Research

Research ›› 2025, Vol. 8 ›› Issue (11) : 0996 - . DOI: 10.34133/research.0996

Research Article

Targeting Matrix Metalloproteinase-9 to Alleviate T Cell Exhaustion and Improve Sepsis Prognosis

Xuan Wang ¹^,² ,
Jingyuan Ning ³ ,
Liang Zhou ⁴ ,
Hongru Li ¹ ,
Jinlei Cui ¹ ,
Jiachao Wang ¹ ,
Xiangyang Liang ¹^,⁵ ,
Jinquan Li ⁶ ,
Miao Li ¹ ,
Xue Gao ¹ ,
Wenjian Li ¹ ,
Xing Chen ⁷ ,
Fei Yu ⁸ ,
Lin Wei ¹^,^* ,
Cuiqing Ma ¹^,^*

Author information +

¹Key Laboratory of Immune Mechanism and Intervention on Serious Disease in Hebei Province, Department of Immunology, Hebei Medical University, Shijiazhuang, PR China.

²Diagnostic Center of Infections, The Second Hospital of Hebei Medical University, Shijiazhuang, PR China.

³Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, PR China.

⁴Department of Reproductive Medicine, The Second Hospital of Hebei Medical University, Shijiazhuang, PR China.

⁵School and Hospital of Stomatology, Hebei Medical University, Shijiazhuang, Hebei, PR China.

⁶State Key Laboratory of Agricultural Microbiology, College of Food Science and Technology, Huazhong Agricultural University, Wuhan, Hubei, PR China.

⁷Shijiazhuang Heya Biotechnology Co., LTD, Shijiazhuang, PR China.

⁸Hebei Key Laboratory of Analysis and Control of Zoonotic Pathogenic Microorganism, College of Life Sciences, Hebei Agricultural University, Baoding, PR China.

^* Address correspondence to: weilin@hebmu.edu.cn (L.W.);

macuiqing@hebmu.edu.cn (C.M.)

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Received	Accepted	Published
2025-09-01	2025-10-30
Issue Date
2026-11-02

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