyl esters during processing in sunflower oil, refType=null, unstructuredReference=AN H. Formation and inhibition of 3-chloro-1,2-propanediol fatty acid esters and glycidyl esters during processing in sunflower oil[D]. Zhengzhou: Henan University of Technology, 2022., articleTitle=null, refAbstract=null)], funds=[Fund(id=1175086849782596256, tenantId=1146029695717560320, journalId=1149652044408987649, articleId=1153433635819606722, awardId=2024-51, language=CN, fundingSource=2024年度上海市市场监督管理局科技项目(2024-51), fundOrder=null, country=null)], companyList=[AuthorCompany(id=1175086846800446013, tenantId=1146029695717560320, journalId=1149652044408987649, articleId=1153433635819606722, xref=null, ext=[AuthorCompanyExt(id=1175086846804640318, tenantId=1146029695717560320, journalId=1149652044408987649, articleId=1153433635819606722, companyId=1175086846800446013, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=Information Application Research Center of Shanghai Municipal Administration for Market Regulation, Shanghai 200030, China), AuthorCompanyExt(id=1175086846813028927, tenantId=1146029695717560320, journalId=1149652044408987649, articleId=1153433635819606722, companyId=1175086846800446013, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=上海市市场监督管理局信息应用研究中心, 上海 200030)])], figs=[ArticleFig(id=1175086848499139190, tenantId=1146029695717560320, journalId=1149652044408987649, articleId=1153433635819606722, language=EN, label=Fig.1, caption=Frequency distribution of GE content in edible vegetable oils, figureFileSmall=UgqTcbjcg8K7oquMBcDxDg==, figureFileBig=+E3pUa9ggs2+TbVWwo+T2A==, tableContent=null), ArticleFig(id=1175086848566248057, tenantId=1146029695717560320, journalId=1149652044408987649, articleId=1153433635819606722, language=CN, label=图1, caption=食用植物油中GE含量的频数分布图, figureFileSmall=UgqTcbjcg8K7oquMBcDxDg==, figureFileBig=+E3pUa9ggs2+TbVWwo+T2A==, tableContent=null), ArticleFig(id=1175086848767574650, tenantId=1146029695717560320, journalId=1149652044408987649, articleId=1153433635819606722, language=EN, label=Table 1, caption=

Contamination levels of GE in different types of edible vegetable oils

, figureFileSmall=null, figureFileBig=null, tableContent=
植物油种类 总件数 检出率
/%
超标率
/%
含量/(μg/kg)
最小值 平均值 标准差 中位数 P95 最大值
玉米油 20 100.0 5.0 204.0 499.0 280.2 436.0 1498.4 1540.0
大豆油 20 95.0 0.0 ND 238.7 169.2 250.5 792.2 816.0
菜籽油 15 93.3 0.0 ND 102.6 75.9 79.9 299.0 299.0
花生油 15 86.7 0.0 ND 227.4 145.1 225.0 493.0 493.0
橄榄油 15 66.7 0.0 ND 37.7 27.1 40.4 82.9 82.9
葵花籽油 15 100.0 0.0 57.1 176.4 123.0 167.0 466.0 466.0
芝麻油 15 100.0 6.7 60.4 357.2 298.5 256.0 1040.0 1040.0
稻米油 15 100.0 26.7 50.7 1169.3 1599.6 347.0 5470.0 5470.0
食用植物调和油 15 100.0 13.3 76.3 413.6 348.5 318.0 1330.0 1330.0
油茶籽油 13 100.0 15.4 218.0 657.8 710.3 469.0 2870.0 2870.0
亚麻籽油 10 100.0 0.0 40.5 146.4 122.2 103.0 396.0 396.0
核桃油 5 100.0 0.0 44.0 85.7 30.1 98.3 112.0 112.0
其他食用植物油a 5 80.0 0.0 ND 351.2 208.9 376.0 551.0 551.0
合计 178 94.4 5.6 ND 360.8 599.5 241.5 1040.0 5470.0
), ArticleFig(id=1175086848876626558, tenantId=1146029695717560320, journalId=1149652044408987649, articleId=1153433635819606722, language=CN, label=表1, caption=

