Research

Research ›› 2025, Vol. 8 ›› Issue (8) : 0817 - . DOI: 10.34133/research.0817

Research Article

An Explainable Two-Stage Machine Learning Model for Predicting the Post-Thrombolysis Complications in Stroke Patients: A Multi-Center Study

Hongling Zhu ¹ ,
Qing Ye ² ,
Shurui Wang ² ,
Hongsen Cai ³ ,
Mairihaba Maimaiti ¹ ,
Jinsheng Lai ¹ ,
Chuan Qin ⁴ ,
Ping Zhang ⁴ ,
Yanyan Chen ² ,
Qiushi Luo ¹ ,
Hong Wu ⁵ ,
Danyang Chen ⁴ ,
Shiling Chen ⁴ ,
Shudan Zhu ⁵ ,
Yuting Lv ⁶ ,
Yanxiang Xu ⁶ ,
Jian Zhang ⁷ ,
Benshan Hu ⁷ ,
Yuanxiang Yin ⁷ ,
Yan Xie ⁷ ,
Dongmei Zhu ⁸ ,
Xiaoxing Ming ⁶ ,
Zhouping Tang ⁴^,^* ,
Hesong Zeng ¹^,^*

Author information +

¹Division of Cardiology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, P.R. China.

²Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, P.R. China.

³College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, P.R. China.

⁴Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, P.R. China.

⁵School of Medicine and Health Management, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, P.R. China.

⁶Department of Medical Imaging, Yangxin County People’s Hospital, Huangshi, Hubei 435200, P.R. China.

⁷Department of Neurology, Xiantao First People’s Hospital Affiliated to Hubei University of Science and Technology, Xiantao, 433000 Hubei, P.R. China.

⁸Department of Cardiology, Xiantao First People’s Hospital Affiliated to Hubei University of Science and Technology, Xiantao 433000, Hubei, P.R. China.

^* Address correspondence to: zenghs@tjh.tjmu.edu.cn (H.Z.);

ddjtzp@163.com (Z.T.)

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Received	Accepted	Published
2024-11-20	2025-07-11
Issue Date
2026-11-02

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