不同种类食用植物油中GE的污染水平

, figureFileSmall=null, figureFileBig=null, tableContent=
植物油种类 总件数 检出率
/%
超标率
/%
含量/(μg/kg)
最小值 平均值 标准差 中位数 P95 最大值
玉米油 20 100.0 5.0 204.0 499.0 280.2 436.0 1498.4 1540.0
大豆油 20 95.0 0.0 ND 238.7 169.2 250.5 792.2 816.0
菜籽油 15 93.3 0.0 ND 102.6 75.9 79.9 299.0 299.0
花生油 15 86.7 0.0 ND 227.4 145.1 225.0 493.0 493.0
橄榄油 15 66.7 0.0 ND 37.7 27.1 40.4 82.9 82.9
葵花籽油 15 100.0 0.0 57.1 176.4 123.0 167.0 466.0 466.0
芝麻油 15 100.0 6.7 60.4 357.2 298.5 256.0 1040.0 1040.0
稻米油 15 100.0 26.7 50.7 1169.3 1599.6 347.0 5470.0 5470.0
食用植物调和油 15 100.0 13.3 76.3 413.6 348.5 318.0 1330.0 1330.0
油茶籽油 13 100.0 15.4 218.0 657.8 710.3 469.0 2870.0 2870.0
亚麻籽油 10 100.0 0.0 40.5 146.4 122.2 103.0 396.0 396.0
核桃油 5 100.0 0.0 44.0 85.7 30.1 98.3 112.0 112.0
其他食用植物油a 5 80.0 0.0 ND 351.2 208.9 376.0 551.0 551.0
合计 178 94.4 5.6 ND 360.8 599.5 241.5 1040.0 5470.0
), ArticleFig(id=1175086849002455681, tenantId=1146029695717560320, journalId=1149652044408987649, articleId=1153433635819606722, language=EN, label=Table 2, caption=

Contamination levels of GE in edible vegetable oils at different production locations

, figureFileSmall=null, figureFileBig=null, tableContent=
产地 总件数 检出率/% 超标率/% 含量/(μg/kg)
最小值 平均值 标准差 中位数 P95 最大值
国产 160 96.3 6.3 ND 386.0 624.8 260.0 1040.0 5470.0
进口 18 77.8 0.0 ND 136.7 180.5 59.3 551.0 551.0
), ArticleFig(id=1175086849090536068, tenantId=1146029695717560320, journalId=1149652044408987649, articleId=1153433635819606722, language=CN, label=表2, caption=

不同产地食用植物油中GE的污染水平

, figureFileSmall=null, figureFileBig=null, tableContent=
产地 总件数 检出率/% 超标率/% 含量/(μg/kg)
最小值 平均值 标准差 中位数 P95 最大值
国产 160 96.3 6.3 ND 386.0 624.8 260.0 1040.0 5470.0
进口 18 77.8 0.0 ND 136.7 180.5 59.3 551.0 551.0
), ArticleFig(id=1175086849182810759, tenantId=1146029695717560320, journalId=1149652044408987649, articleId=1153433635819606722, language=EN, label=Table 3, caption=

Contamination levels of GE in different brands of edible vegetable oils

, figureFileSmall=null, figureFileBig=null, tableContent=
品牌 总件数 检出率/% 超标率/% 含量/(μg/kg)
最小值 平均值 中位数 最大值
A 15 100.0 6.7 93.5 407.6 332.0 1280.0
B 11 100.0 0.0 57.1 170.0 193.0 348.0
C 8 87.5 12.5 ND 443.9 249.5 1540.0
D 7 100.0 0.0 50.7 271.8 207.0 636.0
E 6 83.3 0.0 ND 177.0 182.4 317.0
F 6 100.0 0.0 58.4 367.1 249.0 816.0
), ArticleFig(id=1175086849279279757, tenantId=1146029695717560320, journalId=1149652044408987649, articleId=1153433635819606722, language=CN, label=表3, caption=

不同品牌食用植物油中GE的污染水平

, figureFileSmall=null, figureFileBig=null, tableContent=
品牌 总件数 检出率/% 超标率/% 含量/(μg/kg)
最小值 平均值 中位数 最大值
A 15 100.0 6.7 93.5 407.6 332.0 1280.0
B 11 100.0 0.0 57.1 170.0 193.0 348.0
C 8 87.5 12.5 ND 443.9 249.5 1540.0
D 7 100.0 0.0 50.7 271.8 207.0 636.0
E 6 83.3 0.0 ND 177.0 182.4 317.0
F 6 100.0 0.0 58.4 367.1 249.0 816.0
), ArticleFig(id=1175086849363165839, tenantId=1146029695717560320, journalId=1149652044408987649, articleId=1153433635819606722, language=EN, label=Table 4, caption=

Daily consumption of edible vegetable oil of Shanghai residents

, figureFileSmall=null, figureFileBig=null, tableContent=
年龄分组/岁 调查人数 消费率/% 平均体质量/kg 消费量/(g/d)
平均值 标准差 中位数 P95 最大值
3~17 113 98.2 35.6 24.4 21.9 20.5 63.9 165.1
18~44 171 98.2 65.0 36.8 29.8 30.0 104.0 165.1
45~59 124 98.4 66.1 30.8 21.8 26.0 68.4 150.0
≥60 118 100.0 63.3 32.0 18.1 29.5 70.3 132.0
合计(≥3) 526 98.7 58.5 31.6 24.4 26.0 80.0 165.1
), ArticleFig(id=1175086849493189266, tenantId=1146029695717560320, journalId=1149652044408987649, articleId=1153433635819606722, language=CN, label=表4, caption=

上海市居民每日食用植物油的消费量

, figureFileSmall=null, figureFileBig=null, tableContent=
年龄分组/岁 调查人数 消费率/% 平均体质量/kg 消费量/(g/d)
平均值 标准差 中位数 P95 最大值
3~17 113 98.2 35.6 24.4 21.9 20.5 63.9 165.1
18~44 171 98.2 65.0 36.8 29.8 30.0 104.0 165.1
45~59 124 98.4 66.1 30.8 21.8 26.0 68.4 150.0
≥60 118 100.0 63.3 32.0 18.1 29.5 70.3 132.0
合计(≥3) 526 98.7 58.5 31.6 24.4 26.0 80.0 165.1
), ArticleFig(id=1175086849551909528, tenantId=1146029695717560320, journalId=1149652044408987649, articleId=1153433635819606722, language=EN, label=Table 5, caption=

Daily dietary GE exposure and MOE values of Shanghai residents through edible vegetable oil

, figureFileSmall=null, figureFileBig=null, tableContent=
年龄分组/岁 调查人数 膳食暴露量/(μg/kg bw) MOE
平均值 中位数 P95 平均值 中位数 P95
3~17 113 0.275 0.227 0.682 8727 10573 3519
18~44 171 0.209 0.162 0.608 11483 14815 3947
45~59 124 0.169 0.141 0.371 14201 17021 6469
≥60 118 0.183 0.167 0.372 13115 14371 6452
合计(≥3) 526 0.208 0.165 0.497 11538 14545 4829
), ArticleFig(id=1175086849631601306, tenantId=1146029695717560320, journalId=1149652044408987649, articleId=1153433635819606722, language=CN, label=表5, caption=

上海市居民每日经食用植物油摄入GE的膳食暴露量和MOE值

, figureFileSmall=null, figureFileBig=null, tableContent=
年龄分组/岁 调查人数 膳食暴露量/(μg/kg bw) MOE
平均值 中位数 P95 平均值 中位数 P95
3~17 113 0.275 0.227 0.682 8727 10573 3519
18~44 171 0.209 0.162 0.608 11483 14815 3947
45~59 124 0.169 0.141 0.371 14201 17021 6469
≥60 118 0.183 0.167 0.372 13115 14371 6452
合计(≥3) 526 0.208 0.165 0.497 11538 14545 4829
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上海市市售食用植物油中缩水甘油酯的污染水平和膳食暴露评估
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宇盛好 , 彭少杰 *
食品安全质量检测学报 | 本期专题:食品安全风险评估与风险监测 2025,16(6): 52-58
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食品安全质量检测学报 | 本期专题:食品安全风险评估与风险监测 2025, 16(6): 52-58
上海市市售食用植物油中缩水甘油酯的污染水平和膳食暴露评估
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宇盛好 , 彭少杰*
作者信息
  • 上海市市场监督管理局信息应用研究中心, 上海 200030
  • 宇盛好(1990—), 男, 硕士, 工程师, 主要研究方向为食品安全风险监测与评估。E-mail:

通讯作者:

* 彭少杰(1968—), 男, 硕士, 主任医师, 主要研究方向为食品安全风险监测与评估。E-mail:
Contamination level and dietary exposure assessment of glycidyl esters in edible vegetable oils sold in Shanghai
Sheng-Hao YU , Shao-Jie PENG*
Affiliations
  • Information Application Research Center of Shanghai Municipal Administration for Market Regulation, Shanghai 200030, China
出版时间: 2025-03-25 doi: 10.19812/j.cnki.jfsq11-5956/ts.20241118007
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目的 了解上海居民食用植物油中缩水甘油酯(glycidyl esters, GE)的污染水平, 评估上海居民GE的膳食暴露风险。方法 利用2024年上海市市售食用植物油中GE的监测数据, 结合2024年上海居民植物油消费量数据, 采用简单分布评估法计算上海居民经植物油摄入GE的暴露量, 并用暴露边界比(margin of exposure, MOE)法评估健康风险。结果 178件食用植物油中GE的检出率为94.4%, 含量均值为360.8 μg/kg, 最大值为5470.0 μg/kg。参照欧盟法规规定的植物油中GE的限量值进行评价, 发现样品中GE的超标率为5.6%。稻米油中GE的含量均值(1169.3 μg/kg)最高, 其次为油茶籽油(657.8 μg/kg)和玉米油(499.0 μg/kg)。上海≥3岁居民每日通过食用植物油摄入GE的平均暴露量和P95暴露量分别为0.208和0.497 μg/kg bw, MOE值分别为11538和4829, P95 MOE小于10000。3~17岁居民经植物油摄入GE的平均MOE值小于10000。4个不同年龄组居民经植物油摄入GE的P95 MOE值均小于10000。结论 上海居民经植物油摄入GE的健康风险总体上处于可接受水平。但对于3~17岁人群以及植物油高消费人群GE暴露的健康风险仍需重点关注。

食用植物油  /  缩水甘油酯  /  污染水平  /  暴露评估  /  暴露边界比

Objective To understand the contamination level of glycidyl esters (GE) in edible vegetable oils and to evaluate the dietary exposure risk of GE in Shanghai residents. Methods Based on the monitoring data of GE in edible vegetable oil sold in Shanghai in 2024, combined with the vegetable oil consumption data of Shanghai residents in 2024, the GE exposure of Shanghai residents via vegetable oil was calculated by simple distribution assessment method, and the margin of exposure (MOE) method was used to assess the health risk. Results The detection rate of GE in 178 edible vegetable oils was 94.4%, with an average content of 360.8 μg/kg and a maximum value of 5470.0 μg/kg. According to the EU regulations on the limit values of GE in vegetable oils, it was found that the exceeding standard rate of GE in vegetable oil was 5.6%. The mean content of GE in rice oil (1169.3 μg/kg) was the highest, followed by camellia seed oil (657.8 μg/kg) and corn oil (499.0 μg/kg). The mean daily exposure and 95th percentile exposure of GE from edible vegetable oils in Shanghai residents aged ≥3 years old were 0.208 and 0.497 μg/kg bw, the MOE values were 11538 and 4829, respectively, and P95 MOE was less than 10000. The mean MOE value of GE exposure through vegetable oil in residents aged 3 to 17 years old was less than 10000. The P95 MOE values of GE exposure through vegetable oil in 4 different age groups were all less than 10000. Conclusion The health risk of GE intake via edible vegetable oil in Shanghai residents is generally at an acceptable level. However, the health risks of GE exposure for individuals aged 3 to 17 year old and those with high consumption of vegetable oil still need to be focused.

edible vegetable oil  /  glycidyl esters  /  contamination level  /  exposure assessment  /  margin of exposure
宇盛好, 彭少杰. 上海市市售食用植物油中缩水甘油酯的污染水平和膳食暴露评估. 食品安全质量检测学报, 2025 , 16 (6) : 52 -58 . DOI: 10.19812/j.cnki.jfsq11-5956/ts.20241118007
Sheng-Hao YU, Shao-Jie PENG. Contamination level and dietary exposure assessment of glycidyl esters in edible vegetable oils sold in Shanghai[J]. Journal of Food Safety & Quality, 2025 , 16 (6) : 52 -58 . DOI: 10.19812/j.cnki.jfsq11-5956/ts.20241118007
缩水甘油酯(glycidyl esters, GE)是植物油在精炼或者热加工过程中产生的新型污染物[1-3]。在植物油精炼过程中, GE和3-氯-1,2-丙二醇酯(3-monochloropropane-1,2-diol esters, 3-MCPDE)通常一起产生, 在特定条件下GE和3-MCPDE可以互相转化[4-5]。GE在人体中会代谢为缩水甘油(glycidol, Gly), Gly具有神经毒性、遗传毒性和致癌性等[6-9], 并且2000年国际癌症研究机构(International Agency for Research on Cancer, IARC)已将Gly列为2A类致癌物[9]。2016年, 欧洲食品安全局(European Food Safety Authority, EFSA)基于大鼠长期暴露Gly引起的25%肿瘤发生率, 建立了Gly的基准剂量T25为10.2 mg/kg bw[8]。2016年, 联合国粮农组织/世界卫生组织食品添加剂联合专家委员会(Joint FAO/WHO Expert Committee on Food and Additives, JECFA)制定了Gly的基准剂量可信区间下限值(benchmark dose lower confidence limit 10%, BMDL10)为2.4 mg/kg bw[10]
食用植物油[11-12]、油炸食品[13-14]、熏烤食品[13]、饼干[15]、面包[15]以及婴幼儿配方乳粉[16-17]等含油脂食品中普遍存在GE污染。刘卿等[5]报道了我国2015—2017年市售397件植物油中GE的超标率为19.9%, 含量均值为680 μg/kg, 最大值为7360 μg/kg。目前, 我国还缺乏植物油中GE的限量标准和控制规范。2023年, 欧盟(EU)2023/915《关于食品中某些污染物最高含量的条例》规定植物油中GE(以Gly计)的最大限量为1000 μg/kg, 并规定生产婴儿食品和婴幼儿谷类食品的植物油中GE的限量值为500 μg/kg[18]。植物油作为我国居民饮食的重要组成部分, 其质量安全直接关系到居民的身体健康。
鉴于此, 本研究对上海市市售食用植物油中GE的污染情况进行分析, 结合上海居民植物油消费量数据, 采用简单分布评估法计算上海居民经植物油摄入GE的暴露水平, 并采用暴露边界比法(margin of exposure, MOE)评估上海居民健康风险, 为植物油中GE安全监管以及限量标准制定提供参考。
2024年共监测上海市市售食用植物油样品178件。按照植物油的种类分类, 包括玉米油、大豆油、菜籽油、花生油等14种。样品随机采集于上海市的超市、农贸市场、批发市场、食品店以及网店等。样品覆盖了上海市场上销售的91个植物油品牌。样品生产加工工艺主要包括压榨、浸出以及水代法等。按照样品产地分, 包括国产和进口样品。其中, 国产样品产地包括上海、江苏、安徽、山东、浙江、河南、江西等21个省(自治区、直辖市), 进口样品产地包括西班牙、意大利、法国、新加坡4个国家。
植物油样品中GE含量委托上海市食品药品检验研究院进行检验。植物油中GE检验方法为《2022年国家食品污染和有害因素风险监测工作手册(中卷)》(食品中氯丙醇酯和缩水甘油酯含量测定的标准操作程序 13C同位素稀释-气相色谱-串联质谱法)[19], GE(以Gly计)的检出限和定量限分别为10 μg/kg和30 μg/kg。本研究参照欧盟关于植物油中GE的最大限量(1000 μg/kg)对样品中GE的检测值进行评价。
上海居民每日食用植物油的消费量数据采用2024年4月—2024年7月本单位委托上海质协用户评价中心开展的上海居民食用植物油消费量调查数据。调查方法为在上海的16个区随机选择愿意配合消费量调查的居民, 采用食物称重法计算居民24 h植物油的消费量。共调查3~93岁居民526名, 平均体重为58.5 kg。按照年龄段分, 3~17岁、18~44岁、45~59岁、≥60岁居民的调查人数分别为113、171、124和118人。按照性别分, 男性和女性分别调查了254和272人。
采用简单分布评估方法计算上海居民通过食用植物油摄入GE的膳食暴露量, 暴露量的计算公式如式(1)所示:
$E=\frac{C\times F}{\text{W}\times 1000}$
式中: E为上海居民个体每日每kg体质量GE的膳食暴露量, μg/kg bw; C为植物油中GE的平均含量, μg/kg; F为某个体每日植物油的消费量, g/d; W为个体的体质量, kg。
在得到居民个体通过植物油摄入GE暴露量的基础上, 最终可获得上海居民GE暴露量的频数分布, 可计算不同年龄段居民经植物油摄入GE暴露量的平均值、中位数和P95值等。
本研究采用MOE法来评价GE的膳食暴露风险。本研究采用JECFA制定的Gly的BMDL10 (2.4 mg/kg bw)来计算GE的MOE值。当MOE<10000时, 表示存在一定的健康风险, 需要重点关注; 当MOE≥10000时, 表示健康风险处于可接受水平[20]。MOE的计算公式如式(2)所示。
$MOE=\frac{BMD{{L}_{10}}}{E}$
本研究采用世界卫生组织对食品中污染物的未检出值(not detected, ND)处理原则对样品中ND值进行处理[21], 本次评估对于植物油中GE的ND值以检出限的一半(即5.0 μg/kg)替代。运用WPS Office 2024和SPSS 28.0软件对样品监测数据进行统计分析。样品中GE检出率差异比较采用卡方检验(χ2), 但对于不满足卡方检验要求的(如超过20%单元格的理论频数T小于5或至少1个T小于1), 则采用Fisher确切概率法检验。不同种类、不同品牌样品中GE的含量差异比较采用Kruskal-Wallis H检验。采用Kruskal-Wallis H检验比较不同年龄段居民植物油消费量的差异。采用Kruskal-Wallis H检验比较不同年龄段居民GE暴露量的差异。不同产地样品中GE的含量差异比较采用Mann-Whitney U检验。当P<0.05时, 表明差异有统计学意义。
2024年上海市市售178件食用植物油中GE的总体检出率为94.4%(168/178), 含量均值为360.8 μg/kg, 中位数为241.5 μg/kg, 最大值为5470.0 μg/kg, 植物油中GE含量的频数分布见图1。若参照欧盟关于植物油中GE的限量标准对样品中GE检验结果进行评价, GE超标率为5.6% (10/178)。本次植物油中GE含量的最大值(5470.0 μg/kg)出现在1件稻米油中, 为GE的最大限量值(1000 μg/kg)的5.47倍(表1)。
总体上, 不同种类植物油中GE的检出率差异有统计学意义(P<0.05)。其中, 玉米油、葵花籽油、芝麻油、稻米油、食用植物调和油、油茶籽油、亚麻籽油和核桃油中GE的检出率较高, 均为100.0%, 橄榄油中GE的检出率(66.7%)最低。稻米油中GE的超标率(26.7%)最高, 其次为油茶籽油(15.4%)和食用植物调和油(13.3%)。总体上, 不同种类植物油中GE含量差异显著(H=89.635, P<0.05)。其中, 稻米油中GE的含量均值(1169.3 μg/kg)最高, 其次为油茶籽油(657.8 μg/kg)和玉米油(499.0 μg/kg), 橄榄油中GE的含量均值最低(37.7 μg/kg)。具体结果见表1
国产食用植物油中GE的检出率(96.3%)高于进口样品(77.8%) (χ2=7.220, P<0.05)。国产植物油中GE的超标率(6.3%)高于进口样品(0.0%)。国产植物油中GE的含量均值(386.0 μg/kg)高于进口样品(136.7 μg/kg) (Z=-3.508, P<0.05)。具体结果见表2。国产和进口植物油中GE的含量存在差异主要与不同产地植物油种类构成不同有关。本次监测的国产样品包括14个植物油品种, 而进口样品仅监测5个植物油品种(包含橄榄油12件、核桃油2件、葡萄籽油2件、芝麻油1件和牛油果油1件)。
选择样本量≥6件的6个植物油品牌进行统计分析。由表3可知: 6个不同种品牌植物油中GE的检出率范围为83.3%~100.0%, 但不同品牌样品中GE的检出率差异没有统计学意义(P>0.05)。C品牌植物油中GE含量均值(443.9 μg/kg)在6个品牌中最高, 其次为A品牌植物油(407.6 μg/kg), 最低的为B品牌植物油(170.0 μg/kg), 但不同品牌植物油中GE含量差异无统计学意义(H=9.617, P>0.05)。B、D、E、F品牌植物油中GE含量均未超标, 而C和A品牌植物油中存在GE超标情况, 超标率分别为12.5% (1/8)和6.7% (1/15)。
本研究共调查上海居民526人, 其中有519人在调查当天食用了植物油, 总体消费率为98.7% (519/526)。上海市≥3岁居民每日食用植物油的消费量均值和P95值分别为31.6 g/d和80.0 g/d。上海市不同年龄段居民每日植物油消费量差异有统计学意义(H=25.756, P<0.05)。上海市3~17岁、18~44岁、45~59岁和≥60岁居民植物油的消费量均值分别为24.4、36.8、30.8和32.0 g/d。结果见表4
表5可知: 上海市≥3岁居民每日经食用植物油摄入GE的平均暴露量和P95暴露量分别为0.208和0.497 μg/kg bw, 平均MOE值(11538)大于10000, P95 MOE值(4829)小于10000, 表明本市居民暴露于GE的健康风险总体上处于可接受水平, 但植物油高消费人群存在一定的健康风险。总体上, 上海市不同年龄段居民每日通过植物油摄入GE的暴露量差异显著(H=21.150, P<0.05)。3~17岁居民每日通过植物油摄入GE的平均暴露量为0.275 μg/kg bw, 平均MOE值小于10000, 健康风险需要重点关注。4个不同年龄组(3~17岁、18~44岁、45~59岁、≥60岁)居民每日通过食用植物油摄入GE的P95 暴露量范围为0.371~0.682 μg/kg bw, P95 MOE值(3519~6469)均小于10000, 表明高消费人群的健康风险需要重点关注。
本研究分析了2024年上海市市售食用植物油中GE的污染状况, 发现178件植物油中GE的检出率为94.4%, 表明植物油普遍存在GE污染。按照欧盟规定的植物油中GE的最大限量值进行评价, 178件样品中GE的超标率为5.6%, 并且发现稻米油中GE的超标率(26.7%)最高, 其次为油茶籽油和食用植物调和油。不同品种植物油中GE污染水平不同。其中, 稻米油中GE的含量均值最高, 其次为油茶籽油和玉米油, GE含量均值最低为橄榄油。植物油中GE主要产生于植物油精炼的脱臭阶段, 脱臭温度和脱臭时间均会显著影响植物油中GE形成[22-23]。不同种类植物油的GE含量差异较大可能主要与植物油加工工艺、毛油中甘油酯组成(如甘油一酯、甘油二酯等)、游离脂肪酸含量以及油料中氯离子含量不同有关[5,22]
本研究植物油中GE的含量均值为360.8 μg/kg, 低于刘卿等[5]报道的我国市售397件植物油中GE的含量均值(680 μg/kg), 低于2021—2022年天津市市售137件植物油中GE的含量均值(940 μg/kg)[24], 低于2019—2023年济南市市售142件植物油中GE的含量均值(1410 μg/kg)[25], 低于樊继彩等[26]报道的市售94件植物油中GE的含量均值(710 μg/kg), 低于SHI等[27]报道的新加坡市售36件精炼植物油中GE的含量均值(1317.2 μg/kg), 低于张波等[28]报道的承德市市售30件植物油中GE的含量均值(550 μg/kg)。
上海市≥3岁居民每日经植物油摄入GE的平均暴露量为0.208 μg/kg bw, 平均MOE值大于10000, P95暴露量为0.497 μg/kg bw, P95 MOE值小于10000, 表明植物油高消费人群存在一定的健康风险。若采用EFSA规定Gly的T25值(10.2 mg/kg bw)来计算GE的MOE值, 发现上海居民经植物油暴露GE的平均MOE和P95 MOE值分别为49038和20523, 平均MOE值大于25000, 而P95 MOE值小于25000, 表明高消费人群的健康风险需要关注。LIAO等[24]报道了天津市不同年龄组居民(7~10岁、11~13岁、14~17岁、18~70岁)经植物油摄入GE的平均暴露量范围为0.53~0.86 μg/kg bw, P95暴露量范围为1.24~2.01 μg/kg bw。不同研究中GE暴露量差异主要与不同研究中居民植物油消费量以及植物油中GE含量不同有关。
本研究评估存在一定的不确定性: (1)本次监测植物油样本量(178件)偏少, 覆盖了91个植物油品牌, 但部分品牌的样本量偏少, 导致评估存在一定的不确定性; (2)本次仅考虑植物油中GE的暴露量, 未考虑其他含油脂食品中GE的膳食暴露量, 也没有植物油烹调过程中GE含量变化, 可能存在一定的不确定性; (3)本次上海居民的食用植物油消费量调查的人数(526人)偏少, 并且仅调查居民一天的植物油消费量, 存在一定的不确定性。
针对食用植物油中GE的污染现状, 本研究提出以下建议: (1)植物油生产企业要强化油料的把控, 降低毛油中前体物质(如甘油一酯、甘油二酯)的含量[22,29-30], 加强脱色、脱臭等生产加工环节的过程控制(如降低精炼温度和缩短精炼时间, 植物油的脱臭温度不宜超过230 ℃)[30], 加强生产用水中氯离子浓度的控制, 还可以采用分子蒸馏[23]、短程蒸馏、物理吸附(如活性炭、活性白土、硅胶、凹凸棒土等)[23,31]、添加抗氧化剂(如丁基羟基茴香醚、二丁基羟基甲苯、迷迭香提取物、茶多酚等)[32]等方法降低植物油中GE含量, 加强植物油中GE的出厂检验, 通过采取综合措施降低植物油中GE的含量; (2)政府部门要加强重点植物油品种(如稻米油、油茶籽油和玉米油等)中GE的安全监管、抽检监测和风险评估, 制定限量标准或控制规范来进一步降低植物油中GE含量。(3)加大植物油中GE的科普宣传力度, 建议居民食用不同种类的植物油, 并减少食用植物油的消费总量(如成人每天食用油摄入量不要超过30 g)。
  • 2024年度上海市市场监督管理局科技项目(2024-51)
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2025年第16卷第6期
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doi: 10.19812/j.cnki.jfsq11-5956/ts.20241118007
  • 接收时间:2024-11-18
  • 首发时间:2025-07-19
  • 出版时间:2025-03-25
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  • 收稿日期:2024-11-18
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2024年度上海市市场监督管理局科技项目(2024-51)
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    上海市市场监督管理局信息应用研究中心, 上海 200030

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* 彭少杰(1968—), 男, 硕士, 主任医师, 主要研究方向为食品安全风险监测与评估。E-mail:
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Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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